PM10 exposure interacts with abdominal obesity to increase blood triglycerides: a cross-sectional linkage study
Background: Blood lipids and glucose levels dysregulation represent potential mechanisms intermediating the adverse cardiovascular effects of ambient particulate matter (PM) exposure. This study aims to estimate the effect of long-term PM10 exposure on blood lipids and glucose levels and to assess t...
Published in: | European Journal of Public Health |
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Language: | English |
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Oxford University Press/ European Public Health Association
2021
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Online Access: | http://hdl.handle.net/10400.18/7834 https://doi.org/10.1093/eurpub/ckab190 |
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ftinssaudelisboa:oai:repositorio.insa.pt:10400.18/7834 2024-01-28T10:06:48+01:00 PM10 exposure interacts with abdominal obesity to increase blood triglycerides: a cross-sectional linkage study Gaio, Vânia Roquette, Rita Monteiro, Alexandra Ferreira, Joana Lopes, Diogo Dias, Carlos Matias Nunes, Baltazar 2021-12-23T16:36:34Z http://hdl.handle.net/10400.18/7834 https://doi.org/10.1093/eurpub/ckab190 eng eng Oxford University Press/ European Public Health Association info:eu-repo/grantAgreement/FCT/OE/SFRH%2FBD%2F129426%2F2017/PT info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F50017%2F2020/PT info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F50017%2F2020/PT https://academic.oup.com/eurpub/advance-article-abstract/doi/10.1093/eurpub/ckab190/6425628?redirectedFrom=fulltext Eur J Public Health. 2022 Apr 1;32(2):281-288. doi:10.1093/eurpub/ckab190. Epub 2021 Nov 11. 1101-1262 http://hdl.handle.net/10400.18/7834 doi:10.1093/eurpub/ckab190 1464-360X openAccess Abdominal Obesity Blood Triglycerides Ambient Particulate Matter Determinantes da Saúde e da Doença Saúde Pública article 2021 ftinssaudelisboa https://doi.org/10.1093/eurpub/ckab190 2024-01-03T01:09:05Z Background: Blood lipids and glucose levels dysregulation represent potential mechanisms intermediating the adverse cardiovascular effects of ambient particulate matter (PM) exposure. This study aims to estimate the effect of long-term PM10 exposure on blood lipids and glucose levels and to assess the potential mediation and/or modification action of abdominal obesity (AO) (waist-to-height ratio). Methods: Our study was based on 2,390 participants of the first Portuguese Health Examination Survey (INSEF, 2015) with available data on blood lipids and glucose parameters and living within a 30-km radius of an air quality monitoring station with available PM10 measurements. PM10 concentrations were acquired from the air quality monitoring network of the Portuguese Environment Agency. Generalized linear models were used to assess the effect of 1-year PM10 exposure on blood lipids and glucose levels. An interaction term was introduced in the models to test the modification action of AO. Results: We found an association between PM10 and non-fasting blood triglycerides (TG) after adjustment for age, sex, education, occupation, lifestyles-related variables and temperature but only in participants with AO. Per each 1 mg/m3 PM10 increment, there was a 1.84% (95% confidence interval: 0.02–3.69) increase in TG. For the remaining blood lipid and glucose parameters, no associations were found. Conclusions: Our study demonstrates that even at low levels of exposure, long-term PM10 exposure interacts with AO to increase blood TG. Our findings suggest that reducing both AO prevalence and PM10 below current standards would result in additional health benefits for the population. INSEF was developed as part of the Pre-defined project financed under the Public Health Initiatives Programme ‘Improvement of epidemiological health information to support public health decision and management in Portugal. Towards reduced inequalities, improved health and bilateral cooperation’ with a 1.500.000e Grant from Iceland, Liechtenstein and ... Article in Journal/Newspaper Iceland National Health Institute, Portugal: Repositório Científico European Journal of Public Health 32 2 281 288 |
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Open Polar |
collection |
National Health Institute, Portugal: Repositório Científico |
op_collection_id |
ftinssaudelisboa |
language |
English |
topic |
Abdominal Obesity Blood Triglycerides Ambient Particulate Matter Determinantes da Saúde e da Doença Saúde Pública |
spellingShingle |
