"Islands of divergence" in the Atlantic cod genome represent polymorphic chromosomal rearrangements
- In several species genetic differentiation across environmental gradients or between geographically separate populations has been reported to center at “genomic islands of divergence,” resulting in heterogeneous differentiation patterns across genomes. Here, genomic regions of elevated divergence...
Published in: | Genome Biology and Evolution |
---|---|
Main Authors: | , , , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Oxford Journals
2016
|
Subjects: | |
Online Access: | http://hdl.handle.net/11250/2398368 https://doi.org/10.1093/gbe/evw057 |
id |
ftimr:oai:imr.brage.unit.no:11250/2398368 |
---|---|
record_format |
openpolar |
spelling |
ftimr:oai:imr.brage.unit.no:11250/2398368 2023-05-15T15:27:16+02:00 "Islands of divergence" in the Atlantic cod genome represent polymorphic chromosomal rearrangements Sodeland, Marte Jorde, Per Erik Lien, Sigbjørn Jentoft, Sissel Berg, Paul Ragnar Grove, Harald Kent, Matthew Peter Arnyasi, Mariann Olsen, Esben Moland Knutsen, Halvor 2016-07-26T11:45:46Z application/pdf http://hdl.handle.net/11250/2398368 https://doi.org/10.1093/gbe/evw057 eng eng Oxford Journals Genome Biology and Evolution 2016, 8(4):1012-1022 urn:issn:1759-6653 http://hdl.handle.net/11250/2398368 https://doi.org/10.1093/gbe/evw057 cristin:1347169 Navngivelse-DelPåSammeVilkår 3.0 Norge http://creativecommons.org/licenses/by-sa/3.0/no/ CC-BY-SA 1012-1022 8 Genome Biology and Evolution 4 Journal article Peer reviewed 2016 ftimr https://doi.org/10.1093/gbe/evw057 2021-09-23T20:16:06Z - In several species genetic differentiation across environmental gradients or between geographically separate populations has been reported to center at “genomic islands of divergence,” resulting in heterogeneous differentiation patterns across genomes. Here, genomic regions of elevated divergence were observed on three chromosomes of the highly mobile fish Atlantic cod (Gadus morhua) within geographically fine-scaled coastal areas. The “genomic islands” extended at least 5, 9.5, and 13 megabases on linkage groups 2, 7, and 12, respectively, and coincided with large blocks of linkage disequilibrium. For each of these three chromosomes, pairs of segregating, highly divergent alleles were identified, with little or no gene exchange between them. These patterns of recombination and divergence mirror genomic signatures previously described for large polymorphic inversions, which have been shown to repress recombination across extensive chromosomal segments. The lack of genetic exchange permits divergence between noninverted and inverted chromosomes in spite of gene flow. For the rearrangements on linkage groups 2 and 12, allelic frequency shifts between coastal and oceanic environments suggest a role in ecological adaptation, in agreement with recently reported associations between molecular variation within these genomic regions and temperature, oxygen, and salinity levels. Elevated genetic differentiation in these genomic regions has previously been described on both sides of the Atlantic Ocean, and we therefore suggest that these polymorphisms are involved in adaptive divergence across the species distributional range. Article in Journal/Newspaper atlantic cod Gadus morhua Institute for Marine Research: Brage IMR Genome Biology and Evolution 8 4 1012 1022 |
institution |
Open Polar |
collection |
Institute for Marine Research: Brage IMR |
op_collection_id |
ftimr |
language |
English |
description |
- In several species genetic differentiation across environmental gradients or between geographically separate populations has been reported to center at “genomic islands of divergence,” resulting in heterogeneous differentiation patterns across genomes. Here, genomic regions of elevated divergence were observed on three chromosomes of the highly mobile fish Atlantic cod (Gadus morhua) within geographically fine-scaled coastal areas. The “genomic islands” extended at least 5, 9.5, and 13 megabases on linkage groups 2, 7, and 12, respectively, and coincided with large blocks of linkage disequilibrium. For each of these three chromosomes, pairs of segregating, highly divergent alleles were identified, with little or no gene exchange between them. These patterns of recombination and divergence mirror genomic signatures previously described for large polymorphic inversions, which have been shown to repress recombination across extensive chromosomal segments. The lack of genetic exchange permits divergence between noninverted and inverted chromosomes in spite of gene flow. For the rearrangements on linkage groups 2 and 12, allelic frequency shifts between coastal and oceanic environments suggest a role in ecological adaptation, in agreement with recently reported associations between molecular variation within these genomic regions and temperature, oxygen, and salinity levels. Elevated genetic differentiation in these genomic regions has previously been described on both sides of the Atlantic Ocean, and we therefore suggest that these polymorphisms are involved in adaptive divergence across the species distributional range. |
format |
Article in Journal/Newspaper |
author |
Sodeland, Marte Jorde, Per Erik Lien, Sigbjørn Jentoft, Sissel Berg, Paul Ragnar Grove, Harald Kent, Matthew Peter Arnyasi, Mariann Olsen, Esben Moland Knutsen, Halvor |
spellingShingle |
Sodeland, Marte Jorde, Per Erik Lien, Sigbjørn Jentoft, Sissel Berg, Paul Ragnar Grove, Harald Kent, Matthew Peter Arnyasi, Mariann Olsen, Esben Moland Knutsen, Halvor "Islands of divergence" in the Atlantic cod genome represent polymorphic chromosomal rearrangements |
author_facet |
Sodeland, Marte Jorde, Per Erik Lien, Sigbjørn Jentoft, Sissel Berg, Paul Ragnar Grove, Harald Kent, Matthew Peter Arnyasi, Mariann Olsen, Esben Moland Knutsen, Halvor |
author_sort |
Sodeland, Marte |
title |
"Islands of divergence" in the Atlantic cod genome represent polymorphic chromosomal rearrangements |
title_short |
"Islands of divergence" in the Atlantic cod genome represent polymorphic chromosomal rearrangements |
title_full |
"Islands of divergence" in the Atlantic cod genome represent polymorphic chromosomal rearrangements |
title_fullStr |
"Islands of divergence" in the Atlantic cod genome represent polymorphic chromosomal rearrangements |
title_full_unstemmed |
"Islands of divergence" in the Atlantic cod genome represent polymorphic chromosomal rearrangements |
title_sort |
"islands of divergence" in the atlantic cod genome represent polymorphic chromosomal rearrangements |
publisher |
Oxford Journals |
publishDate |
2016 |
url |
http://hdl.handle.net/11250/2398368 https://doi.org/10.1093/gbe/evw057 |
genre |
atlantic cod Gadus morhua |
genre_facet |
atlantic cod Gadus morhua |
op_source |
1012-1022 8 Genome Biology and Evolution 4 |
op_relation |
Genome Biology and Evolution 2016, 8(4):1012-1022 urn:issn:1759-6653 http://hdl.handle.net/11250/2398368 https://doi.org/10.1093/gbe/evw057 cristin:1347169 |
op_rights |
Navngivelse-DelPåSammeVilkår 3.0 Norge http://creativecommons.org/licenses/by-sa/3.0/no/ |
op_rightsnorm |
CC-BY-SA |
op_doi |
https://doi.org/10.1093/gbe/evw057 |
container_title |
Genome Biology and Evolution |
container_volume |
8 |
container_issue |
4 |
container_start_page |
1012 |
op_container_end_page |
1022 |
_version_ |
1766357718775365632 |