Tuberculous Lymphadenitis in Manitoba: Incidence, Clinical Characteristics and Treatment
BACKGROUND: Tuberculous lymphadenitis (TBL) is an important form of extrapulmonary tuberculosis (TB). Recent studies have shown an increase in TBL in Canada.OBJECTIVES: To determine the incidence of TBL in Manitoba and to identify the characteristics associated with its presentation, diagnosis and t...
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fthindawi:oai:hindawi.com:10.1155/2004/826501 2023-05-15T16:16:52+02:00 Tuberculous Lymphadenitis in Manitoba: Incidence, Clinical Characteristics and Treatment Victoria J Cook Jure Manfreda Earl S Hershfield 2004 https://doi.org/10.1155/2004/826501 en eng Canadian Respiratory Journal https://doi.org/10.1155/2004/826501 Copyright © 2004 Hindawi Publishing Corporation. Original Article 2004 fthindawi https://doi.org/10.1155/2004/826501 2019-05-26T06:22:58Z BACKGROUND: Tuberculous lymphadenitis (TBL) is an important form of extrapulmonary tuberculosis (TB). Recent studies have shown an increase in TBL in Canada.OBJECTIVES: To determine the incidence of TBL in Manitoba and to identify the characteristics associated with its presentation, diagnosis and treatment.METHODS: Population data from the Manitoba Health Population Registry, the First Nations and Inuit Health Branch of Health Canada, and Statistics Canada were used to calculate incidence. Case characteristics and outcomes were determined by a systematic, retrospective review of all cases between January 1, 1990 and December 31, 2000.RESULTS: One-hundred forty seven cases of TBL were identified during the study period; 77% confirmed by culture; 68% women. TBL was found in Canadian-born/nonstatus Aboriginal (12%), status Aboriginal (29%) and foreign-born (59%) populations. Incidence of TBL was 1.17 per 100,000 person years (95% CI 0.98 to 1.36). The highest incidence was in status Aboriginals over 65 years (16.85 per 100,000 person years; 95% CI 3.37 to 30.33). TBL is seen most often in Western Pacific women. The most common presentation was a single, enlarged cervical node (80%). No atypical mycobacterium was found. Drug resistance occurred in 13% of cases and only in the foreign-born. Cure rates (81%) were influenced by comorbidity and burden of TB disease. Relapse occurred in 8.1 per 1000 person years of follow-up (95% CI 1.7 to 23.7).CONCLUSIONS: Respiratory physicians, who manage the majority of TB disease in Canada, need to remain aware that TB is an important and treatable cause of enlarged lymph nodes. Article in Journal/Newspaper First Nations inuit Hindawi Publishing Corporation Canada Pacific Canadian Respiratory Journal 11 4 279 286 |
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BACKGROUND: Tuberculous lymphadenitis (TBL) is an important form of extrapulmonary tuberculosis (TB). Recent studies have shown an increase in TBL in Canada.OBJECTIVES: To determine the incidence of TBL in Manitoba and to identify the characteristics associated with its presentation, diagnosis and treatment.METHODS: Population data from the Manitoba Health Population Registry, the First Nations and Inuit Health Branch of Health Canada, and Statistics Canada were used to calculate incidence. Case characteristics and outcomes were determined by a systematic, retrospective review of all cases between January 1, 1990 and December 31, 2000.RESULTS: One-hundred forty seven cases of TBL were identified during the study period; 77% confirmed by culture; 68% women. TBL was found in Canadian-born/nonstatus Aboriginal (12%), status Aboriginal (29%) and foreign-born (59%) populations. Incidence of TBL was 1.17 per 100,000 person years (95% CI 0.98 to 1.36). The highest incidence was in status Aboriginals over 65 years (16.85 per 100,000 person years; 95% CI 3.37 to 30.33). TBL is seen most often in Western Pacific women. The most common presentation was a single, enlarged cervical node (80%). No atypical mycobacterium was found. Drug resistance occurred in 13% of cases and only in the foreign-born. Cure rates (81%) were influenced by comorbidity and burden of TB disease. Relapse occurred in 8.1 per 1000 person years of follow-up (95% CI 1.7 to 23.7).CONCLUSIONS: Respiratory physicians, who manage the majority of TB disease in Canada, need to remain aware that TB is an important and treatable cause of enlarged lymph nodes. |
format |
Article in Journal/Newspaper |
author |
Victoria J Cook Jure Manfreda Earl S Hershfield |
spellingShingle |
Victoria J Cook Jure Manfreda Earl S Hershfield Tuberculous Lymphadenitis in Manitoba: Incidence, Clinical Characteristics and Treatment |
author_facet |
Victoria J Cook Jure Manfreda Earl S Hershfield |
author_sort |
Victoria J Cook |
title |
Tuberculous Lymphadenitis in Manitoba: Incidence, Clinical Characteristics and Treatment |
title_short |
Tuberculous Lymphadenitis in Manitoba: Incidence, Clinical Characteristics and Treatment |
title_full |
Tuberculous Lymphadenitis in Manitoba: Incidence, Clinical Characteristics and Treatment |
title_fullStr |
Tuberculous Lymphadenitis in Manitoba: Incidence, Clinical Characteristics and Treatment |
title_full_unstemmed |
Tuberculous Lymphadenitis in Manitoba: Incidence, Clinical Characteristics and Treatment |
title_sort |
tuberculous lymphadenitis in manitoba: incidence, clinical characteristics and treatment |
publisher |
Canadian Respiratory Journal |
publishDate |
2004 |
url |
https://doi.org/10.1155/2004/826501 |
geographic |
Canada Pacific |
geographic_facet |
Canada Pacific |
genre |
First Nations inuit |
genre_facet |
First Nations inuit |
op_relation |
https://doi.org/10.1155/2004/826501 |
op_rights |
Copyright © 2004 Hindawi Publishing Corporation. |
op_doi |
https://doi.org/10.1155/2004/826501 |
container_title |
Canadian Respiratory Journal |
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11 |
container_issue |
4 |
container_start_page |
279 |
op_container_end_page |
286 |
_version_ |
1766002718819745792 |