Diet affects the redox system in developing Atlantic cod(Gadus morhua) larvae
- The growth and development of marine fish larvae fed copepods is superior to those fed rotifers, but the underlying molecular reasons for this are unclear. In the following study we compared the effects of such diets on redox regulation pathways during development of Atlantic cod (Gadus morhua) la...
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Online Access: | http://hdl.handle.net/11250/285403 https://doi.org/10.1016/j.redox.2015.06.003 |
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ftimr:oai:imr.brage.unit.no:11250/285403 2023-05-15T15:27:13+02:00 Diet affects the redox system in developing Atlantic cod(Gadus morhua) larvae Penglase, Samuel Edvardsen, Rolf Furmanek, Tomasz Rønnestad, Ivar Karlsen, Ørjan van der Meeren, Terje Hamre, Kristin 2015-06-22T13:24:40Z application/pdf http://hdl.handle.net/11250/285403 https://doi.org/10.1016/j.redox.2015.06.003 eng eng Elsevier http://www.sciencedirect.com/science/article/pii/S2213231715000543 Norges forskningsråd: 199482 Redox Biology 2015, 5:308-318 urn:issn:2213-2317 http://hdl.handle.net/11250/285403 https://doi.org/10.1016/j.redox.2015.06.003 cristin:1249427 Navngivelse-IngenBearbeidelse 3.0 Norge http://creativecommons.org/licenses/by-nd/3.0/no/ CC-BY-ND 308-318 5 Redox biology Journal article Peer reviewed 2015 ftimr https://doi.org/10.1016/j.redox.2015.06.003 2021-09-23T20:15:41Z - The growth and development of marine fish larvae fed copepods is superior to those fed rotifers, but the underlying molecular reasons for this are unclear. In the following study we compared the effects of such diets on redox regulation pathways during development of Atlantic cod (Gadus morhua) larvae. Cod larvae were fed a control diet of copepods or the typical rotifer/Artemia diet commonly used in commercial marine fish hatcheries, from first feeding until after metamorphosis. The oxidised and reduced glutathione levels, the redox potential, and the mRNA expression of 100 genes in redox system pathways were then compared between treatments during larval development. We found that rotifer/Artemia-fed cod larvae had lower levels of oxidised glutathione, a more reduced redox potential, and altered expression of approximately half of the redox system genes when compared to copepod-fed larvae. This rotifer/Artemia diet-induced differential regulation of the redox system was greatest during periods of suboptimal growth. Upregulation of the oxidative stress response transcription factor, nrf2, and NRF2 target genes in rotifer/Artemia fed larvae suggest this diet induced an NRF2-mediated oxidative stress response. Overall, the data demonstrate that nutritional intake plays a role in regulating the redox system in developing fish larvae. This may be a factor in dietary-induced differences observed in larval growth. Article in Journal/Newspaper atlantic cod Gadus morhua Copepods Rotifer Institute for Marine Research: Brage IMR Redox Biology 5 308 318 |
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Open Polar |
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Institute for Marine Research: Brage IMR |
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ftimr |
language |
English |
description |
- The growth and development of marine fish larvae fed copepods is superior to those fed rotifers, but the underlying molecular reasons for this are unclear. In the following study we compared the effects of such diets on redox regulation pathways during development of Atlantic cod (Gadus morhua) larvae. Cod larvae were fed a control diet of copepods or the typical rotifer/Artemia diet commonly used in commercial marine fish hatcheries, from first feeding until after metamorphosis. The oxidised and reduced glutathione levels, the redox potential, and the mRNA expression of 100 genes in redox system pathways were then compared between treatments during larval development. We found that rotifer/Artemia-fed cod larvae had lower levels of oxidised glutathione, a more reduced redox potential, and altered expression of approximately half of the redox system genes when compared to copepod-fed larvae. This rotifer/Artemia diet-induced differential regulation of the redox system was greatest during periods of suboptimal growth. Upregulation of the oxidative stress response transcription factor, nrf2, and NRF2 target genes in rotifer/Artemia fed larvae suggest this diet induced an NRF2-mediated oxidative stress response. Overall, the data demonstrate that nutritional intake plays a role in regulating the redox system in developing fish larvae. This may be a factor in dietary-induced differences observed in larval growth. |
format |
Article in Journal/Newspaper |
author |
Penglase, Samuel Edvardsen, Rolf Furmanek, Tomasz Rønnestad, Ivar Karlsen, Ørjan van der Meeren, Terje Hamre, Kristin |
spellingShingle |
Penglase, Samuel Edvardsen, Rolf Furmanek, Tomasz Rønnestad, Ivar Karlsen, Ørjan van der Meeren, Terje Hamre, Kristin Diet affects the redox system in developing Atlantic cod(Gadus morhua) larvae |
author_facet |
Penglase, Samuel Edvardsen, Rolf Furmanek, Tomasz Rønnestad, Ivar Karlsen, Ørjan van der Meeren, Terje Hamre, Kristin |
author_sort |
Penglase, Samuel |
title |
Diet affects the redox system in developing Atlantic cod(Gadus morhua) larvae |
title_short |
Diet affects the redox system in developing Atlantic cod(Gadus morhua) larvae |
title_full |
Diet affects the redox system in developing Atlantic cod(Gadus morhua) larvae |
title_fullStr |
Diet affects the redox system in developing Atlantic cod(Gadus morhua) larvae |
title_full_unstemmed |
Diet affects the redox system in developing Atlantic cod(Gadus morhua) larvae |
title_sort |
diet affects the redox system in developing atlantic cod(gadus morhua) larvae |
publisher |
Elsevier |
publishDate |
2015 |
url |
http://hdl.handle.net/11250/285403 https://doi.org/10.1016/j.redox.2015.06.003 |
genre |
atlantic cod Gadus morhua Copepods Rotifer |
genre_facet |
atlantic cod Gadus morhua Copepods Rotifer |
op_source |
308-318 5 Redox biology |
op_relation |
http://www.sciencedirect.com/science/article/pii/S2213231715000543 Norges forskningsråd: 199482 Redox Biology 2015, 5:308-318 urn:issn:2213-2317 http://hdl.handle.net/11250/285403 https://doi.org/10.1016/j.redox.2015.06.003 cristin:1249427 |
op_rights |
Navngivelse-IngenBearbeidelse 3.0 Norge http://creativecommons.org/licenses/by-nd/3.0/no/ |
op_rightsnorm |
CC-BY-ND |
op_doi |
https://doi.org/10.1016/j.redox.2015.06.003 |
container_title |
Redox Biology |
container_volume |
5 |
container_start_page |
308 |
op_container_end_page |
318 |
_version_ |
1766357673262972928 |