Serum 25-hydroxyvitamin D concentrations in 16-year-old Icelandic adolescent and its association with bone mineral density
Objective: The aim of the study was to assess the potential association between serum 25-hydroxyvitamin D (25(OH)D) and whole-body bone mineral density (BMD) among 16-year-old adolescents and to study the prevalence of 25(OH)D insufficiency, defined as concentration under 50 nmol/l. Design: A cross-...
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Online Access: | https://hdl.handle.net/11250/2676002 https://doi.org/10.1017/S1368980019004142 |
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fthsvestlandet:oai:hvlopen.brage.unit.no:11250/2676002 2024-03-03T08:45:44+00:00 Serum 25-hydroxyvitamin D concentrations in 16-year-old Icelandic adolescent and its association with bone mineral density Guðmundsdóttir, Sigríður Lára Hrafnkelsson, Hannes Sigurðsson, Emil Lárus Johannsson, Erlingur 2020 application/pdf https://hdl.handle.net/11250/2676002 https://doi.org/10.1017/S1368980019004142 eng eng Gudmundsdottir, S. L., Hrafnkelsson, H., Sigurdsson, E. L., & Johannsson, E. (2020). Serum 25-hydroxyvitamin D concentrations in 16-year-old Icelandic adolescent and its association with bone mineral density. Public Health Nutrition, 23(8), 1329-1333. urn:issn:1368-9800 https://hdl.handle.net/11250/2676002 https://doi.org/10.1017/S1368980019004142 cristin:1820880 Navngivelse 4.0 Internasjonal http://creativecommons.org/licenses/by/4.0/deed.no © The Author(s) 1329-1333 23 Public Health Nutrition 8 25-hydroxyvitamin D Bone mineral density Adolescent Cross sectional Vitamin D Peer reviewed Journal article 2020 fthsvestlandet https://doi.org/10.1017/S1368980019004142 2024-02-02T12:40:28Z Objective: The aim of the study was to assess the potential association between serum 25-hydroxyvitamin D (25(OH)D) and whole-body bone mineral density (BMD) among 16-year-old adolescents and to study the prevalence of 25(OH)D insufficiency, defined as concentration under 50 nmol/l. Design: A cross-sectional study. Setting: Reykjavik, Iceland, latitude 64°08′N. Measurements took place in the Icelandic Heart Association's research lab during April–June 2015. Participants: In total, 411 students in Reykjavik, Iceland, were invited to participate, 315 accepted the invitation (76·6 %) and 289 had valid data (mainly Caucasian). Results: 25(OH)D < 50 nmol/l was observed in 70 % of girls and 66·7 % of boys. 25(OH)D ≥ 50 nmol/l was significantly associated with higher whole-body BMD after adjusting for the influence of sex, height, fat mass and lean mass. A linear relationship between 25(OH)D and whole-body BMD was significant for 25(OH)D < 50 nmol/l (n 199, P < 0·05) but NS for 25(OH)D ≥ 50 nmol/l (n 86, P = 0·48). Conclusions: Our results are in line with some but not all previous studies on the relationship between BMD and 25(OH)D in adolescents. The observed difference in BMD between those with above v. below a 25(OH)D concentration of 50 nmol/l was of about a fifth of one SD, which may have a clinical relevance as one SD decrease in volumetric BMD has been associated with a 89 % increase in 2 years risk of fracture. Icelandic adolescents should be encouraged to increase their vitamin D intake as it is possible that their current intake is insufficient to achieve optimal peak bone mass. publishedVersion Article in Journal/Newspaper Iceland Høgskulen på Vestlandet: HVL Open Public Health Nutrition 23 8 1329 1333 |
institution |
Open Polar |
collection |
Høgskulen på Vestlandet: HVL Open |
op_collection_id |
fthsvestlandet |
language |
English |
topic |
25-hydroxyvitamin D Bone mineral density Adolescent Cross sectional Vitamin D |
spellingShingle |
25-hydroxyvitamin D Bone mineral density Adolescent Cross sectional Vitamin D Guðmundsdóttir, Sigríður Lára Hrafnkelsson, Hannes Sigurðsson, Emil Lárus Johannsson, Erlingur Serum 25-hydroxyvitamin D concentrations in 16-year-old Icelandic adolescent and its association with bone mineral density |
