Efficacy of synthetic and biological DMARDs: a systematic literature review informing the 2022 update of the EULAR recommendations for the management of rheumatoid arthritis

• Published in: Annals of the Rheumatic Diseases
• Main Authors: Kerschbaumer, Andreas, Sepriano, Alexandre, Bergstra, Sytske Anne, Smolen, Josef S., van der Heijde, Desiree, Caporali, Roberto, Edwards, Christopher John, Verschueren, Patrick, de Souza, Savia, Pope, Janet E., Takeuchi, Tsutomu, Hyrich, Kimme L., Winthrop, Kevin L., Aletaha, Daniel, Stamm, Tanja A., Schoones, Jan W., Landewe, Robert B.M.
• Format: Article in Journal/Newspaper
• Language: English
• Published: BMJ Publishing Group 2023
• Subjects: Science & Technology; Life Sciences & Biomedicine; Rheumatology; rheumatoid arthritis; DMARDs (synthetic); anti-TNF; outcomes research; MEDIATED INFLAMMATORY DISEASES; MODIFYING ANTIRHEUMATIC DRUGS; NECROSIS-FACTOR INHIBITOR; OPEN-LABEL; AMERICAN-COLLEGE; STANDARD THERAPY; ARCTIC REWIND; DOUBLE-BLIND; PHASE 4; REMISSION; Humans; Glucocorticoids; Biological Products; Antirheumatic Agents; Arthritis; Rheumatoid; Methotrexate; Biosimilar Pharmaceuticals; Janus Kinase Inhibitors; 1103 Clinical Sciences; 1107 Immunology; 1117 Public Health and Health Services; Arthritis & Rheumatology; 3202 Clinical sciences; 3204 Immunology; Arctic; Janus
• Online Access: https://lirias.kuleuven.be/handle/20.500.12942/711298; https://hdl.handle.net/20.500.12942/711298; https://doi.org/10.1136/ard-2022-223365; https://pubmed.ncbi.nlm.nih.gov/36368906

OBJECTIVES: To update the evidence on efficacy of DMARDs (disease-modifying antirheumatic drugs) and inform the taskforce of the 2022 update of the European Alliance of Associations for Rheumatology (EULAR) recommendations for management of rheumatoid arthritis (RA). METHODS: This systematic literat...