Oil from transgenic Camelina sativa containing over 25 % n-3 long-chain PUFA as the major lipid source in feed for Atlantic salmon (Salmo salar)
Facing a bottleneck in the growth of aquaculture, and a gap in the supply and demand of the highly beneficial n-3 long-chain PUFA (LC-PUFA), sustainable alternatives to traditional marine-based feeds are required. Therefore, in the present trial, a novel oil obtained from a genetically engineered oi...
Published in: | British Journal of Nutrition |
---|---|
Main Authors: | , , , , , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
2018
|
Subjects: | |
Online Access: | http://hdl.handle.net/11250/2588988 https://doi.org/10.1017/S0007114518001125 |
id |
ftimr:oai:imr.brage.unit.no:11250/2588988 |
---|---|
record_format |
openpolar |
spelling |
ftimr:oai:imr.brage.unit.no:11250/2588988 2023-05-15T15:31:50+02:00 Oil from transgenic Camelina sativa containing over 25 % n-3 long-chain PUFA as the major lipid source in feed for Atlantic salmon (Salmo salar) Betancor, Mónica B. Li, Keshuai Bucerzan, Valentin S. Sprague, Matthew Sayanova, Olga Usher, Sarah Han, Lihua Norambuena, Fernando Torrissen, Ole Napier, Johnathan A. Tocher, Douglas R. Olsen, Rolf Erik 2018 application/pdf http://hdl.handle.net/11250/2588988 https://doi.org/10.1017/S0007114518001125 eng eng Norges forskningsråd: 245327 British Journal of Nutrition. 2018, 119 (12), 1378-1392. urn:issn:0007-1145 http://hdl.handle.net/11250/2588988 https://doi.org/10.1017/S0007114518001125 cristin:1595280 1378-1392 119 British Journal of Nutrition 12 Journal article Peer reviewed 2018 ftimr https://doi.org/10.1017/S0007114518001125 2021-09-23T20:15:57Z Facing a bottleneck in the growth of aquaculture, and a gap in the supply and demand of the highly beneficial n-3 long-chain PUFA (LC-PUFA), sustainable alternatives to traditional marine-based feeds are required. Therefore, in the present trial, a novel oil obtained from a genetically engineered oilseed crop, Camelina sativa, that supplied over 25 % n-3 LC-PUFA was tested as a sole dietary-added lipid source in Atlantic salmon (Salmo salar) feed. Three groups of fish were fed three experimental diets for 12 weeks with the same basal composition and containing 20 % added oil supplied by either a blend of fish oil and rapeseed oil (1:3) (COM) reflecting current commercial formulations, wild-type Camelina oil (WCO) or the novel transgenic Camelina oil (TCO). There were no negative effects on the growth, survival rate or health of the fish. The whole fish and flesh n-3 LC-PUFA levels were highest in fish fed TCO, with levels more than 2-fold higher compared with those of fish fed the COM and WCO diets, respectively. Diet TCO had no negative impacts on the evaluated immune and physiological parameters of head kidney monocytes. The transcriptomic responses of liver and mid-intestine showed only mild effects on metabolism genes. Overall, the results clearly indicated that the oil from transgenic Camelina was highly efficient in supplying n-3 LC-PUFA providing levels double that obtained with a current commercial standard, and similar to those a decade ago before substantial dietary fishmeal and oil replacement. acceptedVersion Article in Journal/Newspaper Atlantic salmon Salmo salar Institute for Marine Research: Brage IMR British Journal of Nutrition 119 12 1378 1392 |
institution |
Open Polar |
collection |
Institute for Marine Research: Brage IMR |
op_collection_id |
ftimr |
language |
English |
description |
