Toxoplasma gondii infection in Philippines Rattus spp. confirmed through bioassay in Mus musculus
The absence of any published work on T. gondii infection in rats in the Philippines has compelled us to embark on this present study. Toxoplasma gondii infection was serologically ascertained in 55.5% of Rattus norvegicus and Rattus rattus mindanensis caught in agricultural (AGR), commercial (COM) a...
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fthrcak:oai:hrcak.srce.hr:5144 2023-05-15T18:05:28+02:00 Toxoplasma gondii infection in Philippines Rattus spp. confirmed through bioassay in Mus musculus Cabanacan-Salibay, Cristina Claveria, Florencia Garcia 2006-08-20 pdf http://hrcak.srce.hr/5144 http://hrcak.srce.hr/file/8251 en eng Faculty of Veterinary Medicine University of Zagreb http://hrcak.srce.hr/5144 http://hrcak.srce.hr/file/8251 Full-text papers can be used for personal or educational purposes only. Authors' and publisher's copyrights must be acknowledged. Veterinary Archives (veterinarski.arhiv@vef.hr); Vol.76 No.4 Toxoplasma gondii Rattus spp. Philippines serology experimental mice text 2006 fthrcak 2012-10-27T08:56:25Z The absence of any published work on T. gondii infection in rats in the Philippines has compelled us to embark on this present study. Toxoplasma gondii infection was serologically ascertained in 55.5% of Rattus norvegicus and Rattus rattus mindanensis caught in agricultural (AGR), commercial (COM) and residential (RES) sites at Dasmariñas, Cavite. Infection accounted for 60.0% in R. norvegicus and 50.0% in R. rattus mindanensis, with anti-T. gondii antibodies (Abs) titre ranging from 1:64 to 1:2048. Chronic infection (≥1:256 anti- T. gondii Abs) was detected in 53 (61.0%) rats. There was an insignificant association between parasite infectivity, rat species and collection sites. In mice, seropositivity was 65.0% (93/144), and tissue cysts were detected only among those exposed to brain tissue of RES caught R. rattus mindanensis. Although mouse infection was clearly inoculum dose related, the consistent higher infectivity of T. gondii parasite from AGR and COM relative to RES caught Rattus spp. and other biological parameters, such as clinical manifestations, parasite encystations and mortality, suggest intraspecific strain differences in T. gondii infecting the Rattus spp. populations. We are currently assessing the severity of histopathology in seropositive mice exposed to brain tissue of chronically infected R. norvegicus and R. rattus mindanensis across the three collection sites, and we hope to provide additional information that would help clarify present findings and observations. The present study represents the first confirmed report of T. gondii infection of rats in the country. Text Rattus rattus Hrčak - Portal of scientific journals of Croatia |
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Toxoplasma gondii Rattus spp. Philippines serology experimental mice |
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Toxoplasma gondii Rattus spp. Philippines serology experimental mice Cabanacan-Salibay, Cristina Claveria, Florencia Garcia Toxoplasma gondii infection in Philippines Rattus spp. confirmed through bioassay in Mus musculus |
topic_facet |
Toxoplasma gondii Rattus spp. Philippines serology experimental mice |
description |
The absence of any published work on T. gondii infection in rats in the Philippines has compelled us to embark on this present study. Toxoplasma gondii infection was serologically ascertained in 55.5% of Rattus norvegicus and Rattus rattus mindanensis caught in agricultural (AGR), commercial (COM) and residential (RES) sites at Dasmariñas, Cavite. Infection accounted for 60.0% in R. norvegicus and 50.0% in R. rattus mindanensis, with anti-T. gondii antibodies (Abs) titre ranging from 1:64 to 1:2048. Chronic infection (≥1:256 anti- T. gondii Abs) was detected in 53 (61.0%) rats. There was an insignificant association between parasite infectivity, rat species and collection sites. In mice, seropositivity was 65.0% (93/144), and tissue cysts were detected only among those exposed to brain tissue of RES caught R. rattus mindanensis. Although mouse infection was clearly inoculum dose related, the consistent higher infectivity of T. gondii parasite from AGR and COM relative to RES caught Rattus spp. and other biological parameters, such as clinical manifestations, parasite encystations and mortality, suggest intraspecific strain differences in T. gondii infecting the Rattus spp. populations. We are currently assessing the severity of histopathology in seropositive mice exposed to brain tissue of chronically infected R. norvegicus and R. rattus mindanensis across the three collection sites, and we hope to provide additional information that would help clarify present findings and observations. The present study represents the first confirmed report of T. gondii infection of rats in the country. |
format |
Text |
author |
Cabanacan-Salibay, Cristina Claveria, Florencia Garcia |
author_facet |
Cabanacan-Salibay, Cristina Claveria, Florencia Garcia |
author_sort |
Cabanacan-Salibay, Cristina |
title |
Toxoplasma gondii infection in Philippines Rattus spp. confirmed through bioassay in Mus musculus |
title_short |
Toxoplasma gondii infection in Philippines Rattus spp. confirmed through bioassay in Mus musculus |
title_full |
Toxoplasma gondii infection in Philippines Rattus spp. confirmed through bioassay in Mus musculus |
title_fullStr |
Toxoplasma gondii infection in Philippines Rattus spp. confirmed through bioassay in Mus musculus |
title_full_unstemmed |
Toxoplasma gondii infection in Philippines Rattus spp. confirmed through bioassay in Mus musculus |
title_sort |
toxoplasma gondii infection in philippines rattus spp. confirmed through bioassay in mus musculus |
publisher |
Faculty of Veterinary Medicine University of Zagreb |
publishDate |
2006 |
url |
http://hrcak.srce.hr/5144 http://hrcak.srce.hr/file/8251 |
genre |
Rattus rattus |
genre_facet |
Rattus rattus |
op_source |
Veterinary Archives (veterinarski.arhiv@vef.hr); Vol.76 No.4 |
op_relation |
http://hrcak.srce.hr/5144 http://hrcak.srce.hr/file/8251 |
op_rights |
Full-text papers can be used for personal or educational purposes only. Authors' and publisher's copyrights must be acknowledged. |
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1766176944703930368 |