Molecular epidemiology of rabies virus circulating in domestic animals in India
Not Available Rabies is a neglected viral zoonotic disease affecting humans, domestic and wild animals and is endemic in most parts of the India. Dog mediated rabies is more predominant than other forms of rabies and molecular epidemiology is poorly understood in both reservoir and susceptible hosts...
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ftindiancar:oai:krishi.icar.gov.in:123456789/19850 2023-05-15T14:57:41+02:00 Molecular epidemiology of rabies virus circulating in domestic animals in India Not Available Manjunatha Reddy GB Krishnappa S Vinayagamurthy B Singh R Singh KP Saminathan M Sajjanar B Rahman H 2018-07-17 http://krishi.icar.gov.in/jspui/handle/123456789/19850 English eng Springer publishers Not Available; Not Available 2347-3517 http://krishi.icar.gov.in/jspui/handle/123456789/19850 Animals Epidemiology India N-gene Phylogenetic analysis Rabies Research Paper 2018 ftindiancar 2022-03-19T18:22:57Z Not Available Rabies is a neglected viral zoonotic disease affecting humans, domestic and wild animals and is endemic in most parts of the India. Dog mediated rabies is more predominant than other forms of rabies and molecular epidemiology is poorly understood in both reservoir and susceptible hosts. In the present study, a total of 140 rabies suspected brain samples from different species of animals from different geographical regions of India were used. The samples were parallelly tested by direct fluorescent antibody test, reverse transcriptase PCR and real-time PCR. Thirty positive samples were subjected for partial nucleoprotein gene sequencing and phylogenetic analysis. On sequence and phylogenetic analysis, it was observed that all Indian rabies viruses belonged to classical rabies virus of genotype 1 of Lyssavirus and formed two distinct groups. The majority of isolates were in group-1 and are closely related to arctic/arctic like lineage, whereas group-II isolated are closely related to cosmopolitan lineage. These results indicated there is simultaneous existence of two distinct lineages of rabies viruses in Indian subcontinent. Further whole genome studies are needed for better understanding of molecular epidemiology of rabies virus circulating in animals for control and prevention of rabies in India. Not Available Report Arctic KRISHI Publication and Data Inventory Repository (Knowledge based Resources Information Systems Hub for Innovations in Agriculture - Indian Council of Agricultural Research, ICAR) Arctic Indian |
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Open Polar |
collection |
KRISHI Publication and Data Inventory Repository (Knowledge based Resources Information Systems Hub for Innovations in Agriculture - Indian Council of Agricultural Research, ICAR) |
op_collection_id |
ftindiancar |
language |
English |
topic |
Animals Epidemiology India N-gene Phylogenetic analysis Rabies |
spellingShingle |
Animals Epidemiology India N-gene Phylogenetic analysis Rabies Manjunatha Reddy GB Krishnappa S Vinayagamurthy B Singh R Singh KP Saminathan M Sajjanar B Rahman H Molecular epidemiology of rabies virus circulating in domestic animals in India |
topic_facet |
Animals Epidemiology India N-gene Phylogenetic analysis Rabies |
description |
Not Available Rabies is a neglected viral zoonotic disease affecting humans, domestic and wild animals and is endemic in most parts of the India. Dog mediated rabies is more predominant than other forms of rabies and molecular epidemiology is poorly understood in both reservoir and susceptible hosts. In the present study, a total of 140 rabies suspected brain samples from different species of animals from different geographical regions of India were used. The samples were parallelly tested by direct fluorescent antibody test, reverse transcriptase PCR and real-time PCR. Thirty positive samples were subjected for partial nucleoprotein gene sequencing and phylogenetic analysis. On sequence and phylogenetic analysis, it was observed that all Indian rabies viruses belonged to classical rabies virus of genotype 1 of Lyssavirus and formed two distinct groups. The majority of isolates were in group-1 and are closely related to arctic/arctic like lineage, whereas group-II isolated are closely related to cosmopolitan lineage. These results indicated there is simultaneous existence of two distinct lineages of rabies viruses in Indian subcontinent. Further whole genome studies are needed for better understanding of molecular epidemiology of rabies virus circulating in animals for control and prevention of rabies in India. Not Available |
format |
Report |
author |
Manjunatha Reddy GB Krishnappa S Vinayagamurthy B Singh R Singh KP Saminathan M Sajjanar B Rahman H |
author_facet |
Manjunatha Reddy GB Krishnappa S Vinayagamurthy B Singh R Singh KP Saminathan M Sajjanar B Rahman H |
author_sort |
Manjunatha Reddy GB |
title |
Molecular epidemiology of rabies virus circulating in domestic animals in India |
title_short |
Molecular epidemiology of rabies virus circulating in domestic animals in India |
title_full |
Molecular epidemiology of rabies virus circulating in domestic animals in India |
title_fullStr |
Molecular epidemiology of rabies virus circulating in domestic animals in India |
title_full_unstemmed |
Molecular epidemiology of rabies virus circulating in domestic animals in India |
title_sort |
molecular epidemiology of rabies virus circulating in domestic animals in india |
publisher |
Springer publishers |
publishDate |
2018 |
url |
http://krishi.icar.gov.in/jspui/handle/123456789/19850 |
geographic |
Arctic Indian |
geographic_facet |
Arctic Indian |
genre |
Arctic |
genre_facet |
Arctic |
op_relation |
Not Available; Not Available 2347-3517 http://krishi.icar.gov.in/jspui/handle/123456789/19850 |
_version_ |
1766329819217264640 |