Time to pregnancy as a function of male and female serum concentrations of 2,2'4,4'5,5'-hexachlorobiphenyl (CB-153) and 1,1-dichloro-2,2-bis (p-chlorophenyl)-ethylene (p,p'-DDE)
BACKGROUND: Persistent organochlorine pollutants (POP) may affect both the female and male reproductive system in animals as well as in humans. METHODS: Blood samples were collected from pregnant women and their partners from Greenland, Warsaw and Kharkiv, and from a cohort of Swedish fishermen’s wi...
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fthighwire:oai:open-archive.highwire.org:humrep:21/3/657 2023-05-15T16:28:08+02:00 Time to pregnancy as a function of male and female serum concentrations of 2,2'4,4'5,5'-hexachlorobiphenyl (CB-153) and 1,1-dichloro-2,2-bis (p-chlorophenyl)-ethylene (p,p'-DDE) Axmon, A. Thulstrup, A.-M. Rignell-Hydbom, A. Pedersen, H.S. Zvyezday, V. Ludwicki, J.K. Jönsson, B.A.G. Toft, G. Bonde, J.-P. Hagmar, L. and INUENDO 2006-03-01 00:00:00.0 text/html http://humrep.oxfordjournals.org/cgi/content/short/21/3/657 https://doi.org/10.1093/humrep/dei397 en eng Oxford University Press http://humrep.oxfordjournals.org/cgi/content/short/21/3/657 http://dx.doi.org/10.1093/humrep/dei397 Copyright (C) 2006, European Society of Human Reproduction and Embryology Reproductive Epidemiology TEXT 2006 fthighwire https://doi.org/10.1093/humrep/dei397 2007-06-25T02:33:21Z BACKGROUND: Persistent organochlorine pollutants (POP) may affect both the female and male reproductive system in animals as well as in humans. METHODS: Blood samples were collected from pregnant women and their partners from Greenland, Warsaw and Kharkiv, and from a cohort of Swedish fishermen’s wives. Blood samples were analysed for 2,2′,4,4′,5,5′-hexachlorobiphenyl (CB-153) and 1,1-dichloro-2,2-bis ( p -chlorophenyl)-ethylene ( p , p ′-DDE). Information on the participants’ fertility, measured as time to pregnancy (TTP), was collected. In total, 778 men and 1505 women were included in the analyses. RESULTS: The data from Warsaw, Kharkiv and the Swedish fishermen’s wives indicated no effect of either male or female exposure to POP on TTP. However, among men and women from Greenland, there seemed to be an association between serum concentrations of CB-153 and p , p ′-DDE and prolonged TTP. Due to the strong intra-individual correlation between CB-153 and p , p ′-DDE in the Greenlandic population, it was not possible to determine whether the risk was associated with CB-153 or p , p ′-DDE or was an interaction between the two compounds. CONCLUSIONS: The overall results of the present study create a somewhat ambiguous pattern, but give some support to the idea that dietary POP exposure might be harmful for couple fertility. Text Greenland greenlandic HighWire Press (Stanford University) Greenland Human Reproduction 21 3 657 665 |
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Open Polar |
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HighWire Press (Stanford University) |
op_collection_id |
fthighwire |
language |
English |
topic |
Reproductive Epidemiology |
spellingShingle |
Reproductive Epidemiology Axmon, A. Thulstrup, A.-M. Rignell-Hydbom, A. Pedersen, H.S. Zvyezday, V. Ludwicki, J.K. Jönsson, B.A.G. Toft, G. Bonde, J.-P. Hagmar, L. and INUENDO Time to pregnancy as a function of male and female serum concentrations of 2,2'4,4'5,5'-hexachlorobiphenyl (CB-153) and 1,1-dichloro-2,2-bis (p-chlorophenyl)-ethylene (p,p'-DDE) |
topic_facet |
Reproductive Epidemiology |
description |
