n-3 polyunsaturated fatty acids are still underappreciated and underused post myocardial infarction

Interest in the possible cardio-protective effects of n-3 polyunsaturated fatty acids (n-3 PUFA) has existed since the late 1970s. Early observations in Greenland Eskimos and the Japanese population linked a fatty fish oil rich diet with lower rates of heart disease. Now there is good evidence that...

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Bibliographic Details
Published in:Heart
Main Authors: Khavandi, Ali, Khavandi, Kaivan, Greenstein, Adam, Karsch, Karl, Heagerty, Anthony
Format: Text
Language:English
Published: British Medical Journal Publishing Group 2009
Subjects:
Viewpoint
Greenland
eskimo*
Online Access:http://heart.bmj.com/cgi/content/short/hrt.2008.161430v1
https://doi.org/10.1136/hrt.2008.161430
Description
Summary:Interest in the possible cardio-protective effects of n-3 polyunsaturated fatty acids (n-3 PUFA) has existed since the late 1970s. Early observations in Greenland Eskimos and the Japanese population linked a fatty fish oil rich diet with lower rates of heart disease. Now there is good evidence that n-3 PUFA and specifically the Eicosapentaenoic acid (EPA) and docosahexenoic acid (DHA) subgroups confer protection from coronary heart disease (CHD). This benefit appears most pronounced on CHD mortality and sudden cardiac death, which is 50% lower in men who consume oily fish at least once a week1. Multiple epidemiological studies have repeatedly confirmed this trend and suggest an inverse relationship between n-3 PUFA containing fish consumption and CHD death2-4.

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