The 2-Electron Reduction of Sperm Whale Ferryl Myoglobin by Ethanol
Upon the addition of hydrogen peroxide or ethyl hydroperoxide to sperm whale metmyoglobin (MbIII) in the presence of ethanol, MbIII was converted to oxymyo-globin (MbIIO 2 ) under aerobic conditions and carboxymyoglobin (MbIIcO) under CO-saturated conditions. MbIIO 2 and MbIICO were also formed when...
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1986
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fthighwire:oai:open-archive.highwire.org:jbiochem:100/2/499 2023-05-15T18:26:30+02:00 The 2-Electron Reduction of Sperm Whale Ferryl Myoglobin by Ethanol HARADA, Kazuo TAMURA, Mamoru YAMAZAKI, Isao 1986-01-01 00:00:00.0 text/html http://jb.oxfordjournals.org/cgi/content/short/100/2/499 en eng Oxford University Press http://jb.oxfordjournals.org/cgi/content/short/100/2/499 Copyright (C) 1986, Japanese Biochemical Society REGULAR PAPERS TEXT 1986 fthighwire 2013-05-27T14:04:35Z Upon the addition of hydrogen peroxide or ethyl hydroperoxide to sperm whale metmyoglobin (MbIII) in the presence of ethanol, MbIII was converted to oxymyo-globin (MbIIO 2 ) under aerobic conditions and carboxymyoglobin (MbIIcO) under CO-saturated conditions. MbIIO 2 and MbIICO were also formed when ethanol was added to ferryl myoglobin (MbIV) which had been formed from the reaction of MbIII with hydrogen peroxide. From the stoichiometry, the primary reaction was formulated as follows.Mbiv + ethanol → MbII + acetaldehyde The reaction was optimal at pH 7.0–7.5. Sperm whale ferryl myoglobin was reduced less effectively by methanol and n -butanol, but not at all by sec- and Terf -butanols. The reduction of ferryl hemoproteins by ethanol was slower with horse heart myoglobin and was not observed with bovine hemoglobin or horseradish peroxidase. Text Sperm whale HighWire Press (Stanford University) |
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Open Polar |
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HighWire Press (Stanford University) |
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fthighwire |
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English |
topic |
REGULAR PAPERS |
spellingShingle |
REGULAR PAPERS HARADA, Kazuo TAMURA, Mamoru YAMAZAKI, Isao The 2-Electron Reduction of Sperm Whale Ferryl Myoglobin by Ethanol |
topic_facet |
REGULAR PAPERS |
description |
Upon the addition of hydrogen peroxide or ethyl hydroperoxide to sperm whale metmyoglobin (MbIII) in the presence of ethanol, MbIII was converted to oxymyo-globin (MbIIO 2 ) under aerobic conditions and carboxymyoglobin (MbIIcO) under CO-saturated conditions. MbIIO 2 and MbIICO were also formed when ethanol was added to ferryl myoglobin (MbIV) which had been formed from the reaction of MbIII with hydrogen peroxide. From the stoichiometry, the primary reaction was formulated as follows.Mbiv + ethanol → MbII + acetaldehyde The reaction was optimal at pH 7.0–7.5. Sperm whale ferryl myoglobin was reduced less effectively by methanol and n -butanol, but not at all by sec- and Terf -butanols. The reduction of ferryl hemoproteins by ethanol was slower with horse heart myoglobin and was not observed with bovine hemoglobin or horseradish peroxidase. |
format |
Text |
author |
HARADA, Kazuo TAMURA, Mamoru YAMAZAKI, Isao |
author_facet |
HARADA, Kazuo TAMURA, Mamoru YAMAZAKI, Isao |
author_sort |
HARADA, Kazuo |
title |
The 2-Electron Reduction of Sperm Whale Ferryl Myoglobin by Ethanol |
title_short |
The 2-Electron Reduction of Sperm Whale Ferryl Myoglobin by Ethanol |
title_full |
The 2-Electron Reduction of Sperm Whale Ferryl Myoglobin by Ethanol |
title_fullStr |
The 2-Electron Reduction of Sperm Whale Ferryl Myoglobin by Ethanol |
title_full_unstemmed |
The 2-Electron Reduction of Sperm Whale Ferryl Myoglobin by Ethanol |
title_sort |
2-electron reduction of sperm whale ferryl myoglobin by ethanol |
publisher |
Oxford University Press |
publishDate |
1986 |
url |
http://jb.oxfordjournals.org/cgi/content/short/100/2/499 |
genre |
Sperm whale |
genre_facet |
Sperm whale |
op_relation |
http://jb.oxfordjournals.org/cgi/content/short/100/2/499 |
op_rights |
Copyright (C) 1986, Japanese Biochemical Society |
_version_ |
1766208470114107392 |