BACKGROUND: Persistent organochlorine pollutants (POP) may affect both the female and male reproductive system in animals as well as in humans. METHODS: Blood samples were collected from pregnant women and their partners from Greenland, Warsaw and Kharkiv, and from a cohort of Swedish fishermen’s wives. Blood samples were analysed for 2,2′,4,4′,5,5′-hexachlorobiphenyl (CB-153) and 1,1-dichloro-2,2-bis ( p -chlorophenyl)-ethylene ( p , p ′-DDE). Information on the participants’ fertility, measured as time to pregnancy (TTP), was collected. In total, 778 men and 1505 women were included in the analyses. RESULTS: The data from Warsaw, Kharkiv and the Swedish fishermen’s wives indicated no effect of either male or female exposure to POP on TTP. However, among men and women from Greenland, there seemed to be an association between serum concentrations of CB-153 and p , p ′-DDE and prolonged TTP. Due to the strong intra-individual correlation between CB-153 and p , p ′-DDE in the Greenlandic population, it was not possible to determine whether the risk was associated with CB-153 or p , p ′-DDE or was an interaction between the two compounds. CONCLUSIONS: The overall results of the present study create a somewhat ambiguous pattern, but give some support to the idea that dietary POP exposure might be harmful for couple fertility. |
format |
Text |
author |
Axmon, A. Thulstrup, A.-M. Rignell-Hydbom, A. Pedersen, H.S. Zvyezday, V. Ludwicki, J.K. Jönsson, B.A.G. Toft, G. Bonde, J.-P. Hagmar, L. and INUENDO |
author_facet |
Axmon, A. Thulstrup, A.-M. Rignell-Hydbom, A. Pedersen, H.S. Zvyezday, V. Ludwicki, J.K. Jönsson, B.A.G. Toft, G. Bonde, J.-P. Hagmar, L. and INUENDO |
author_sort |
Axmon, A. |
title |
Time to pregnancy as a function of male and female serum concentrations of 2,2'4,4'5,5'-hexachlorobiphenyl (CB-153) and 1,1-dichloro-2,2-bis (p-chlorophenyl)-ethylene (p,p'-DDE) |
title_short |
Time to pregnancy as a function of male and female serum concentrations of 2,2'4,4'5,5'-hexachlorobiphenyl (CB-153) and 1,1-dichloro-2,2-bis (p-chlorophenyl)-ethylene (p,p'-DDE) |
title_full |
Time to pregnancy as a function of male and female serum concentrations of 2,2'4,4'5,5'-hexachlorobiphenyl (CB-153) and 1,1-dichloro-2,2-bis (p-chlorophenyl)-ethylene (p,p'-DDE) |
title_fullStr |
Time to pregnancy as a function of male and female serum concentrations of 2,2'4,4'5,5'-hexachlorobiphenyl (CB-153) and 1,1-dichloro-2,2-bis (p-chlorophenyl)-ethylene (p,p'-DDE) |
title_full_unstemmed |
Time to pregnancy as a function of male and female serum concentrations of 2,2'4,4'5,5'-hexachlorobiphenyl (CB-153) and 1,1-dichloro-2,2-bis (p-chlorophenyl)-ethylene (p,p'-DDE) |
title_sort |
time to pregnancy as a function of male and female serum concentrations of 2,2'4,4'5,5'-hexachlorobiphenyl (cb-153) and 1,1-dichloro-2,2-bis (p-chlorophenyl)-ethylene (p,p'-dde) |
publisher |
Oxford University Press |
publishDate |
2006 |
url |
http://humrep.oxfordjournals.org/cgi/content/short/21/3/657 https://doi.org/10.1093/humrep/dei397 |
geographic |
Greenland |
geographic_facet |
Greenland |
genre |
Greenland greenlandic |
genre_facet |
Greenland greenlandic |
op_relation |
http://humrep.oxfordjournals.org/cgi/content/short/21/3/657 http://dx.doi.org/10.1093/humrep/dei397 |
op_rights |
Copyright (C) 2006, European Society of Human Reproduction and Embryology |
op_doi |
https://doi.org/10.1093/humrep/dei397 |
container_title |
Human Reproduction |
container_volume |
21 |
container_issue |
3 |
container_start_page |
657 |
op_container_end_page |
665 |
_version_ |
1766017750736568320 |