Antidoting Effect of Vitamin K1 Supplementation on Difethialone Poisoned House Rat, Rattus rattus Linneaus
Not Available With the advent of second-generation anticoagulant rodenticides rodent management technology has substantially improved, since they provide sustainable control of rodents and are relatively safe to non-targets than the acute rodenticides. Due to their anticoagulant nature vitamin K1 re...
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Arid Zone Research Association of India
2006
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ftindiancar:oai:krishi.icar.gov.in:123456789/18959 2023-05-15T18:04:56+02:00 Antidoting Effect of Vitamin K1 Supplementation on Difethialone Poisoned House Rat, Rattus rattus Linneaus Not Available V. Chaudhary R. S. Tripathi 2006-01-01 http://krishi.icar.gov.in/jspui/handle/123456789/18959 English eng Arid Zone Research Association of India Not Available; Not Available 0570-1791 http://krishi.icar.gov.in/jspui/handle/123456789/18959 Rattus rattus Anticoagulants Difethialone Baits Vitamin K1 supplemented food Plain Food Research Paper 2006 ftindiancar 2022-03-05T18:20:19Z Not Available With the advent of second-generation anticoagulant rodenticides rodent management technology has substantially improved, since they provide sustainable control of rodents and are relatively safe to non-targets than the acute rodenticides. Due to their anticoagulant nature vitamin K1 regarded as an effective antidote for such rodenticides, Two dosages (1 and 2 mg/kg) of vitamin K1 supplementation for 5 and 15 days were given to house rat R. rattus fed on difethialone bait (0.0025%) for one day for studying the effect of antidoting on poisoned rats. The results indicated that the lower dosage could not reverse the anticoagulation process, however the period of mortality was considerably increased from 3-9 days (in control) to 4-11 and 11-22 days (5 and 15 days supplementation regime, respectively). However, when the vitamin K1 dosage was doubled and given for 15 days, antidoting was more pronounced due to reversal of anticoagulation process in 83% cases as five of the six rats became normal within a month of difethialone poisoning. Not Available Report Rattus rattus KRISHI Publication and Data Inventory Repository (Knowledge based Resources Information Systems Hub for Innovations in Agriculture - Indian Council of Agricultural Research, ICAR) |
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KRISHI Publication and Data Inventory Repository (Knowledge based Resources Information Systems Hub for Innovations in Agriculture - Indian Council of Agricultural Research, ICAR) |
op_collection_id |
ftindiancar |
language |
English |
topic |
Rattus rattus Anticoagulants Difethialone Baits Vitamin K1 supplemented food Plain Food |
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Rattus rattus Anticoagulants Difethialone Baits Vitamin K1 supplemented food Plain Food V. Chaudhary R. S. Tripathi Antidoting Effect of Vitamin K1 Supplementation on Difethialone Poisoned House Rat, Rattus rattus Linneaus |
topic_facet |
Rattus rattus Anticoagulants Difethialone Baits Vitamin K1 supplemented food Plain Food |
description |
Not Available With the advent of second-generation anticoagulant rodenticides rodent management technology has substantially improved, since they provide sustainable control of rodents and are relatively safe to non-targets than the acute rodenticides. Due to their anticoagulant nature vitamin K1 regarded as an effective antidote for such rodenticides, Two dosages (1 and 2 mg/kg) of vitamin K1 supplementation for 5 and 15 days were given to house rat R. rattus fed on difethialone bait (0.0025%) for one day for studying the effect of antidoting on poisoned rats. The results indicated that the lower dosage could not reverse the anticoagulation process, however the period of mortality was considerably increased from 3-9 days (in control) to 4-11 and 11-22 days (5 and 15 days supplementation regime, respectively). However, when the vitamin K1 dosage was doubled and given for 15 days, antidoting was more pronounced due to reversal of anticoagulation process in 83% cases as five of the six rats became normal within a month of difethialone poisoning. Not Available |
format |
Report |
author |
V. Chaudhary R. S. Tripathi |
author_facet |
V. Chaudhary R. S. Tripathi |
author_sort |
V. Chaudhary |
title |
Antidoting Effect of Vitamin K1 Supplementation on Difethialone Poisoned House Rat, Rattus rattus Linneaus |
title_short |
Antidoting Effect of Vitamin K1 Supplementation on Difethialone Poisoned House Rat, Rattus rattus Linneaus |
title_full |
Antidoting Effect of Vitamin K1 Supplementation on Difethialone Poisoned House Rat, Rattus rattus Linneaus |
title_fullStr |
Antidoting Effect of Vitamin K1 Supplementation on Difethialone Poisoned House Rat, Rattus rattus Linneaus |
title_full_unstemmed |
Antidoting Effect of Vitamin K1 Supplementation on Difethialone Poisoned House Rat, Rattus rattus Linneaus |
title_sort |
antidoting effect of vitamin k1 supplementation on difethialone poisoned house rat, rattus rattus linneaus |
publisher |
Arid Zone Research Association of India |
publishDate |
2006 |
url |
http://krishi.icar.gov.in/jspui/handle/123456789/18959 |
genre |
Rattus rattus |
genre_facet |
Rattus rattus |
op_relation |
Not Available; Not Available 0570-1791 http://krishi.icar.gov.in/jspui/handle/123456789/18959 |
_version_ |
1766176357743591424 |