Micronutrient supplementation affects DNA methylation in male gonads with potential intergenerational epigenetic inheritance involving the embryonic development through glutamate receptor-associated genes
DNA methylation has an important role in intergenerational inheritance. An increasing number of studies have reported evidence of germline inheritance of DNA methylation induced by nutritional signals in mammals. Vitamins and minerals as micronutrients contribute to growth performance in vertebrates...
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Online Access: | https://hdl.handle.net/11250/3014630 https://doi.org/10.1186/s12864-022-08348-4 |
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ftimr:oai:imr.brage.unit.no:11250/3014630 2023-05-15T15:31:36+02:00 Micronutrient supplementation affects DNA methylation in male gonads with potential intergenerational epigenetic inheritance involving the embryonic development through glutamate receptor-associated genes Saito, Takaya Whatmore, Paul Taylor, John F. Fernandes, Jorge Manuel de Oliveira Adam, Anne-Catrin Tocher, Douglas R. Espe, Marit Skjærven, Kaja Helvik 2022 application/pdf https://hdl.handle.net/11250/3014630 https://doi.org/10.1186/s12864-022-08348-4 eng eng BMC Genomics. 2022, 23 (1), . urn:issn:1471-2164 https://hdl.handle.net/11250/3014630 https://doi.org/10.1186/s12864-022-08348-4 cristin:2025870 0 23 BMC Genomics 1 Peer reviewed Journal article 2022 ftimr https://doi.org/10.1186/s12864-022-08348-4 2022-09-07T22:41:47Z DNA methylation has an important role in intergenerational inheritance. An increasing number of studies have reported evidence of germline inheritance of DNA methylation induced by nutritional signals in mammals. Vitamins and minerals as micronutrients contribute to growth performance in vertebrates, including Atlantic salmon (Salmo salar), and also have a role in epigenetics as environmental factors that alter DNA methylation status. It is important to understand whether micronutrients in the paternal diet can influence the offspring through alterations of DNA methylation signatures in male germ cells. publishedVersion Article in Journal/Newspaper Atlantic salmon Salmo salar Institute for Marine Research: Brage IMR BMC Genomics 23 1 |
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Open Polar |
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Institute for Marine Research: Brage IMR |
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ftimr |
language |
English |
description |
DNA methylation has an important role in intergenerational inheritance. An increasing number of studies have reported evidence of germline inheritance of DNA methylation induced by nutritional signals in mammals. Vitamins and minerals as micronutrients contribute to growth performance in vertebrates, including Atlantic salmon (Salmo salar), and also have a role in epigenetics as environmental factors that alter DNA methylation status. It is important to understand whether micronutrients in the paternal diet can influence the offspring through alterations of DNA methylation signatures in male germ cells. publishedVersion |
format |
Article in Journal/Newspaper |
author |
Saito, Takaya Whatmore, Paul Taylor, John F. Fernandes, Jorge Manuel de Oliveira Adam, Anne-Catrin Tocher, Douglas R. Espe, Marit Skjærven, Kaja Helvik |
spellingShingle |
Saito, Takaya Whatmore, Paul Taylor, John F. Fernandes, Jorge Manuel de Oliveira Adam, Anne-Catrin Tocher, Douglas R. Espe, Marit Skjærven, Kaja Helvik Micronutrient supplementation affects DNA methylation in male gonads with potential intergenerational epigenetic inheritance involving the embryonic development through glutamate receptor-associated genes |
author_facet |
Saito, Takaya Whatmore, Paul Taylor, John F. Fernandes, Jorge Manuel de Oliveira Adam, Anne-Catrin Tocher, Douglas R. Espe, Marit Skjærven, Kaja Helvik |
author_sort |
Saito, Takaya |
title |
Micronutrient supplementation affects DNA methylation in male gonads with potential intergenerational epigenetic inheritance involving the embryonic development through glutamate receptor-associated genes |
title_short |
Micronutrient supplementation affects DNA methylation in male gonads with potential intergenerational epigenetic inheritance involving the embryonic development through glutamate receptor-associated genes |
title_full |
Micronutrient supplementation affects DNA methylation in male gonads with potential intergenerational epigenetic inheritance involving the embryonic development through glutamate receptor-associated genes |
title_fullStr |
Micronutrient supplementation affects DNA methylation in male gonads with potential intergenerational epigenetic inheritance involving the embryonic development through glutamate receptor-associated genes |
title_full_unstemmed |
Micronutrient supplementation affects DNA methylation in male gonads with potential intergenerational epigenetic inheritance involving the embryonic development through glutamate receptor-associated genes |
title_sort |
micronutrient supplementation affects dna methylation in male gonads with potential intergenerational epigenetic inheritance involving the embryonic development through glutamate receptor-associated genes |
publishDate |
2022 |
url |
https://hdl.handle.net/11250/3014630 https://doi.org/10.1186/s12864-022-08348-4 |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_source |
0 23 BMC Genomics 1 |
op_relation |
BMC Genomics. 2022, 23 (1), . urn:issn:1471-2164 https://hdl.handle.net/11250/3014630 https://doi.org/10.1186/s12864-022-08348-4 cristin:2025870 |
op_doi |
https://doi.org/10.1186/s12864-022-08348-4 |
container_title |
BMC Genomics |
container_volume |
23 |
container_issue |
1 |
_version_ |
1766362128189489152 |