Mixed Anhydrides of Penicillinic and Cephalosporinic Acids with N-Acyl Carbamic Acid

Mixed anhydrides with penicillinic acids (III) were unstable and gave N-acyl, amides IV. Only III with butyrolactam was stable and reacted with alcohols to give esters V. All anhydrides with cephalosporinic acids (VIlI) yielded symmetric anhydrides IX. Alcoholysis of IX gave cephalosporinic ester X,...

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Main Authors: Kovačević, Miće, Herak, Jure J., Gašpert, Branimir
Format: Article in Journal/Newspaper
Language:English
Published: Croatian Chemical Society 1985
Subjects:
Carbonic acid
Online Access:http://hrcak.srce.hr/177771
http://hrcak.srce.hr/file/262003
id fthrcak:oai:hrcak.srce.hr:177771
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spelling fthrcak:oai:hrcak.srce.hr:177771 2023-05-15T15:52:29+02:00 Mixed Anhydrides of Penicillinic and Cephalosporinic Acids with N-Acyl Carbamic Acid Kovačević, Miće Herak, Jure J. Gašpert, Branimir 1985-10-31 application/pdf http://hrcak.srce.hr/177771 http://hrcak.srce.hr/file/262003 eng eng Croatian Chemical Society http://hrcak.srce.hr/177771 info:eu-repo/semantics/openAccess Croatica Chemica Acta is at the highest possible level of Open Access, meaning that all content is immediately and freely available to anyone, anywhere, to be downloaded, printed, distributed, read, reused, self archived, and re-mixed (including commercially) without restriction, as long as the author and the original source are properly at-tributed according to the Creative Commons Attribution 4.0 International License (CC BY). The author(s) hold the copyright and retain publishing rights without restrictions. CC BY (Creative Commons Attribution) is the most accommodating of public copyright licenses as defined by Creative Commons, a nonprofit organization that provides legal tools for sharing and use of creative works and research. The CC BY license is recommended for maximum dissemination and use of licensed materials. All content published in Croatica Chemica Acta is available under CC BY, meaning anyone is free to use and reuse the content provided the original source and authors are credited. The copyright is held and retained. The author(s) hold the copyright without restrictions. is the appropriate license for publicly funded research; it maximizes the potential for both economic and scholarly impact, protects the rights of authors and strengthens the long-standing tradition of appropriate attribution and credit for scholarship. CC-BY Croatica Chemica Acta ISSN 0011-1643 (Print) ISSN 1334-417X (Online) Volume 58 Issue 3 text info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion 1985 fthrcak 2017-03-22T23:50:53Z Mixed anhydrides with penicillinic acids (III) were unstable and gave N-acyl, amides IV. Only III with butyrolactam was stable and reacted with alcohols to give esters V. All anhydrides with cephalosporinic acids (VIlI) yielded symmetric anhydrides IX. Alcoholysis of IX gave cephalosporinic ester X, while aminolysis yielded amide. Formation of postulated isomeric mixed anhydride with O-imino carbonic acid ester XlIIb is discussed. Article in Journal/Newspaper Carbonic acid Hrčak - Portal of scientific journals of Croatia
institution Open Polar
collection Hrčak - Portal of scientific journals of Croatia
op_collection_id fthrcak
language English
description Mixed anhydrides with penicillinic acids (III) were unstable and gave N-acyl, amides IV. Only III with butyrolactam was stable and reacted with alcohols to give esters V. All anhydrides with cephalosporinic acids (VIlI) yielded symmetric anhydrides IX. Alcoholysis of IX gave cephalosporinic ester X, while aminolysis yielded amide. Formation of postulated isomeric mixed anhydride with O-imino carbonic acid ester XlIIb is discussed.
format Article in Journal/Newspaper
author Kovačević, Miće
Herak, Jure J.
Gašpert, Branimir
spellingShingle Kovačević, Miće
Herak, Jure J.
Gašpert, Branimir
Mixed Anhydrides of Penicillinic and Cephalosporinic Acids with N-Acyl Carbamic Acid
author_facet Kovačević, Miće
Herak, Jure J.
Gašpert, Branimir
author_sort Kovačević, Miće
title Mixed Anhydrides of Penicillinic and Cephalosporinic Acids with N-Acyl Carbamic Acid
title_short Mixed Anhydrides of Penicillinic and Cephalosporinic Acids with N-Acyl Carbamic Acid
title_full Mixed Anhydrides of Penicillinic and Cephalosporinic Acids with N-Acyl Carbamic Acid
title_fullStr Mixed Anhydrides of Penicillinic and Cephalosporinic Acids with N-Acyl Carbamic Acid
title_full_unstemmed Mixed Anhydrides of Penicillinic and Cephalosporinic Acids with N-Acyl Carbamic Acid
title_sort mixed anhydrides of penicillinic and cephalosporinic acids with n-acyl carbamic acid
publisher Croatian Chemical Society
publishDate 1985
url http://hrcak.srce.hr/177771
http://hrcak.srce.hr/file/262003
genre Carbonic acid
genre_facet Carbonic acid
op_source Croatica Chemica Acta
ISSN 0011-1643 (Print)
ISSN 1334-417X (Online)
Volume 58
Issue 3
op_relation http://hrcak.srce.hr/177771
op_rights info:eu-repo/semantics/openAccess
Croatica Chemica Acta is at the highest possible level of Open Access, meaning that all content is immediately and freely available to anyone, anywhere, to be downloaded, printed, distributed, read, reused, self archived, and re-mixed (including commercially) without restriction, as long as the author and the original source are properly at-tributed according to the Creative Commons Attribution 4.0 International License (CC BY). The author(s) hold the copyright and retain publishing rights without restrictions. CC BY (Creative Commons Attribution) is the most accommodating of public copyright licenses as defined by Creative Commons, a nonprofit organization that provides legal tools for sharing and use of creative works and research. The CC BY license is recommended for maximum dissemination and use of licensed materials. All content published in Croatica Chemica Acta is available under CC BY, meaning anyone is free to use and reuse the content provided the original source and authors are credited. The copyright is held and retained. The author(s) hold the copyright without restrictions. is the appropriate license for publicly funded research; it maximizes the potential for both economic and scholarly impact, protects the rights of authors and strengthens the long-standing tradition of appropriate attribution and credit for scholarship.
op_rightsnorm CC-BY
_version_ 1766387655710343168

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