The Effects of Heart and Skeletal Muscle Inflammation and Cardiomyopathy Syndrome on Creatine Kinase and Lactate Dehydrogenase Levels in Atlantic Salmon (Salmo salar L.)
Heart and skeletal muscle inflammation (HSMI) and cardiomyopathy syndrome (CMS) are putative viral cardiac diseases of Atlantic salmon. This study examined the levels and correlated the serum enzymes creatine kinase (CK) and lactate dehydrogenase (LDH) to the histopathology of clinical outbreaks of...
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fthindawi:oai:hindawi.com:10.1100/2012/741302 2023-05-15T15:30:11+02:00 The Effects of Heart and Skeletal Muscle Inflammation and Cardiomyopathy Syndrome on Creatine Kinase and Lactate Dehydrogenase Levels in Atlantic Salmon (Salmo salar L.) Muhammad Naveed Yousaf Mark D. Powell 2012 https://doi.org/10.1100/2012/741302 en eng The Scientific World Journal https://doi.org/10.1100/2012/741302 Copyright © 2012 Muhammad Naveed Yousaf and Mark D. Powell. Pathology Research Article 2012 fthindawi https://doi.org/10.1100/2012/741302 2019-05-26T01:41:20Z Heart and skeletal muscle inflammation (HSMI) and cardiomyopathy syndrome (CMS) are putative viral cardiac diseases of Atlantic salmon. This study examined the levels and correlated the serum enzymes creatine kinase (CK) and lactate dehydrogenase (LDH) to the histopathology of clinical outbreaks of HSMI and chronic CMS in farmed Atlantic salmon. A total of 75 fish from 3 different HSMI outbreaks, 30 chronic CMS fish, and 68 fish from 3 nondiseased fish groups were used as the study population (N=173). Serum CK and LDH levels correlated significantly with the total inflammation and total necrosis scores for HSMI fish (P=0.001). However, no correlation was identified for enzyme levels and histopathology scores for chronic CMS fish. The significantly increased CK and LDH levels and their positive correlations to histopathology differentiate HSMI from CMS clinically suggesting the potential use of enzymes for screening for HSMI is promising. Article in Journal/Newspaper Atlantic salmon Salmo salar Hindawi Publishing Corporation The Scientific World Journal 2012 1 9 |
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Hindawi Publishing Corporation |
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English |
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Pathology |
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Pathology Muhammad Naveed Yousaf Mark D. Powell The Effects of Heart and Skeletal Muscle Inflammation and Cardiomyopathy Syndrome on Creatine Kinase and Lactate Dehydrogenase Levels in Atlantic Salmon (Salmo salar L.) |
topic_facet |
Pathology |
description |
Heart and skeletal muscle inflammation (HSMI) and cardiomyopathy syndrome (CMS) are putative viral cardiac diseases of Atlantic salmon. This study examined the levels and correlated the serum enzymes creatine kinase (CK) and lactate dehydrogenase (LDH) to the histopathology of clinical outbreaks of HSMI and chronic CMS in farmed Atlantic salmon. A total of 75 fish from 3 different HSMI outbreaks, 30 chronic CMS fish, and 68 fish from 3 nondiseased fish groups were used as the study population (N=173). Serum CK and LDH levels correlated significantly with the total inflammation and total necrosis scores for HSMI fish (P=0.001). However, no correlation was identified for enzyme levels and histopathology scores for chronic CMS fish. The significantly increased CK and LDH levels and their positive correlations to histopathology differentiate HSMI from CMS clinically suggesting the potential use of enzymes for screening for HSMI is promising. |
format |
Article in Journal/Newspaper |
author |
Muhammad Naveed Yousaf Mark D. Powell |
author_facet |
Muhammad Naveed Yousaf Mark D. Powell |
author_sort |
Muhammad Naveed Yousaf |
title |
The Effects of Heart and Skeletal Muscle Inflammation and Cardiomyopathy Syndrome on Creatine Kinase and Lactate Dehydrogenase Levels in Atlantic Salmon (Salmo salar L.) |
title_short |
The Effects of Heart and Skeletal Muscle Inflammation and Cardiomyopathy Syndrome on Creatine Kinase and Lactate Dehydrogenase Levels in Atlantic Salmon (Salmo salar L.) |
title_full |
The Effects of Heart and Skeletal Muscle Inflammation and Cardiomyopathy Syndrome on Creatine Kinase and Lactate Dehydrogenase Levels in Atlantic Salmon (Salmo salar L.) |
title_fullStr |
The Effects of Heart and Skeletal Muscle Inflammation and Cardiomyopathy Syndrome on Creatine Kinase and Lactate Dehydrogenase Levels in Atlantic Salmon (Salmo salar L.) |
title_full_unstemmed |
The Effects of Heart and Skeletal Muscle Inflammation and Cardiomyopathy Syndrome on Creatine Kinase and Lactate Dehydrogenase Levels in Atlantic Salmon (Salmo salar L.) |
title_sort |
effects of heart and skeletal muscle inflammation and cardiomyopathy syndrome on creatine kinase and lactate dehydrogenase levels in atlantic salmon (salmo salar l.) |
publisher |
The Scientific World Journal |
publishDate |
2012 |
url |
https://doi.org/10.1100/2012/741302 |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_relation |
https://doi.org/10.1100/2012/741302 |
op_rights |
Copyright © 2012 Muhammad Naveed Yousaf and Mark D. Powell. |
op_doi |
https://doi.org/10.1100/2012/741302 |
container_title |
The Scientific World Journal |
container_volume |
2012 |
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1 |
op_container_end_page |
9 |
_version_ |
1766360625269702656 |