Genetic detection of Dobrava-Belgrade hantavirus in the edible dormouse (Glis glis) in central Serbia
Hantaviruses are endemic in the Balkans, particularly in Serbia, where sporadic cases and/or outbreaks of hantaviral human disease have been reported repeatedly, and evidenced serologically. Here, we present genetic detection of Dobrava-Belgrade virus (DOBV) hantaviral sequences in wild rodents trap...
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ftinstbiss:oai:radar.ibiss.bg.ac.rs:123456789/2091 2023-05-15T17:12:34+02:00 Genetic detection of Dobrava-Belgrade hantavirus in the edible dormouse (Glis glis) in central Serbia Stanojevic, M. Nikolic, V. Stajkovic, N. Stamenković, Gorana Bozovic, B. Cekanac, R. Marusic, P. Gligic, A. 2016-05-23T11:00:11Z https://radar.ibiss.bg.ac.rs/handle/123456789/2091 https://doi.org/10.1017/S0950268814001010 English eng 1469-4409 https://radar.ibiss.bg.ac.rs/handle/123456789/2091 doi:10.1017/S0950268814001010 2-s2.0-84925230419 000348642600021 restrictedAccess ARR Epidemiology and Infection Balkans Glis glis article publishedVersion 2016 ftinstbiss https://doi.org/10.1017/S0950268814001010 2023-03-08T15:01:20Z Hantaviruses are endemic in the Balkans, particularly in Serbia, where sporadic cases and/or outbreaks of hantaviral human disease have been reported repeatedly, and evidenced serologically. Here, we present genetic detection of Dobrava-Belgrade virus (DOBV) hantaviral sequences in wild rodents trapped in central Serbia. All the animals were pre-screened serologically by indirect immunofluorescence (IF) test and only those with a positive finding of hantaviral antigens were further tested by polymerase chain reaction. Of the total of 104 trapped animals, 20 were found to be IF positive and of those three were positive for hantaviral RNA: one Microtus arvalis for Tula virus, and one each of Apodemus agrarius and Glis glis for DOBV. Phylogenetic analysis of the obtained sequences implies putative DOBV spillover infection of A. agrarius and G. glis from Apodemus flavicollis. However, future investigations should help to identify the most common natural host and geographical distribution of DOBV in its reservoir hosts in Serbia. Ministry of Education and Science Republic of Serbia {[}175024] Article in Journal/Newspaper Microtus arvalis RADaR - Digital Repository of Archived Publications Institute for Biological Research "Sinisa Stankovic" Tula ENVELOPE(-65.650,-65.650,-65.517,-65.517) Epidemiology and Infection 143 2 400 404 |
institution |
Open Polar |
collection |
RADaR - Digital Repository of Archived Publications Institute for Biological Research "Sinisa Stankovic" |
op_collection_id |
ftinstbiss |
language |
English |
topic |
Balkans Glis glis |
spellingShingle |
Balkans Glis glis Stanojevic, M. Nikolic, V. Stajkovic, N. Stamenković, Gorana Bozovic, B. Cekanac, R. Marusic, P. Gligic, A. Genetic detection of Dobrava-Belgrade hantavirus in the edible dormouse (Glis glis) in central Serbia |
topic_facet |
Balkans Glis glis |
description |
Hantaviruses are endemic in the Balkans, particularly in Serbia, where sporadic cases and/or outbreaks of hantaviral human disease have been reported repeatedly, and evidenced serologically. Here, we present genetic detection of Dobrava-Belgrade virus (DOBV) hantaviral sequences in wild rodents trapped in central Serbia. All the animals were pre-screened serologically by indirect immunofluorescence (IF) test and only those with a positive finding of hantaviral antigens were further tested by polymerase chain reaction. Of the total of 104 trapped animals, 20 were found to be IF positive and of those three were positive for hantaviral RNA: one Microtus arvalis for Tula virus, and one each of Apodemus agrarius and Glis glis for DOBV. Phylogenetic analysis of the obtained sequences implies putative DOBV spillover infection of A. agrarius and G. glis from Apodemus flavicollis. However, future investigations should help to identify the most common natural host and geographical distribution of DOBV in its reservoir hosts in Serbia. Ministry of Education and Science Republic of Serbia {[}175024] |
format |
Article in Journal/Newspaper |
author |
Stanojevic, M. Nikolic, V. Stajkovic, N. Stamenković, Gorana Bozovic, B. Cekanac, R. Marusic, P. Gligic, A. |
author_facet |
Stanojevic, M. Nikolic, V. Stajkovic, N. Stamenković, Gorana Bozovic, B. Cekanac, R. Marusic, P. Gligic, A. |
author_sort |
Stanojevic, M. |
title |
Genetic detection of Dobrava-Belgrade hantavirus in the edible dormouse (Glis glis) in central Serbia |
title_short |
Genetic detection of Dobrava-Belgrade hantavirus in the edible dormouse (Glis glis) in central Serbia |
title_full |
Genetic detection of Dobrava-Belgrade hantavirus in the edible dormouse (Glis glis) in central Serbia |
title_fullStr |
Genetic detection of Dobrava-Belgrade hantavirus in the edible dormouse (Glis glis) in central Serbia |
title_full_unstemmed |
Genetic detection of Dobrava-Belgrade hantavirus in the edible dormouse (Glis glis) in central Serbia |
title_sort |
genetic detection of dobrava-belgrade hantavirus in the edible dormouse (glis glis) in central serbia |
publishDate |
2016 |
url |
https://radar.ibiss.bg.ac.rs/handle/123456789/2091 https://doi.org/10.1017/S0950268814001010 |
long_lat |
ENVELOPE(-65.650,-65.650,-65.517,-65.517) |
geographic |
Tula |
geographic_facet |
Tula |
genre |
Microtus arvalis |
genre_facet |
Microtus arvalis |
op_source |
Epidemiology and Infection |
op_relation |
1469-4409 https://radar.ibiss.bg.ac.rs/handle/123456789/2091 doi:10.1017/S0950268814001010 2-s2.0-84925230419 000348642600021 |
op_rights |
restrictedAccess ARR |
op_doi |
https://doi.org/10.1017/S0950268814001010 |
container_title |
Epidemiology and Infection |
container_volume |
143 |
container_issue |
2 |
container_start_page |
400 |
op_container_end_page |
404 |
_version_ |
1766069354240147456 |