Contribution of Risk Factor Changes to the Decline in Coronary Incidence During the North Karelia Project: A Within-Community Analysis
Salonen J T (Department of Community Health and General Practice, University of Kuopio, Kuopio, Finland), Tuomilehto J, Nissinen A, Kaplan G A and Puska P. Contribution of risk factor changes to the decline in coronary incidence during the North Karelia Project: A within community analysis. Internat...
Published in: | International Journal of Epidemiology |
---|---|
Main Authors: | , , , , |
Format: | Text |
Language: | English |
Published: |
Oxford University Press
1989
|
Subjects: | |
Online Access: | http://ije.oxfordjournals.org/cgi/content/short/18/3/595 https://doi.org/10.1093/ije/18.3.595 |
id |
fthighwire:oai:open-archive.highwire.org:intjepid:18/3/595 |
---|---|
record_format |
openpolar |
spelling |
fthighwire:oai:open-archive.highwire.org:intjepid:18/3/595 2023-05-15T17:00:24+02:00 Contribution of Risk Factor Changes to the Decline in Coronary Incidence During the North Karelia Project: A Within-Community Analysis SALONEN, JUKKA T TUOMILEHTO, JAAKKO NISSINEN, AULIKKI KAPLAN, GEORGE A PUSKA, PEKKA 1989-09-01 00:00:00.0 text/html http://ije.oxfordjournals.org/cgi/content/short/18/3/595 https://doi.org/10.1093/ije/18.3.595 en eng Oxford University Press http://ije.oxfordjournals.org/cgi/content/short/18/3/595 http://dx.doi.org/10.1093/ije/18.3.595 Copyright (C) 1989, International Epidemiological Association Original Articles TEXT 1989 fthighwire https://doi.org/10.1093/ije/18.3.595 2007-06-23T21:21:29Z Salonen J T (Department of Community Health and General Practice, University of Kuopio, Kuopio, Finland), Tuomilehto J, Nissinen A, Kaplan G A and Puska P. Contribution of risk factor changes to the decline in coronary incidence during the North Karelia Project: A within community analysis. International Journal of Epidemiology , 1989, 18: 595–601. We investigated the contribution of risk factor changes to the decline in incidence of ischaemic heart disease between three five-year periods (1972–76, 1977–81, 1982–86) in a community-based cardiovascular disease (CVD) control programme, the North Karelia project. Random population samples of over 10000 people were examined in 1972, 1977 and 1982 and followed for five years. Population attributable benefits were estimated for each time period from reductions in excess risks associated with S–cholesterol, tobacco products per day and the mean of systolic and diastolic blood pressure which were entered in logistic models with age and sex. Changes in risk factors accounted in North Karelia for 89% and in the reference population for 20% of the decline in ischaemic heart disease from 1972–6 to 1977–81. In healthy people, risk factor reductions accounted in North Karelia for 100%, but in the reference population only for 23% of the decline. The decline was non-significant in both areas from 1977–81 to 1982–86. In subjects with either CVD or diabetes, there was no decline in North Karelia in either period, whereas 30% and 64% of the decline (ns) in the reference population in the two periods, respectively, was attributable to risk factor changes. These data suggest that although the decline in the incidence of ischaemic heart disease in North Karelia did not differ from that in the reference population it was largely attributable to risk factor reductions in the healthy population. The decline in the reference population appears to be associated with changes in lifestyle, secondary prevention activities and medical care. Text karelia* HighWire Press (Stanford University) Puska ENVELOPE(23.917,23.917,66.667,66.667) International Journal of Epidemiology 18 3 595 601 |
institution |
Open Polar |
collection |
HighWire Press (Stanford University) |
op_collection_id |
fthighwire |
language |
English |
topic |
Original Articles |
spellingShingle |
Original Articles SALONEN, JUKKA T TUOMILEHTO, JAAKKO NISSINEN, AULIKKI KAPLAN, GEORGE A PUSKA, PEKKA Contribution of Risk Factor Changes to the Decline in Coronary Incidence During the North Karelia Project: A Within-Community Analysis |
