High and increasing prevalence of inflammatory bowel disease in Finland with a clear North-South difference
Background and aim: Inflammatory bowel disease (IBD) prevalence has increased and a North–South gradient has been reported. We estimated the nationwide prevalence of IBD, ulcerative colitis (UC) and Crohn's disease (CD) in 1993, and prevalence of IBD in 2008, and assessed the geographical distr...
Published in: | Journal of Crohn's and Colitis |
---|---|
Main Authors: | , , , , , |
Format: | Text |
Language: | English |
Published: |
Oxford University Press
2013
|
Subjects: | |
Online Access: | http://ecco-jcc.oxfordjournals.org/cgi/content/short/7/7/e256 https://doi.org/10.1016/j.crohns.2012.10.007 |
id |
fthighwire:oai:open-archive.highwire.org:eccojc:7/7/e256 |
---|---|
record_format |
openpolar |
spelling |
fthighwire:oai:open-archive.highwire.org:eccojc:7/7/e256 2023-05-15T17:42:38+02:00 High and increasing prevalence of inflammatory bowel disease in Finland with a clear North-South difference Jussila, Airi Virta, Lauri J. Salomaa, Veikko Mäki, Juhani Jula, Antti Färkkilä, Martti A. 2013-08-01 00:00:00.0 text/html http://ecco-jcc.oxfordjournals.org/cgi/content/short/7/7/e256 https://doi.org/10.1016/j.crohns.2012.10.007 en eng Oxford University Press http://ecco-jcc.oxfordjournals.org/cgi/content/short/7/7/e256 http://dx.doi.org/10.1016/j.crohns.2012.10.007 Copyright (C) 2013, Oxford University Press Regular Papers TEXT 2013 fthighwire https://doi.org/10.1016/j.crohns.2012.10.007 2016-11-16T18:09:57Z Background and aim: Inflammatory bowel disease (IBD) prevalence has increased and a North–South gradient has been reported. We estimated the nationwide prevalence of IBD, ulcerative colitis (UC) and Crohn's disease (CD) in 1993, and prevalence of IBD in 2008, and assessed the geographical distribution of IBD in Finland. In addition, we investigated the vitamin D levels in a study population from a large, nationally representative health examination survey, the Health 2000 Survey. Methods: The register study for prevalences included all patients who had special reimbursement of medications for IBD in the years 1993 (n = 10,958) and 2008 (31,703). The study for D-vitamin measurement consisted of 6134 persons who had participated in the Health 2000 Survey. Results: The nationwide point prevalence of IBD in 1993 was 216 per 100,000 inhabitants, and 595 in 2008. In 1993, the prevalence of UC (177) was fourfold higher than the prevalence of CD (38). The prevalence of IBD and UC in Finland increased from South to North. For CD, no geographical variation could be demonstrated. In the Health 2000 survey, vitamin D levels were lower in Northern than in Southern Finland. Conclusions: Finland belongs to high prevalence area of IBD and this prevalence has increased nearly threefold during the past 15 years. A clear North–South gradient has been shown for IBD and UC, but not for CD. Slightly lower vitamin D levels in Northern Finland may be associated with the observed higher prevalence of IBD there. Text Northern Finland HighWire Press (Stanford University) Journal of Crohn's and Colitis 7 7 e256 e262 |
institution |
Open Polar |
collection |
HighWire Press (Stanford University) |
op_collection_id |
fthighwire |
language |
English |
topic |
Regular Papers |
spellingShingle |
Regular Papers Jussila, Airi Virta, Lauri J. Salomaa, Veikko Mäki, Juhani Jula, Antti Färkkilä, Martti A. High and increasing prevalence of inflammatory bowel disease in Finland with a clear North-South difference |
topic_facet |
Regular Papers |
description |
Background and aim: Inflammatory bowel disease (IBD) prevalence has increased and a North–South gradient has been reported. We estimated the nationwide prevalence of IBD, ulcerative colitis (UC) and Crohn's disease (CD) in 1993, and prevalence of IBD in 2008, and assessed the geographical distribution of IBD in Finland. In addition, we investigated the vitamin D levels in a study population from a large, nationally representative health examination survey, the Health 2000 Survey. Methods: The register study for prevalences included all patients who had special reimbursement of medications for IBD in the years 1993 (n = 10,958) and 2008 (31,703). The study for D-vitamin measurement consisted of 6134 persons who had participated in the Health 2000 Survey. Results: The nationwide point prevalence of IBD in 1993 was 216 per 100,000 inhabitants, and 595 in 2008. In 1993, the prevalence of UC (177) was fourfold higher than the prevalence of CD (38). The prevalence of IBD and UC in Finland increased from South to North. For CD, no geographical variation could be demonstrated. In the Health 2000 survey, vitamin D levels were lower in Northern than in Southern Finland. Conclusions: Finland belongs to high prevalence area of IBD and this prevalence has increased nearly threefold during the past 15 years. A clear North–South gradient has been shown for IBD and UC, but not for CD. Slightly lower vitamin D levels in Northern Finland may be associated with the observed higher prevalence of IBD there. |
format |
Text |
author |
Jussila, Airi Virta, Lauri J. Salomaa, Veikko Mäki, Juhani Jula, Antti Färkkilä, Martti A. |
author_facet |
Jussila, Airi Virta, Lauri J. Salomaa, Veikko Mäki, Juhani Jula, Antti Färkkilä, Martti A. |
author_sort |
Jussila, Airi |
title |
High and increasing prevalence of inflammatory bowel disease in Finland with a clear North-South difference |
title_short |
High and increasing prevalence of inflammatory bowel disease in Finland with a clear North-South difference |
title_full |
High and increasing prevalence of inflammatory bowel disease in Finland with a clear North-South difference |
title_fullStr |
High and increasing prevalence of inflammatory bowel disease in Finland with a clear North-South difference |
title_full_unstemmed |
High and increasing prevalence of inflammatory bowel disease in Finland with a clear North-South difference |
title_sort |
high and increasing prevalence of inflammatory bowel disease in finland with a clear north-south difference |
publisher |
Oxford University Press |
publishDate |
2013 |
url |
http://ecco-jcc.oxfordjournals.org/cgi/content/short/7/7/e256 https://doi.org/10.1016/j.crohns.2012.10.007 |
genre |
Northern Finland |
genre_facet |
Northern Finland |
op_relation |
http://ecco-jcc.oxfordjournals.org/cgi/content/short/7/7/e256 http://dx.doi.org/10.1016/j.crohns.2012.10.007 |
op_rights |
Copyright (C) 2013, Oxford University Press |
op_doi |
https://doi.org/10.1016/j.crohns.2012.10.007 |
container_title |
Journal of Crohn's and Colitis |
container_volume |
7 |
container_issue |
7 |
container_start_page |
e256 |
op_container_end_page |
e262 |
_version_ |
1766144536328798208 |