Regional differences in the prevalence of pre-eclampsia in relation to the risk factors for coronary artery disease in women in Finland
Aims The aim of this study was to examine the prevalence of pre-eclampsia in Southern, Eastern, and Northern Finland, and the relationship between history of pre-eclampsia and maternal coronary artery disease (CAD) risk factors. Methods and results Women aged 25–64 years, who participated in a cross...
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2005
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fthighwire:oai:open-archive.highwire.org:ehj:26/1/44 2023-05-15T17:42:20+02:00 Regional differences in the prevalence of pre-eclampsia in relation to the risk factors for coronary artery disease in women in Finland Kaaja, Risto Kinnunen, Tarja Luoto, Riitta 2005-01-01 00:00:00.0 text/html http://eurheartj.oxfordjournals.org/cgi/content/short/26/1/44 https://doi.org/10.1093/eurheartj/ehi015 en eng Oxford University Press http://eurheartj.oxfordjournals.org/cgi/content/short/26/1/44 http://dx.doi.org/10.1093/eurheartj/ehi015 Copyright (C) 2005, European Society of Cardiology Clinical research TEXT 2005 fthighwire https://doi.org/10.1093/eurheartj/ehi015 2013-05-27T00:40:43Z Aims The aim of this study was to examine the prevalence of pre-eclampsia in Southern, Eastern, and Northern Finland, and the relationship between history of pre-eclampsia and maternal coronary artery disease (CAD) risk factors. Methods and results Women aged 25–64 years, who participated in a cross-sectional population survey and had been pregnant ( n =3650), were studied. The proportion of women who had ever had pre-eclampsia was lower in Southern (7.9%) compared with Northern Finland (13.9%) ( P =0.001), but did not differ from Eastern Finland (11.1%). In the logistic regression model, the age-adjusted prevalence of pre-eclampsia was 1.92-fold in Northern (95% CI: 1.46–2.53, P <0.001) and 1.47-fold in Eastern Finland (95% CI: 1.11–1.96, P =0.008) compared with Southern Finland. The odds ratios (ORs) were 1.70 (95% CI: 1.21–2.38, P =0.002) and 1.16 (95% CI: 0.82–1.64, P =0.40), respectively, when adjusted for age at first birth, current age, parity, body mass index (BMI), increased blood cholesterol, hypertension, diabetes/impaired glucose tolerance, CAD, and mother's myocardial infarction. History of pre-eclampsia was associated with increased blood cholesterol, higher current BMI and blood pressure, and higher current prevalence of hypertension, diabetes/impaired glucose tolerance. Conclusions Pre-eclampsia is most prevalent in the Northern part of Finland and could only be partly explained by higher prevalence of CAD risk factors. Text Northern Finland HighWire Press (Stanford University) European Heart Journal 26 1 44 50 |
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English |
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Clinical research |
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Clinical research Kaaja, Risto Kinnunen, Tarja Luoto, Riitta Regional differences in the prevalence of pre-eclampsia in relation to the risk factors for coronary artery disease in women in Finland |
topic_facet |
Clinical research |
description |
Aims The aim of this study was to examine the prevalence of pre-eclampsia in Southern, Eastern, and Northern Finland, and the relationship between history of pre-eclampsia and maternal coronary artery disease (CAD) risk factors. Methods and results Women aged 25–64 years, who participated in a cross-sectional population survey and had been pregnant ( n =3650), were studied. The proportion of women who had ever had pre-eclampsia was lower in Southern (7.9%) compared with Northern Finland (13.9%) ( P =0.001), but did not differ from Eastern Finland (11.1%). In the logistic regression model, the age-adjusted prevalence of pre-eclampsia was 1.92-fold in Northern (95% CI: 1.46–2.53, P <0.001) and 1.47-fold in Eastern Finland (95% CI: 1.11–1.96, P =0.008) compared with Southern Finland. The odds ratios (ORs) were 1.70 (95% CI: 1.21–2.38, P =0.002) and 1.16 (95% CI: 0.82–1.64, P =0.40), respectively, when adjusted for age at first birth, current age, parity, body mass index (BMI), increased blood cholesterol, hypertension, diabetes/impaired glucose tolerance, CAD, and mother's myocardial infarction. History of pre-eclampsia was associated with increased blood cholesterol, higher current BMI and blood pressure, and higher current prevalence of hypertension, diabetes/impaired glucose tolerance. Conclusions Pre-eclampsia is most prevalent in the Northern part of Finland and could only be partly explained by higher prevalence of CAD risk factors. |
format |
Text |
author |
Kaaja, Risto Kinnunen, Tarja Luoto, Riitta |
author_facet |
Kaaja, Risto Kinnunen, Tarja Luoto, Riitta |
author_sort |
Kaaja, Risto |
title |
Regional differences in the prevalence of pre-eclampsia in relation to the risk factors for coronary artery disease in women in Finland |
title_short |
Regional differences in the prevalence of pre-eclampsia in relation to the risk factors for coronary artery disease in women in Finland |
title_full |
Regional differences in the prevalence of pre-eclampsia in relation to the risk factors for coronary artery disease in women in Finland |
title_fullStr |
Regional differences in the prevalence of pre-eclampsia in relation to the risk factors for coronary artery disease in women in Finland |
title_full_unstemmed |
Regional differences in the prevalence of pre-eclampsia in relation to the risk factors for coronary artery disease in women in Finland |
title_sort |
regional differences in the prevalence of pre-eclampsia in relation to the risk factors for coronary artery disease in women in finland |
publisher |
Oxford University Press |
publishDate |
2005 |
url |
http://eurheartj.oxfordjournals.org/cgi/content/short/26/1/44 https://doi.org/10.1093/eurheartj/ehi015 |
genre |
Northern Finland |
genre_facet |
Northern Finland |
op_relation |
http://eurheartj.oxfordjournals.org/cgi/content/short/26/1/44 http://dx.doi.org/10.1093/eurheartj/ehi015 |
op_rights |
Copyright (C) 2005, European Society of Cardiology |
op_doi |
https://doi.org/10.1093/eurheartj/ehi015 |
container_title |
European Heart Journal |
container_volume |
26 |
container_issue |
1 |
container_start_page |
44 |
op_container_end_page |
50 |
_version_ |
1766144173496336384 |