Epidemiological studies of avian influenza

Recent outbreaks of highly pathogenic avian influenza (HPAI) have spread from southeast Asia to 62 Eurasian and African countries. H5N1 viruses isolated from dead water birds in Mongolia on the way back to their nesting areas in Siberia in April to May in 2005, 2006, 2008 and 2009 were genetically c...

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Main Author: Abdul Samad, Rozanah Asmah
Format: Other/Unknown Material
Language:English
Published: Hokkaido University
Subjects:
649
Online Access:http://hdl.handle.net/2115/44986
https://doi.org/10.14943/doctoral.k9958
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spelling fthokunivhus:oai:eprints.lib.hokudai.ac.jp:2115/44986 2023-05-15T18:44:13+02:00 Epidemiological studies of avian influenza 鳥インフルエンザの疫学的研究 Abdul Samad, Rozanah Asmah 51p. http://hdl.handle.net/2115/44986 https://doi.org/10.14943/doctoral.k9958 eng eng Hokkaido University http://hdl.handle.net/2115/44986 doi:10.14943/doctoral.k9958 北海道大学. 博士(獣医学) 649 theses (doctoral) fthokunivhus https://doi.org/10.14943/doctoral.k9958 2022-11-18T01:02:07Z Recent outbreaks of highly pathogenic avian influenza (HPAI) have spread from southeast Asia to 62 Eurasian and African countries. H5N1 viruses isolated from dead water birds in Mongolia on the way back to their nesting areas in Siberia in April to May in 2005, 2006, 2008 and 2009 were genetically closely related to those isolated from birds in China, and some southeast Asian countries. It is now a serious concern that these HPAI viruses may perpetuate in the lakes where migratory water birds nest in summer.Therefore, virological surveillance of avian influenza virus in the migratory birds that fly from their nesting lakes in Siberia to Hokkaido, Japan was carried out in autumn every year. During 2008-2009, 62 influenza viruses of 21 different combinations of hemagglutinin (HA) and neuraminidase (NA) subtypes were isolated. Up to September 2010, no HPAI virus has been found, indicating that H5N1 HPAI virus has not perpetuated at least dominantly in the lakes where ducks nest in summer in Siberia. It is reported that the PB2 protein is a component of the viral polymerase complex that plays an important role in virus replication, and is a determinant of host range and pathogenicity of influenza viruses. The PB2 genes of 57 influenza viruses out of 283 influenza viruses isolated in Hokkaido in 2000-2009 were phylogenetically analysed. None of the genes showed close relation to those of H5N1 HPAI viruses that were detected in wild birds found dead in Eurasia on the way back to their northern territory in spring.Avian influenza virus strains isolated from migratory ducks in the global surveillance have been stored for the use for vaccines and diagnosis. Vaccine is used to reduce virus shedding into the environment and as an optional measure in cases where the disease spreads widely, in addition to stamping out. In the present study, the efficacy of the vaccine was comparable to that prepared from genetically modified HPAI virus strain ΔRRRRK rg-A/whooper swan/Mongolia/3/2005 (H5N1), which is more antigenically ... Other/Unknown Material Whooper Swan Siberia Hokkaido University Collection of Scholarly and Academic Papers (HUSCAP)
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collection Hokkaido University Collection of Scholarly and Academic Papers (HUSCAP)
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language English
topic 649
spellingShingle 649
Abdul Samad, Rozanah Asmah
Epidemiological studies of avian influenza
topic_facet 649
description Recent outbreaks of highly pathogenic avian influenza (HPAI) have spread from southeast Asia to 62 Eurasian and African countries. H5N1 viruses isolated from dead water birds in Mongolia on the way back to their nesting areas in Siberia in April to May in 2005, 2006, 2008 and 2009 were genetically closely related to those isolated from birds in China, and some southeast Asian countries. It is now a serious concern that these HPAI viruses may perpetuate in the lakes where migratory water birds nest in summer.Therefore, virological surveillance of avian influenza virus in the migratory birds that fly from their nesting lakes in Siberia to Hokkaido, Japan was carried out in autumn every year. During 2008-2009, 62 influenza viruses of 21 different combinations of hemagglutinin (HA) and neuraminidase (NA) subtypes were isolated. Up to September 2010, no HPAI virus has been found, indicating that H5N1 HPAI virus has not perpetuated at least dominantly in the lakes where ducks nest in summer in Siberia. It is reported that the PB2 protein is a component of the viral polymerase complex that plays an important role in virus replication, and is a determinant of host range and pathogenicity of influenza viruses. The PB2 genes of 57 influenza viruses out of 283 influenza viruses isolated in Hokkaido in 2000-2009 were phylogenetically analysed. None of the genes showed close relation to those of H5N1 HPAI viruses that were detected in wild birds found dead in Eurasia on the way back to their northern territory in spring.Avian influenza virus strains isolated from migratory ducks in the global surveillance have been stored for the use for vaccines and diagnosis. Vaccine is used to reduce virus shedding into the environment and as an optional measure in cases where the disease spreads widely, in addition to stamping out. In the present study, the efficacy of the vaccine was comparable to that prepared from genetically modified HPAI virus strain ΔRRRRK rg-A/whooper swan/Mongolia/3/2005 (H5N1), which is more antigenically ...
format Other/Unknown Material
author Abdul Samad, Rozanah Asmah
author_facet Abdul Samad, Rozanah Asmah
author_sort Abdul Samad, Rozanah Asmah
title Epidemiological studies of avian influenza
title_short Epidemiological studies of avian influenza
title_full Epidemiological studies of avian influenza
title_fullStr Epidemiological studies of avian influenza
title_full_unstemmed Epidemiological studies of avian influenza
title_sort epidemiological studies of avian influenza
publisher Hokkaido University
url http://hdl.handle.net/2115/44986
https://doi.org/10.14943/doctoral.k9958
genre Whooper Swan
Siberia
genre_facet Whooper Swan
Siberia
op_relation http://hdl.handle.net/2115/44986
doi:10.14943/doctoral.k9958
北海道大学. 博士(獣医学)
op_doi https://doi.org/10.14943/doctoral.k9958
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