Preliminary insights into the genetics of bank vole tolerance to Puumala hantavirus in Sweden

• Published in: Ecology and Evolution
• Main Authors: Rohfritsch, Audrey, Galan, Maxime, Gautier, Mathieu, Gharbi, Karim, Olsson, Gert, Gschloessl, Bernhard, Zeimes, Caroline, Vanwambeke, Sophie, Vitalis, Renaud, Charbonnel, Nathalie
• Other Authors: Centre de Biologie pour la Gestion des Populations (UMR CBGP), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut National de la Recherche Agronomique (INRA)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Université de Montpellier (UM)-Institut de Recherche pour le Développement (IRD France-Sud )-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Earlham Institute Norwich, Department of Wildlife, Fish and Environmental Studies, Swedish University of Agricultural Sciences = Sveriges lantbruksuniversitet (SLU), Centre Georges Lemaître for Earth and Climate Research Louvain (TECLIM), Earth and Life Institute Louvain-La-Neuve (ELI), Université Catholique de Louvain = Catholic University of Louvain (UCL)-Université Catholique de Louvain = Catholic University of Louvain (UCL), European Project: 261504,EC:FP7:HEALTH,FP7-HEALTH-2010-single-stage,EDENEXT(2011)
• Format: Article in Journal/Newspaper
• Language: English
• Published: HAL CCSD 2018
• Subjects: adaptation; hantavirus; immunity; RAD sequencing; selection; molecular epidemiology; tolerance; voles; [SDV.GEN.GPO]Life Sciences [q-bio]/Genetics/Populations and Evolution [q-bio.PE]; [SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]; [SDE.BE]Environmental Sciences/Biodiversity and Ecology; Northern Bank; Northern Sweden
• Online Access: https://hal.science/hal-02388043; https://hal.science/hal-02388043/document; https://hal.science/hal-02388043/file/Rohfritsch_et_al_2018_EcolEvol.pdf; https://doi.org/10.1002/ece3.4603

International audience Natural reservoirs of zoonotic pathogens generally seem to be capable of tolerating infections. Tolerance and its underlying mechanisms remain difficult to assess using experiments or wildlife surveys. High-throughput sequencing technologies give the opportunity to investigate...