No oxygen? No problem! Intrinsic brain tolerance to hypoxia in vertebrates

• Published in: Journal of Experimental Biology
• Main Authors: Larson, John, Drew, Kelly L., Folkow, Lars P., Milton, Sarah L., Park, Thomas J.
• Format: Text
• Language: English
• Published: Company of Biologists 2014
• Subjects: REVIEW; Arctic; Burrows
• Online Access: http://jeb.biologists.org/cgi/content/short/217/7/1024; https://doi.org/10.1242/jeb.085381

Many vertebrates are challenged by either chronic or acute episodes of low oxygen availability in their natural environments. Brain function is especially vulnerable to the effects of hypoxia and can be irreversibly impaired by even brief periods of low oxygen supply. This review describes recent re...