Abdominal Obesity Blood Triglycerides Ambient Particulate Matter Determinantes da Saúde e da Doença Saúde Pública Gaio, Vânia Roquette, Rita Monteiro, Alexandra Ferreira, Joana Lopes, Diogo Dias, Carlos Matias Nunes, Baltazar PM10 exposure interacts with abdominal obesity to increase blood triglycerides: a cross-sectional linkage study |
topic_facet |
Abdominal Obesity Blood Triglycerides Ambient Particulate Matter Determinantes da Saúde e da Doença Saúde Pública |
description |
Background: Blood lipids and glucose levels dysregulation represent potential mechanisms intermediating the adverse cardiovascular effects of ambient particulate matter (PM) exposure. This study aims to estimate the effect of long-term PM10 exposure on blood lipids and glucose levels and to assess the potential mediation and/or modification action of abdominal obesity (AO) (waist-to-height ratio). Methods: Our study was based on 2,390 participants of the first Portuguese Health Examination Survey (INSEF, 2015) with available data on blood lipids and glucose parameters and living within a 30-km radius of an air quality monitoring station with available PM10 measurements. PM10 concentrations were acquired from the air quality monitoring network of the Portuguese Environment Agency. Generalized linear models were used to assess the effect of 1-year PM10 exposure on blood lipids and glucose levels. An interaction term was introduced in the models to test the modification action of AO. Results: We found an association between PM10 and non-fasting blood triglycerides (TG) after adjustment for age, sex, education, occupation, lifestyles-related variables and temperature but only in participants with AO. Per each 1 mg/m3 PM10 increment, there was a 1.84% (95% confidence interval: 0.02–3.69) increase in TG. For the remaining blood lipid and glucose parameters, no associations were found. Conclusions: Our study demonstrates that even at low levels of exposure, long-term PM10 exposure interacts with AO to increase blood TG. Our findings suggest that reducing both AO prevalence and PM10 below current standards would result in additional health benefits for the population. INSEF was developed as part of the Pre-defined project financed under the Public Health Initiatives Programme ‘Improvement of epidemiological health information to support public health decision and management in Portugal. Towards reduced inequalities, improved health and bilateral cooperation’ with a 1.500.000e Grant from Iceland, Liechtenstein and ... |
format |
Article in Journal/Newspaper |
author |
Gaio, Vânia Roquette, Rita Monteiro, Alexandra Ferreira, Joana Lopes, Diogo Dias, Carlos Matias Nunes, Baltazar |
author_facet |
Gaio, Vânia Roquette, Rita Monteiro, Alexandra Ferreira, Joana Lopes, Diogo Dias, Carlos Matias Nunes, Baltazar |
author_sort |
Gaio, Vânia |
title |
PM10 exposure interacts with abdominal obesity to increase blood triglycerides: a cross-sectional linkage study |
title_short |
PM10 exposure interacts with abdominal obesity to increase blood triglycerides: a cross-sectional linkage study |
title_full |
PM10 exposure interacts with abdominal obesity to increase blood triglycerides: a cross-sectional linkage study |
title_fullStr |
PM10 exposure interacts with abdominal obesity to increase blood triglycerides: a cross-sectional linkage study |
title_full_unstemmed |
PM10 exposure interacts with abdominal obesity to increase blood triglycerides: a cross-sectional linkage study |
title_sort |
pm10 exposure interacts with abdominal obesity to increase blood triglycerides: a cross-sectional linkage study |
publisher |
Oxford University Press/ European Public Health Association |
publishDate |
2021 |
url |
http://hdl.handle.net/10400.18/7834 https://doi.org/10.1093/eurpub/ckab190 |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
info:eu-repo/grantAgreement/FCT/OE/SFRH%2FBD%2F129426%2F2017/PT info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F50017%2F2020/PT info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F50017%2F2020/PT https://academic.oup.com/eurpub/advance-article-abstract/doi/10.1093/eurpub/ckab190/6425628?redirectedFrom=fulltext Eur J Public Health. 2022 Apr 1;32(2):281-288. doi:10.1093/eurpub/ckab190. Epub 2021 Nov 11. 1101-1262 http://hdl.handle.net/10400.18/7834 doi:10.1093/eurpub/ckab190 1464-360X |
op_rights |
openAccess |
op_doi |
https://doi.org/10.1093/eurpub/ckab190 |
container_title |
European Journal of Public Health |
container_volume |
32 |
container_issue |
2 |
container_start_page |
281 |
op_container_end_page |
288 |
_version_ |
1789333951392776192 |