topic_facet |
25-hydroxyvitamin D Bone mineral density Adolescent Cross sectional Vitamin D |
description |
Objective: The aim of the study was to assess the potential association between serum 25-hydroxyvitamin D (25(OH)D) and whole-body bone mineral density (BMD) among 16-year-old adolescents and to study the prevalence of 25(OH)D insufficiency, defined as concentration under 50 nmol/l. Design: A cross-sectional study. Setting: Reykjavik, Iceland, latitude 64°08′N. Measurements took place in the Icelandic Heart Association's research lab during April–June 2015. Participants: In total, 411 students in Reykjavik, Iceland, were invited to participate, 315 accepted the invitation (76·6 %) and 289 had valid data (mainly Caucasian). Results: 25(OH)D < 50 nmol/l was observed in 70 % of girls and 66·7 % of boys. 25(OH)D ≥ 50 nmol/l was significantly associated with higher whole-body BMD after adjusting for the influence of sex, height, fat mass and lean mass. A linear relationship between 25(OH)D and whole-body BMD was significant for 25(OH)D < 50 nmol/l (n 199, P < 0·05) but NS for 25(OH)D ≥ 50 nmol/l (n 86, P = 0·48). Conclusions: Our results are in line with some but not all previous studies on the relationship between BMD and 25(OH)D in adolescents. The observed difference in BMD between those with above v. below a 25(OH)D concentration of 50 nmol/l was of about a fifth of one SD, which may have a clinical relevance as one SD decrease in volumetric BMD has been associated with a 89 % increase in 2 years risk of fracture. Icelandic adolescents should be encouraged to increase their vitamin D intake as it is possible that their current intake is insufficient to achieve optimal peak bone mass. publishedVersion |
format |
Article in Journal/Newspaper |
author |
Guðmundsdóttir, Sigríður Lára Hrafnkelsson, Hannes Sigurðsson, Emil Lárus Johannsson, Erlingur |
author_facet |
Guðmundsdóttir, Sigríður Lára Hrafnkelsson, Hannes Sigurðsson, Emil Lárus Johannsson, Erlingur |
author_sort |
Guðmundsdóttir, Sigríður Lára |
title |
Serum 25-hydroxyvitamin D concentrations in 16-year-old Icelandic adolescent and its association with bone mineral density |
title_short |
Serum 25-hydroxyvitamin D concentrations in 16-year-old Icelandic adolescent and its association with bone mineral density |
title_full |
Serum 25-hydroxyvitamin D concentrations in 16-year-old Icelandic adolescent and its association with bone mineral density |
title_fullStr |
Serum 25-hydroxyvitamin D concentrations in 16-year-old Icelandic adolescent and its association with bone mineral density |
title_full_unstemmed |
Serum 25-hydroxyvitamin D concentrations in 16-year-old Icelandic adolescent and its association with bone mineral density |
title_sort |
serum 25-hydroxyvitamin d concentrations in 16-year-old icelandic adolescent and its association with bone mineral density |
publishDate |
2020 |
url |
https://hdl.handle.net/11250/2676002 https://doi.org/10.1017/S1368980019004142 |
genre |
Iceland |
genre_facet |
Iceland |
op_source |
1329-1333 23 Public Health Nutrition 8 |
op_relation |
Gudmundsdottir, S. L., Hrafnkelsson, H., Sigurdsson, E. L., & Johannsson, E. (2020). Serum 25-hydroxyvitamin D concentrations in 16-year-old Icelandic adolescent and its association with bone mineral density. Public Health Nutrition, 23(8), 1329-1333. urn:issn:1368-9800 https://hdl.handle.net/11250/2676002 https://doi.org/10.1017/S1368980019004142 cristin:1820880 |
op_rights |
Navngivelse 4.0 Internasjonal http://creativecommons.org/licenses/by/4.0/deed.no © The Author(s) |
op_doi |
https://doi.org/10.1017/S1368980019004142 |
container_title |
Public Health Nutrition |
container_volume |
23 |
container_issue |
8 |
container_start_page |
1329 |
op_container_end_page |
1333 |
_version_ |
1792501381353963520 |