Understanding the persistence of plague foci in Madagascar
Plague, a zoonosis caused by Yersinia pestis, is still found in Africa, Asia, and the Americas. Madagascar reports almost one third of the cases worldwide. Y. pestis can be encountered in three very different types of foci: urban, rural, and sylvatic. Flea vector and wild rodent host population dyna...
Published in: | PLoS Neglected Tropical Diseases |
---|---|
Main Authors: | , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
2013
|
Subjects: | |
Online Access: | http://prodinra.inra.fr/ft/7EA40F36-8A10-4192-A9BF-5E8983B38650 http://prodinra.inra.fr/record/286465 https://doi.org/10.1371/journal.pntd.0002382 |
id |
ftinraparis:oai:prodinra.inra.fr:286465 |
---|---|
record_format |
openpolar |
spelling |
ftinraparis:oai:prodinra.inra.fr:286465 2023-05-15T18:04:51+02:00 Understanding the persistence of plague foci in Madagascar Andrianaivoarimanana, Voahangy Kreppel, Katharina Elissa, Nohal Duplantier, Jean-Marc Carniel, Elisabeth Rajerison, Minoarisoa Jambou, Ronan 2013 application/pdf http://prodinra.inra.fr/ft/7EA40F36-8A10-4192-A9BF-5E8983B38650 http://prodinra.inra.fr/record/286465 https://doi.org/10.1371/journal.pntd.0002382 eng eng http://creativecommons.org/licenses/by-nd-nc/1.0/ CC-BY-ND-NC Plos Neglected Tropical Diseases (7), . (2013) rattus rattus peste Yersinia pestis madagascar ARTICLE 2013 ftinraparis https://doi.org/10.1371/journal.pntd.0002382 2015-11-03T23:26:48Z Plague, a zoonosis caused by Yersinia pestis, is still found in Africa, Asia, and the Americas. Madagascar reports almost one third of the cases worldwide. Y. pestis can be encountered in three very different types of foci: urban, rural, and sylvatic. Flea vector and wild rodent host population dynamics are tightly correlated with modulation of climatic conditions, an association that could be crucial for both the maintenance of foci and human plague epidemics. The black rat Rattus rattus, the main host of Y. pestis in Madagascar, is found to exhibit high resistance to plague in endemic areas, opposing the concept of high mortality rates among rats exposed to the infection. Also, endemic fleas could play an essential role in maintenance of the foci. This review discusses recent advances in the understanding of the role of these factors as well as human behavior in the persistence of plague in Madagascar. Article in Journal/Newspaper Rattus rattus Institut National de la Recherche Agronomique: ProdINRA PLoS Neglected Tropical Diseases 7 11 e2382 |
institution |
Open Polar |
collection |
Institut National de la Recherche Agronomique: ProdINRA |
op_collection_id |
ftinraparis |
language |
English |
topic |
rattus rattus peste Yersinia pestis madagascar |
spellingShingle |
rattus rattus peste Yersinia pestis madagascar Andrianaivoarimanana, Voahangy Kreppel, Katharina Elissa, Nohal Duplantier, Jean-Marc Carniel, Elisabeth Rajerison, Minoarisoa Jambou, Ronan Understanding the persistence of plague foci in Madagascar |
topic_facet |
rattus rattus peste Yersinia pestis madagascar |
description |
Plague, a zoonosis caused by Yersinia pestis, is still found in Africa, Asia, and the Americas. Madagascar reports almost one third of the cases worldwide. Y. pestis can be encountered in three very different types of foci: urban, rural, and sylvatic. Flea vector and wild rodent host population dynamics are tightly correlated with modulation of climatic conditions, an association that could be crucial for both the maintenance of foci and human plague epidemics. The black rat Rattus rattus, the main host of Y. pestis in Madagascar, is found to exhibit high resistance to plague in endemic areas, opposing the concept of high mortality rates among rats exposed to the infection. Also, endemic fleas could play an essential role in maintenance of the foci. This review discusses recent advances in the understanding of the role of these factors as well as human behavior in the persistence of plague in Madagascar. |
format |
Article in Journal/Newspaper |
author |
Andrianaivoarimanana, Voahangy Kreppel, Katharina Elissa, Nohal Duplantier, Jean-Marc Carniel, Elisabeth Rajerison, Minoarisoa Jambou, Ronan |
author_facet |
Andrianaivoarimanana, Voahangy Kreppel, Katharina Elissa, Nohal Duplantier, Jean-Marc Carniel, Elisabeth Rajerison, Minoarisoa Jambou, Ronan |
author_sort |
Andrianaivoarimanana, Voahangy |
title |
Understanding the persistence of plague foci in Madagascar |
title_short |
Understanding the persistence of plague foci in Madagascar |
title_full |
Understanding the persistence of plague foci in Madagascar |
title_fullStr |
Understanding the persistence of plague foci in Madagascar |
title_full_unstemmed |
Understanding the persistence of plague foci in Madagascar |
title_sort |
understanding the persistence of plague foci in madagascar |
publishDate |
2013 |
url |
http://prodinra.inra.fr/ft/7EA40F36-8A10-4192-A9BF-5E8983B38650 http://prodinra.inra.fr/record/286465 https://doi.org/10.1371/journal.pntd.0002382 |
genre |
Rattus rattus |
genre_facet |
Rattus rattus |
op_source |
Plos Neglected Tropical Diseases (7), . (2013) |
op_rights |
http://creativecommons.org/licenses/by-nd-nc/1.0/ |
op_rightsnorm |
CC-BY-ND-NC |
op_doi |
https://doi.org/10.1371/journal.pntd.0002382 |
container_title |
PLoS Neglected Tropical Diseases |
container_volume |
7 |
container_issue |
11 |
container_start_page |
e2382 |
_version_ |
1766176269636993024 |