Leishmaniasis in tuscany (Italy): VII. Studies on the role of the black rat, Rattus rattus, in the epidemiology of visceral leishmaniasis
The recent finding that four Leishmania isolates from Rattus rattus are enzymologically identical to L. infantum , aetiological agent of human and canine visceral leishmaniasis in the Mediterranean area, has stimulated further research on the role of R. rattus in the epidemiology of visceral leishma...
Published in: | Transactions of the Royal Society of Tropical Medicine and Hygiene |
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Oxford University Press
1983
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fthighwire:oai:open-archive.highwire.org:trstmh:77/4/427 2023-05-15T18:04:56+02:00 Leishmaniasis in tuscany (Italy): VII. Studies on the role of the black rat, Rattus rattus, in the epidemiology of visceral leishmaniasis Gradoni, L. Pozio, E. Gramiccia, M. Maroli, M. Bettini, S. 1983-01-01 00:00:00.0 text/html http://trstmh.oxfordjournals.org/cgi/content/short/77/4/427 https://doi.org/10.1016/0035-9203(83)90102-5 en eng Oxford University Press http://trstmh.oxfordjournals.org/cgi/content/short/77/4/427 http://dx.doi.org/10.1016/0035-9203(83)90102-5 Copyright (C) 1983, Royal Society of Tropical Medicine and Hygiene Articles TEXT 1983 fthighwire https://doi.org/10.1016/0035-9203(83)90102-5 2013-05-27T10:59:54Z The recent finding that four Leishmania isolates from Rattus rattus are enzymologically identical to L. infantum , aetiological agent of human and canine visceral leishmaniasis in the Mediterranean area, has stimulated further research on the role of R. rattus in the epidemiology of visceral leishmaniasis in Tuscany, Italy. The present work has led to the following results: (a) R. rattus experimentally infected with L. infantum displayed a general resistance to the parasite, even though it appeared that a very low number of amastigotes persisted in the animal for a long period; (b) Phlebotomus perniciosus and P. perfiliewi induced to feed on rats, with either a massive visceral infection or a subpatent immunodepressed infection, became infected, though in different proportions; (c) P. perniciosus and P. perfiliewi were readily attracted to, and fed on, the black rat in nature. These findings, together with those obtained earlier, strongly suggest that the black rat may be one of the wild reservoirs of L. infantum in the areas under study. Text Rattus rattus HighWire Press (Stanford University) Transactions of the Royal Society of Tropical Medicine and Hygiene 77 4 427 431 |
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Articles Gradoni, L. Pozio, E. Gramiccia, M. Maroli, M. Bettini, S. Leishmaniasis in tuscany (Italy): VII. Studies on the role of the black rat, Rattus rattus, in the epidemiology of visceral leishmaniasis |
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Articles |
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The recent finding that four Leishmania isolates from Rattus rattus are enzymologically identical to L. infantum , aetiological agent of human and canine visceral leishmaniasis in the Mediterranean area, has stimulated further research on the role of R. rattus in the epidemiology of visceral leishmaniasis in Tuscany, Italy. The present work has led to the following results: (a) R. rattus experimentally infected with L. infantum displayed a general resistance to the parasite, even though it appeared that a very low number of amastigotes persisted in the animal for a long period; (b) Phlebotomus perniciosus and P. perfiliewi induced to feed on rats, with either a massive visceral infection or a subpatent immunodepressed infection, became infected, though in different proportions; (c) P. perniciosus and P. perfiliewi were readily attracted to, and fed on, the black rat in nature. These findings, together with those obtained earlier, strongly suggest that the black rat may be one of the wild reservoirs of L. infantum in the areas under study. |
format |
Text |
author |
Gradoni, L. Pozio, E. Gramiccia, M. Maroli, M. Bettini, S. |
author_facet |
Gradoni, L. Pozio, E. Gramiccia, M. Maroli, M. Bettini, S. |
author_sort |
Gradoni, L. |
title |
Leishmaniasis in tuscany (Italy): VII. Studies on the role of the black rat, Rattus rattus, in the epidemiology of visceral leishmaniasis |
title_short |
Leishmaniasis in tuscany (Italy): VII. Studies on the role of the black rat, Rattus rattus, in the epidemiology of visceral leishmaniasis |
title_full |
Leishmaniasis in tuscany (Italy): VII. Studies on the role of the black rat, Rattus rattus, in the epidemiology of visceral leishmaniasis |
title_fullStr |
Leishmaniasis in tuscany (Italy): VII. Studies on the role of the black rat, Rattus rattus, in the epidemiology of visceral leishmaniasis |
title_full_unstemmed |
Leishmaniasis in tuscany (Italy): VII. Studies on the role of the black rat, Rattus rattus, in the epidemiology of visceral leishmaniasis |
title_sort |
leishmaniasis in tuscany (italy): vii. studies on the role of the black rat, rattus rattus, in the epidemiology of visceral leishmaniasis |
publisher |
Oxford University Press |
publishDate |
1983 |
url |
http://trstmh.oxfordjournals.org/cgi/content/short/77/4/427 https://doi.org/10.1016/0035-9203(83)90102-5 |
genre |
Rattus rattus |
genre_facet |
Rattus rattus |
op_relation |
http://trstmh.oxfordjournals.org/cgi/content/short/77/4/427 http://dx.doi.org/10.1016/0035-9203(83)90102-5 |
op_rights |
Copyright (C) 1983, Royal Society of Tropical Medicine and Hygiene |
op_doi |
https://doi.org/10.1016/0035-9203(83)90102-5 |
container_title |
Transactions of the Royal Society of Tropical Medicine and Hygiene |
container_volume |
77 |
container_issue |
4 |
container_start_page |
427 |
op_container_end_page |
431 |
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1766176352221790208 |