Effects of Age and Sex on Estimated Diabetes Prevalence Using Different Diagnostic Criteria: The Tromsø OGTT Study
HbA1c 6.5% has recently been recommended as an alternative diagnostic criterion for diabetes. The aims of the study were to evaluate the effects of age, sex, and other factors on prevalence of diabetes and to compare risk profiles of subjects with diabetes when defined by HbA1c and glucose criteria....
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fthindawi:oai:hindawi.com:10.1155/2013/613475 2023-05-15T18:34:23+02:00 Effects of Age and Sex on Estimated Diabetes Prevalence Using Different Diagnostic Criteria: The Tromsø OGTT Study Moira Strand Hutchinson Ragnar Martin Joakimsen Inger Njølstad Henrik Schirmer Yngve Figenschau Johan Svartberg Rolf Jorde 2013 https://doi.org/10.1155/2013/613475 en eng International Journal of Endocrinology https://doi.org/10.1155/2013/613475 Copyright © 2013 Moira Strand Hutchinson et al. Research Article 2013 fthindawi https://doi.org/10.1155/2013/613475 2019-05-26T02:08:47Z HbA1c 6.5% has recently been recommended as an alternative diagnostic criterion for diabetes. The aims of the study were to evaluate the effects of age, sex, and other factors on prevalence of diabetes and to compare risk profiles of subjects with diabetes when defined by HbA1c and glucose criteria. Subjects were recruited among participants in the longitudinal population-based Tromsø Study. HbA1c, fasting plasma glucose, and 2-hour plasma glucose were measured in 3,476 subjects. In total, 294 subjects met one or more of the diagnostic criteria for diabetes; 95 met the HbA1c criterion only, 130 met the glucose criteria only, and 69 met both. Among subjects with diabetes detected by glucose criteria (regardless of HbA1c), isolated raised 2-hour plasma glucose was more common in subjects aged ≥ 60 years as compared to younger subjects and in elderly women as compared to elderly men. Subjects with diabetes detected by glucose criteria only had worse cardiometabolic risk profiles than those detected by HbA1c only. In conclusion, the current HbA1c and glucose criteria defined different subjects with diabetes with only modest overlap. Among a substantial proportion of elderly subjects, and especially elderly women, the 2-hour plasma glucose was the only abnormal value. Article in Journal/Newspaper Tromsø Hindawi Publishing Corporation Tromsø International Journal of Endocrinology 2013 1 9 |
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Hindawi Publishing Corporation |
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HbA1c 6.5% has recently been recommended as an alternative diagnostic criterion for diabetes. The aims of the study were to evaluate the effects of age, sex, and other factors on prevalence of diabetes and to compare risk profiles of subjects with diabetes when defined by HbA1c and glucose criteria. Subjects were recruited among participants in the longitudinal population-based Tromsø Study. HbA1c, fasting plasma glucose, and 2-hour plasma glucose were measured in 3,476 subjects. In total, 294 subjects met one or more of the diagnostic criteria for diabetes; 95 met the HbA1c criterion only, 130 met the glucose criteria only, and 69 met both. Among subjects with diabetes detected by glucose criteria (regardless of HbA1c), isolated raised 2-hour plasma glucose was more common in subjects aged ≥ 60 years as compared to younger subjects and in elderly women as compared to elderly men. Subjects with diabetes detected by glucose criteria only had worse cardiometabolic risk profiles than those detected by HbA1c only. In conclusion, the current HbA1c and glucose criteria defined different subjects with diabetes with only modest overlap. Among a substantial proportion of elderly subjects, and especially elderly women, the 2-hour plasma glucose was the only abnormal value. |
format |
Article in Journal/Newspaper |
author |
Moira Strand Hutchinson Ragnar Martin Joakimsen Inger Njølstad Henrik Schirmer Yngve Figenschau Johan Svartberg Rolf Jorde |
spellingShingle |
Moira Strand Hutchinson Ragnar Martin Joakimsen Inger Njølstad Henrik Schirmer Yngve Figenschau Johan Svartberg Rolf Jorde Effects of Age and Sex on Estimated Diabetes Prevalence Using Different Diagnostic Criteria: The Tromsø OGTT Study |
author_facet |
Moira Strand Hutchinson Ragnar Martin Joakimsen Inger Njølstad Henrik Schirmer Yngve Figenschau Johan Svartberg Rolf Jorde |
author_sort |
Moira Strand Hutchinson |
title |
Effects of Age and Sex on Estimated Diabetes Prevalence Using Different Diagnostic Criteria: The Tromsø OGTT Study |
title_short |
Effects of Age and Sex on Estimated Diabetes Prevalence Using Different Diagnostic Criteria: The Tromsø OGTT Study |
title_full |
Effects of Age and Sex on Estimated Diabetes Prevalence Using Different Diagnostic Criteria: The Tromsø OGTT Study |
title_fullStr |
Effects of Age and Sex on Estimated Diabetes Prevalence Using Different Diagnostic Criteria: The Tromsø OGTT Study |
title_full_unstemmed |
Effects of Age and Sex on Estimated Diabetes Prevalence Using Different Diagnostic Criteria: The Tromsø OGTT Study |
title_sort |
effects of age and sex on estimated diabetes prevalence using different diagnostic criteria: the tromsø ogtt study |
publisher |
International Journal of Endocrinology |
publishDate |
2013 |
url |
https://doi.org/10.1155/2013/613475 |
geographic |
Tromsø |
geographic_facet |
Tromsø |
genre |
Tromsø |
genre_facet |
Tromsø |
op_relation |
https://doi.org/10.1155/2013/613475 |
op_rights |
Copyright © 2013 Moira Strand Hutchinson et al. |
op_doi |
https://doi.org/10.1155/2013/613475 |
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International Journal of Endocrinology |
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2013 |
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1 |
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9 |
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1766219112959180800 |