Process intensification by microwave irradiation in immobilized-lipase catalysis in solvent-free synthesis of ethyl valerate
Valeric esters are a promising energy source and used in different industries ranging from biofuels, perfumes, food, flavors to pharmaceuticals. Ethyl valerate is one of the esters possessing all these attributes as an industrial chemical. In the current work an enzymatic route was examined using va...
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ftindianacasci:oai:repository.ias.ac.in:125380 2023-05-15T13:53:36+02:00 Process intensification by microwave irradiation in immobilized-lipase catalysis in solvent-free synthesis of ethyl valerate Bhavsar, Kalpesh V. Yadav, Ganapati D. 2018 http://repository.ias.ac.in/125380/ https://doi.org/10.1016/j.mcat.2018.09.019 unknown Elsevier Science Bhavsar, Kalpesh V. Yadav, Ganapati D. (2018) Process intensification by microwave irradiation in immobilized-lipase catalysis in solvent-free synthesis of ethyl valerate Molecular Catalysis, 461 . pp. 34-39. ISSN 2468-8231 TP Chemical technology Article PeerReviewed 2018 ftindianacasci https://doi.org/10.1016/j.mcat.2018.09.019 2022-02-05T18:16:38Z Valeric esters are a promising energy source and used in different industries ranging from biofuels, perfumes, food, flavors to pharmaceuticals. Ethyl valerate is one of the esters possessing all these attributes as an industrial chemical. In the current work an enzymatic route was examined using valeric acid and ethanol with commercially available lipases, namely, Lipozyme RM IM, Lipozyme TL IM and Novozyme 435 (Candida antarctica lipase B) under solvent fee condition and microwave irradiation. Novozym 435 could lead to 69.2% conversion of valeric acid at 50 °C using equimolar ratio of valeric acid and ethanol at enzyme loading of 10.06 g L−1 in 40 min under microwave irradiation. Lineweaver-Burk plot shows ternary complex mechanism with inhibition by ethanol. A reaction mechanism is proposed and kinetic rate equation derived. The enzyme is reusable. Article in Journal/Newspaper Antarc* Antarctica Indian Academy of Sciences: Publication of Fellows Molecular Catalysis 461 34 39 |
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Indian Academy of Sciences: Publication of Fellows |
op_collection_id |
ftindianacasci |
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unknown |
topic |
TP Chemical technology |
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TP Chemical technology Bhavsar, Kalpesh V. Yadav, Ganapati D. Process intensification by microwave irradiation in immobilized-lipase catalysis in solvent-free synthesis of ethyl valerate |
topic_facet |
TP Chemical technology |
description |
Valeric esters are a promising energy source and used in different industries ranging from biofuels, perfumes, food, flavors to pharmaceuticals. Ethyl valerate is one of the esters possessing all these attributes as an industrial chemical. In the current work an enzymatic route was examined using valeric acid and ethanol with commercially available lipases, namely, Lipozyme RM IM, Lipozyme TL IM and Novozyme 435 (Candida antarctica lipase B) under solvent fee condition and microwave irradiation. Novozym 435 could lead to 69.2% conversion of valeric acid at 50 °C using equimolar ratio of valeric acid and ethanol at enzyme loading of 10.06 g L−1 in 40 min under microwave irradiation. Lineweaver-Burk plot shows ternary complex mechanism with inhibition by ethanol. A reaction mechanism is proposed and kinetic rate equation derived. The enzyme is reusable. |
format |
Article in Journal/Newspaper |
author |
Bhavsar, Kalpesh V. Yadav, Ganapati D. |
author_facet |
Bhavsar, Kalpesh V. Yadav, Ganapati D. |
author_sort |
Bhavsar, Kalpesh V. |
title |
Process intensification by microwave irradiation in immobilized-lipase catalysis in solvent-free synthesis of ethyl valerate |
title_short |
Process intensification by microwave irradiation in immobilized-lipase catalysis in solvent-free synthesis of ethyl valerate |
title_full |
Process intensification by microwave irradiation in immobilized-lipase catalysis in solvent-free synthesis of ethyl valerate |
title_fullStr |
Process intensification by microwave irradiation in immobilized-lipase catalysis in solvent-free synthesis of ethyl valerate |
title_full_unstemmed |
Process intensification by microwave irradiation in immobilized-lipase catalysis in solvent-free synthesis of ethyl valerate |
title_sort |
process intensification by microwave irradiation in immobilized-lipase catalysis in solvent-free synthesis of ethyl valerate |
publisher |
Elsevier Science |
publishDate |
2018 |
url |
http://repository.ias.ac.in/125380/ https://doi.org/10.1016/j.mcat.2018.09.019 |
genre |
Antarc* Antarctica |
genre_facet |
Antarc* Antarctica |
op_relation |
Bhavsar, Kalpesh V. Yadav, Ganapati D. (2018) Process intensification by microwave irradiation in immobilized-lipase catalysis in solvent-free synthesis of ethyl valerate Molecular Catalysis, 461 . pp. 34-39. ISSN 2468-8231 |
op_doi |
https://doi.org/10.1016/j.mcat.2018.09.019 |
container_title |
Molecular Catalysis |
container_volume |
461 |
container_start_page |
34 |
op_container_end_page |
39 |
_version_ |
1766258793713238016 |