topic_facet |
Original Articles |
description |
Salonen J T (Department of Community Health and General Practice, University of Kuopio, Kuopio, Finland), Tuomilehto J, Nissinen A, Kaplan G A and Puska P. Contribution of risk factor changes to the decline in coronary incidence during the North Karelia Project: A within community analysis. International Journal of Epidemiology , 1989, 18: 595–601. We investigated the contribution of risk factor changes to the decline in incidence of ischaemic heart disease between three five-year periods (1972–76, 1977–81, 1982–86) in a community-based cardiovascular disease (CVD) control programme, the North Karelia project. Random population samples of over 10000 people were examined in 1972, 1977 and 1982 and followed for five years. Population attributable benefits were estimated for each time period from reductions in excess risks associated with S–cholesterol, tobacco products per day and the mean of systolic and diastolic blood pressure which were entered in logistic models with age and sex. Changes in risk factors accounted in North Karelia for 89% and in the reference population for 20% of the decline in ischaemic heart disease from 1972–6 to 1977–81. In healthy people, risk factor reductions accounted in North Karelia for 100%, but in the reference population only for 23% of the decline. The decline was non-significant in both areas from 1977–81 to 1982–86. In subjects with either CVD or diabetes, there was no decline in North Karelia in either period, whereas 30% and 64% of the decline (ns) in the reference population in the two periods, respectively, was attributable to risk factor changes. These data suggest that although the decline in the incidence of ischaemic heart disease in North Karelia did not differ from that in the reference population it was largely attributable to risk factor reductions in the healthy population. The decline in the reference population appears to be associated with changes in lifestyle, secondary prevention activities and medical care. |
format |
Text |
author |
SALONEN, JUKKA T TUOMILEHTO, JAAKKO NISSINEN, AULIKKI KAPLAN, GEORGE A PUSKA, PEKKA |
author_facet |
SALONEN, JUKKA T TUOMILEHTO, JAAKKO NISSINEN, AULIKKI KAPLAN, GEORGE A PUSKA, PEKKA |
author_sort |
SALONEN, JUKKA T |
title |
Contribution of Risk Factor Changes to the Decline in Coronary Incidence During the North Karelia Project: A Within-Community Analysis |
title_short |
Contribution of Risk Factor Changes to the Decline in Coronary Incidence During the North Karelia Project: A Within-Community Analysis |
title_full |
Contribution of Risk Factor Changes to the Decline in Coronary Incidence During the North Karelia Project: A Within-Community Analysis |
title_fullStr |
Contribution of Risk Factor Changes to the Decline in Coronary Incidence During the North Karelia Project: A Within-Community Analysis |
title_full_unstemmed |
Contribution of Risk Factor Changes to the Decline in Coronary Incidence During the North Karelia Project: A Within-Community Analysis |
title_sort |
contribution of risk factor changes to the decline in coronary incidence during the north karelia project: a within-community analysis |
publisher |
Oxford University Press |
publishDate |
1989 |
url |
http://ije.oxfordjournals.org/cgi/content/short/18/3/595 https://doi.org/10.1093/ije/18.3.595 |
long_lat |
ENVELOPE(23.917,23.917,66.667,66.667) |
geographic |
Puska |
geographic_facet |
Puska |
genre |
karelia* |
genre_facet |
karelia* |
op_relation |
http://ije.oxfordjournals.org/cgi/content/short/18/3/595 http://dx.doi.org/10.1093/ije/18.3.595 |
op_rights |
Copyright (C) 1989, International Epidemiological Association |
op_doi |
https://doi.org/10.1093/ije/18.3.595 |
container_title |
International Journal of Epidemiology |
container_volume |
18 |
container_issue |
3 |
container_start_page |
595 |
op_container_end_page |
601 |
_version_ |
1766053064678047744 |