Lysozyme Inhibitors as Tools for Lysozyme Profiling: Identification and Antibacterial Function of Lysozymes in the Hemolymph of the Blue Mussel

• Published in: Molecules
• Main Authors: Vanderkelen, Lise, Van Herreweghe, Joris M., Michiels, Chris W.
• Format: Article in Journal/Newspaper
• Language: English
• Published: Multidisciplinary Digital Publishing Institute (MDPI) 2023
• Subjects: Science & Technology; Life Sciences & Biomedicine; Physical Sciences; Biochemistry & Molecular Biology; Chemistry; Multidisciplinary; lysozyme; lysozyme inhibitor; innate immunity; antibacterial activity; bivalves; ESCHERICHIA-COLI; SEQUENCE; Animals; Muramidase; Mytilus edulis; Escherichia coli; Hemolymph; Anti-Bacterial Agents; Immunity; Innate; Phylogeny; 0304 Medicinal and Biomolecular Chemistry; 0305 Organic Chemistry; 0307 Theoretical and Computational Chemistry; Organic Chemistry; 3404 Medicinal and biomolecular chemistry; 3405 Organic chemistry; Norway; Tromso
• Online Access: https://lirias.kuleuven.be/handle/20.500.12942/729175; https://hdl.handle.net/20.500.12942/729175; https://lirias.kuleuven.be/retrieve/733951; https://doi.org/10.3390/molecules28207071; https://pubmed.ncbi.nlm.nih.gov/37894549

Lysozymes are universal components of the innate immune system of animals that kill bacteria by hydrolyzing their main cell wall polymer, peptidoglycan. Three main families of lysozyme have been identified, designated as chicken (c)-, goose (g)- and invertebrate (i)-type. In response, bacteria have...