Facing a bottleneck in the growth of aquaculture, and a gap in the supply and demand of the highly beneficial n-3 long-chain PUFA (LC-PUFA), sustainable alternatives to traditional marine-based feeds are required. Therefore, in the present trial, a novel oil obtained from a genetically engineered oilseed crop, Camelina sativa, that supplied over 25 % n-3 LC-PUFA was tested as a sole dietary-added lipid source in Atlantic salmon (Salmo salar) feed. Three groups of fish were fed three experimental diets for 12 weeks with the same basal composition and containing 20 % added oil supplied by either a blend of fish oil and rapeseed oil (1:3) (COM) reflecting current commercial formulations, wild-type Camelina oil (WCO) or the novel transgenic Camelina oil (TCO). There were no negative effects on the growth, survival rate or health of the fish. The whole fish and flesh n-3 LC-PUFA levels were highest in fish fed TCO, with levels more than 2-fold higher compared with those of fish fed the COM and WCO diets, respectively. Diet TCO had no negative impacts on the evaluated immune and physiological parameters of head kidney monocytes. The transcriptomic responses of liver and mid-intestine showed only mild effects on metabolism genes. Overall, the results clearly indicated that the oil from transgenic Camelina was highly efficient in supplying n-3 LC-PUFA providing levels double that obtained with a current commercial standard, and similar to those a decade ago before substantial dietary fishmeal and oil replacement. acceptedVersion |
format |
Article in Journal/Newspaper |
author |
Betancor, Mónica B. Li, Keshuai Bucerzan, Valentin S. Sprague, Matthew Sayanova, Olga Usher, Sarah Han, Lihua Norambuena, Fernando Torrissen, Ole Napier, Johnathan A. Tocher, Douglas R. Olsen, Rolf Erik |
spellingShingle |
Betancor, Mónica B. Li, Keshuai Bucerzan, Valentin S. Sprague, Matthew Sayanova, Olga Usher, Sarah Han, Lihua Norambuena, Fernando Torrissen, Ole Napier, Johnathan A. Tocher, Douglas R. Olsen, Rolf Erik Oil from transgenic Camelina sativa containing over 25 % n-3 long-chain PUFA as the major lipid source in feed for Atlantic salmon (Salmo salar) |
author_facet |
Betancor, Mónica B. Li, Keshuai Bucerzan, Valentin S. Sprague, Matthew Sayanova, Olga Usher, Sarah Han, Lihua Norambuena, Fernando Torrissen, Ole Napier, Johnathan A. Tocher, Douglas R. Olsen, Rolf Erik |
author_sort |
Betancor, Mónica B. |
title |
Oil from transgenic Camelina sativa containing over 25 % n-3 long-chain PUFA as the major lipid source in feed for Atlantic salmon (Salmo salar) |
title_short |
Oil from transgenic Camelina sativa containing over 25 % n-3 long-chain PUFA as the major lipid source in feed for Atlantic salmon (Salmo salar) |
title_full |
Oil from transgenic Camelina sativa containing over 25 % n-3 long-chain PUFA as the major lipid source in feed for Atlantic salmon (Salmo salar) |
title_fullStr |
Oil from transgenic Camelina sativa containing over 25 % n-3 long-chain PUFA as the major lipid source in feed for Atlantic salmon (Salmo salar) |
title_full_unstemmed |
Oil from transgenic Camelina sativa containing over 25 % n-3 long-chain PUFA as the major lipid source in feed for Atlantic salmon (Salmo salar) |
title_sort |
oil from transgenic camelina sativa containing over 25 % n-3 long-chain pufa as the major lipid source in feed for atlantic salmon (salmo salar) |
publishDate |
2018 |
url |
http://hdl.handle.net/11250/2588988 https://doi.org/10.1017/S0007114518001125 |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_source |
1378-1392 119 British Journal of Nutrition 12 |
op_relation |
Norges forskningsråd: 245327 British Journal of Nutrition. 2018, 119 (12), 1378-1392. urn:issn:0007-1145 http://hdl.handle.net/11250/2588988 https://doi.org/10.1017/S0007114518001125 cristin:1595280 |
op_doi |
https://doi.org/10.1017/S0007114518001125 |
container_title |
British Journal of Nutrition |
container_volume |
119 |
container_issue |
12 |
container_start_page |
1378 |
op_container_end_page |
1392 |
_version_ |
1766362351947218944 |