Rats of the Genus Rattus are Reservoir Hosts for Pathogenic Bartonella Species: An Old World Origin for a New World Disease?
Bartonella species were isolated from the blood of 63 of 325 Rattus norvegicus and 11 of 92 Rattus rattus from 13 sites in the United States and Portugal. Infection in both Rattus species ranged from 0% (e.g., 0/87) to ∼60% (e.g., 35/62). A 337-bp fragment of the citrate synthase ( glt A) gene ampli...
Published in: | The Journal of Infectious Diseases |
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Oxford University Press
1999
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fthighwire:oai:open-archive.highwire.org:jinfdis:180/1/220 2023-05-15T18:05:14+02:00 Rats of the Genus Rattus are Reservoir Hosts for Pathogenic Bartonella Species: An Old World Origin for a New World Disease? Ellis, B. A. Regnery, R. L. Beati, L. Bacellar, F. Rood, M. Glass, G. G. Marston, E. Ksiazek, T. G. Jones, D. Childs, J. E. 1999-07-01 00:00:00.0 text/html http://jid.oxfordjournals.org/cgi/content/short/180/1/220 https://doi.org/10.1086/314824 en eng Oxford University Press http://jid.oxfordjournals.org/cgi/content/short/180/1/220 http://dx.doi.org/10.1086/314824 Copyright (C) 1999, Infectious Diseases Society of America Concise Communications TEXT 1999 fthighwire https://doi.org/10.1086/314824 2013-05-27T02:00:19Z Bartonella species were isolated from the blood of 63 of 325 Rattus norvegicus and 11 of 92 Rattus rattus from 13 sites in the United States and Portugal. Infection in both Rattus species ranged from 0% (e.g., 0/87) to ∼60% (e.g., 35/62). A 337-bp fragment of the citrate synthase ( glt A) gene amplified by polymerase chain reaction was sequenced from all 74 isolates. Isolates from R. norvegicus were most similar to Bartonella elizabethae , isolated previously from a patient with endocarditis (93%–100% sequence similarity), followed by Bartonella grahamii and other Bartonella species isolated from Old World rodents ( Clethrionomys species, Mus musculus , and Rattus species). These data suggest that Rattus species are a reservoir host for pathogenic Bartonella species and are consistent with a hypothesized Old World origin for Bartonella species recovered from Rattus species introduced into the Americas. Text Rattus rattus HighWire Press (Stanford University) The Journal of Infectious Diseases 180 1 220 224 |
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HighWire Press (Stanford University) |
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English |
topic |
Concise Communications |
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Concise Communications Ellis, B. A. Regnery, R. L. Beati, L. Bacellar, F. Rood, M. Glass, G. G. Marston, E. Ksiazek, T. G. Jones, D. Childs, J. E. Rats of the Genus Rattus are Reservoir Hosts for Pathogenic Bartonella Species: An Old World Origin for a New World Disease? |
topic_facet |
Concise Communications |
description |
Bartonella species were isolated from the blood of 63 of 325 Rattus norvegicus and 11 of 92 Rattus rattus from 13 sites in the United States and Portugal. Infection in both Rattus species ranged from 0% (e.g., 0/87) to ∼60% (e.g., 35/62). A 337-bp fragment of the citrate synthase ( glt A) gene amplified by polymerase chain reaction was sequenced from all 74 isolates. Isolates from R. norvegicus were most similar to Bartonella elizabethae , isolated previously from a patient with endocarditis (93%–100% sequence similarity), followed by Bartonella grahamii and other Bartonella species isolated from Old World rodents ( Clethrionomys species, Mus musculus , and Rattus species). These data suggest that Rattus species are a reservoir host for pathogenic Bartonella species and are consistent with a hypothesized Old World origin for Bartonella species recovered from Rattus species introduced into the Americas. |
format |
Text |
author |
Ellis, B. A. Regnery, R. L. Beati, L. Bacellar, F. Rood, M. Glass, G. G. Marston, E. Ksiazek, T. G. Jones, D. Childs, J. E. |
author_facet |
Ellis, B. A. Regnery, R. L. Beati, L. Bacellar, F. Rood, M. Glass, G. G. Marston, E. Ksiazek, T. G. Jones, D. Childs, J. E. |
author_sort |
Ellis, B. A. |
title |
Rats of the Genus Rattus are Reservoir Hosts for Pathogenic Bartonella Species: An Old World Origin for a New World Disease? |
title_short |
Rats of the Genus Rattus are Reservoir Hosts for Pathogenic Bartonella Species: An Old World Origin for a New World Disease? |
title_full |
Rats of the Genus Rattus are Reservoir Hosts for Pathogenic Bartonella Species: An Old World Origin for a New World Disease? |
title_fullStr |
Rats of the Genus Rattus are Reservoir Hosts for Pathogenic Bartonella Species: An Old World Origin for a New World Disease? |
title_full_unstemmed |
Rats of the Genus Rattus are Reservoir Hosts for Pathogenic Bartonella Species: An Old World Origin for a New World Disease? |
title_sort |
rats of the genus rattus are reservoir hosts for pathogenic bartonella species: an old world origin for a new world disease? |
publisher |
Oxford University Press |
publishDate |
1999 |
url |
http://jid.oxfordjournals.org/cgi/content/short/180/1/220 https://doi.org/10.1086/314824 |
genre |
Rattus rattus |
genre_facet |
Rattus rattus |
op_relation |
http://jid.oxfordjournals.org/cgi/content/short/180/1/220 http://dx.doi.org/10.1086/314824 |
op_rights |
Copyright (C) 1999, Infectious Diseases Society of America |
op_doi |
https://doi.org/10.1086/314824 |
container_title |
The Journal of Infectious Diseases |
container_volume |
180 |
container_issue |
1 |
container_start_page |
220 |
op_container_end_page |
224 |
_version_ |
1766176693113847808 |