Variation in the innate and acquired arms of the immune system among five shorebird species
To contribute to an understanding of the evolutionary processes that shape variation in immune responses, we compared several components of the innate and acquired arms of the immune system in five related, but ecologically diverse, migratory shorebirds (ruff Philomachus pugnax L., ruddy turnstone A...
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fthighwire:oai:open-archive.highwire.org:jexbio:209/2/284 2023-05-15T15:23:18+02:00 Variation in the innate and acquired arms of the immune system among five shorebird species Mendes, Luisa Piersma, Theunis Hasselquist, Dennis Matson, Kevin D. Ricklefs, Robert E. 2006-01-15 00:00:00.0 text/html http://jeb.biologists.org/cgi/content/short/209/2/284 https://doi.org/10.1242/jeb.02015 en eng Company of Biologists http://jeb.biologists.org/cgi/content/short/209/2/284 http://dx.doi.org/10.1242/jeb.02015 Copyright (C) 2006, Company of Biologists Research Article TEXT 2006 fthighwire https://doi.org/10.1242/jeb.02015 2015-02-28T19:03:43Z To contribute to an understanding of the evolutionary processes that shape variation in immune responses, we compared several components of the innate and acquired arms of the immune system in five related, but ecologically diverse, migratory shorebirds (ruff Philomachus pugnax L., ruddy turnstone Arenaria interpres L., bar-tailed godwit Limosa lapponica L., sanderling Calidris alba Pallas and red knot C. canutus L.). We used a hemolysis-hemagglutination assay in free-living shorebirds to assess two of the innate components (natural antibodies and complement-mediated lysis), and a modified quantitative enzyme-linked immunosorbent assay in birds held in captivity to assess the acquired component (humoral antibodies against tetanus and diphtheria toxoid) of immunity. Ruddy turnstones showed the highest levels of both innate and acquired immune responses. We suggest that turnstones could have evolved strong immune responses because they scavenge among rotting organic material on the seashore, where they might be exposed to a particularly broad range of pathogens. Although ruffs stand out among shorebirds in having a high prevalence of avian malaria, they do not exhibit higher immune response levels. Our results indicate that relationships between immune response and infection are not likely to follow a broad general pattern, but instead depend on type of parasite exposure, among other factors. Text Arenaria interpres Calidris alba Philomachus pugnax Red Knot Ruddy Turnstone Ruff Sanderling HighWire Press (Stanford University) Journal of Experimental Biology 209 2 284 291 |
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HighWire Press (Stanford University) |
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English |
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Research Article |
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Research Article Mendes, Luisa Piersma, Theunis Hasselquist, Dennis Matson, Kevin D. Ricklefs, Robert E. Variation in the innate and acquired arms of the immune system among five shorebird species |
topic_facet |
Research Article |
description |
To contribute to an understanding of the evolutionary processes that shape variation in immune responses, we compared several components of the innate and acquired arms of the immune system in five related, but ecologically diverse, migratory shorebirds (ruff Philomachus pugnax L., ruddy turnstone Arenaria interpres L., bar-tailed godwit Limosa lapponica L., sanderling Calidris alba Pallas and red knot C. canutus L.). We used a hemolysis-hemagglutination assay in free-living shorebirds to assess two of the innate components (natural antibodies and complement-mediated lysis), and a modified quantitative enzyme-linked immunosorbent assay in birds held in captivity to assess the acquired component (humoral antibodies against tetanus and diphtheria toxoid) of immunity. Ruddy turnstones showed the highest levels of both innate and acquired immune responses. We suggest that turnstones could have evolved strong immune responses because they scavenge among rotting organic material on the seashore, where they might be exposed to a particularly broad range of pathogens. Although ruffs stand out among shorebirds in having a high prevalence of avian malaria, they do not exhibit higher immune response levels. Our results indicate that relationships between immune response and infection are not likely to follow a broad general pattern, but instead depend on type of parasite exposure, among other factors. |
format |
Text |
author |
Mendes, Luisa Piersma, Theunis Hasselquist, Dennis Matson, Kevin D. Ricklefs, Robert E. |
author_facet |
Mendes, Luisa Piersma, Theunis Hasselquist, Dennis Matson, Kevin D. Ricklefs, Robert E. |
author_sort |
Mendes, Luisa |
title |
Variation in the innate and acquired arms of the immune system among five shorebird species |
title_short |
Variation in the innate and acquired arms of the immune system among five shorebird species |
title_full |
Variation in the innate and acquired arms of the immune system among five shorebird species |
title_fullStr |
Variation in the innate and acquired arms of the immune system among five shorebird species |
title_full_unstemmed |
Variation in the innate and acquired arms of the immune system among five shorebird species |
title_sort |
variation in the innate and acquired arms of the immune system among five shorebird species |
publisher |
Company of Biologists |
publishDate |
2006 |
url |
http://jeb.biologists.org/cgi/content/short/209/2/284 https://doi.org/10.1242/jeb.02015 |
genre |
Arenaria interpres Calidris alba Philomachus pugnax Red Knot Ruddy Turnstone Ruff Sanderling |
genre_facet |
Arenaria interpres Calidris alba Philomachus pugnax Red Knot Ruddy Turnstone Ruff Sanderling |
op_relation |
http://jeb.biologists.org/cgi/content/short/209/2/284 http://dx.doi.org/10.1242/jeb.02015 |
op_rights |
Copyright (C) 2006, Company of Biologists |
op_doi |
https://doi.org/10.1242/jeb.02015 |
container_title |
Journal of Experimental Biology |
container_volume |
209 |
container_issue |
2 |
container_start_page |
284 |
op_container_end_page |
291 |
_version_ |
1766354009220710400 |