Life-Threatening Haemophilus influenzae Infections in Scandinavia: A Five-Country Analysis of the Incidence and the Main Clinical and Bacteriologic Characteristics
The five countries of Scandinavia (Denmark, Finland, Iceland, Norway, and Sweden) comprise 22.6 million inhabitants and rather homogeneous socioeconomic conditions. A survey of systemic Haemophilus influenzae diseases over the last decades revealed that the reported incidence of H. influenzae diseas...
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Oxford University Press
1990
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fthighwire:oai:open-archive.highwire.org:cid:12/4/708 2023-05-15T16:50:12+02:00 Life-Threatening Haemophilus influenzae Infections in Scandinavia: A Five-Country Analysis of the Incidence and the Main Clinical and Bacteriologic Characteristics Peltola, Heikki Rød, Terje Olav Jónsdóttir, Kristin Bötttger, Margareta Coolidge, Jo Anna Stina 1990-07-01 00:00:00.0 text/html http://cid.oxfordjournals.org/cgi/content/short/12/4/708 https://doi.org/10.1093/clinids/12.4.708 en eng Oxford University Press http://cid.oxfordjournals.org/cgi/content/short/12/4/708 http://dx.doi.org/10.1093/clinids/12.4.708 Copyright (C) 1990, Infectious Diseases Society of America International Report TEXT 1990 fthighwire https://doi.org/10.1093/clinids/12.4.708 2013-05-27T00:02:29Z The five countries of Scandinavia (Denmark, Finland, Iceland, Norway, and Sweden) comprise 22.6 million inhabitants and rather homogeneous socioeconomic conditions. A survey of systemic Haemophilus influenzae diseases over the last decades revealed that the reported incidence of H. influenzae disease is increasing. In recent years, the overall incidence has been 3.5 cases per 100,000 people each year (800 cases annually); in children <5 years of age, the annual incidence has been 49 cases per 100,000. Meningitis represents only 52% of all systemic H. influenzae diseases, but lack of reliable data may obscure the importance of other entities. Few strains (<5%) are β-lactamase-positive, and the case fatality rate is 3%. Analysis of seasonal variation shows peaks in June and September–October. If the efficacy of the H. influenzae conjugate vaccines were as high as that of a conjugate vaccine used in Finland during 1986–1987 (∼85% efficacy), then at least an 80% reduction in life-threatening H. influenzae infections would be achieved annually by routine immunization before or at the age of 6 months. Text Iceland HighWire Press (Stanford University) Norway Clinical Infectious Diseases 12 4 708 715 |
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International Report |
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International Report Peltola, Heikki Rød, Terje Olav Jónsdóttir, Kristin Bötttger, Margareta Coolidge, Jo Anna Stina Life-Threatening Haemophilus influenzae Infections in Scandinavia: A Five-Country Analysis of the Incidence and the Main Clinical and Bacteriologic Characteristics |
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International Report |
description |
The five countries of Scandinavia (Denmark, Finland, Iceland, Norway, and Sweden) comprise 22.6 million inhabitants and rather homogeneous socioeconomic conditions. A survey of systemic Haemophilus influenzae diseases over the last decades revealed that the reported incidence of H. influenzae disease is increasing. In recent years, the overall incidence has been 3.5 cases per 100,000 people each year (800 cases annually); in children <5 years of age, the annual incidence has been 49 cases per 100,000. Meningitis represents only 52% of all systemic H. influenzae diseases, but lack of reliable data may obscure the importance of other entities. Few strains (<5%) are β-lactamase-positive, and the case fatality rate is 3%. Analysis of seasonal variation shows peaks in June and September–October. If the efficacy of the H. influenzae conjugate vaccines were as high as that of a conjugate vaccine used in Finland during 1986–1987 (∼85% efficacy), then at least an 80% reduction in life-threatening H. influenzae infections would be achieved annually by routine immunization before or at the age of 6 months. |
format |
Text |
author |
Peltola, Heikki Rød, Terje Olav Jónsdóttir, Kristin Bötttger, Margareta Coolidge, Jo Anna Stina |
author_facet |
Peltola, Heikki Rød, Terje Olav Jónsdóttir, Kristin Bötttger, Margareta Coolidge, Jo Anna Stina |
author_sort |
Peltola, Heikki |
title |
Life-Threatening Haemophilus influenzae Infections in Scandinavia: A Five-Country Analysis of the Incidence and the Main Clinical and Bacteriologic Characteristics |
title_short |
Life-Threatening Haemophilus influenzae Infections in Scandinavia: A Five-Country Analysis of the Incidence and the Main Clinical and Bacteriologic Characteristics |
title_full |
Life-Threatening Haemophilus influenzae Infections in Scandinavia: A Five-Country Analysis of the Incidence and the Main Clinical and Bacteriologic Characteristics |
title_fullStr |
Life-Threatening Haemophilus influenzae Infections in Scandinavia: A Five-Country Analysis of the Incidence and the Main Clinical and Bacteriologic Characteristics |
title_full_unstemmed |
Life-Threatening Haemophilus influenzae Infections in Scandinavia: A Five-Country Analysis of the Incidence and the Main Clinical and Bacteriologic Characteristics |
title_sort |
life-threatening haemophilus influenzae infections in scandinavia: a five-country analysis of the incidence and the main clinical and bacteriologic characteristics |
publisher |
Oxford University Press |
publishDate |
1990 |
url |
http://cid.oxfordjournals.org/cgi/content/short/12/4/708 https://doi.org/10.1093/clinids/12.4.708 |
geographic |
Norway |
geographic_facet |
Norway |
genre |
Iceland |
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Iceland |
op_relation |
http://cid.oxfordjournals.org/cgi/content/short/12/4/708 http://dx.doi.org/10.1093/clinids/12.4.708 |
op_rights |
Copyright (C) 1990, Infectious Diseases Society of America |
op_doi |
https://doi.org/10.1093/clinids/12.4.708 |
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Clinical Infectious Diseases |
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12 |
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4 |
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708 |
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715 |
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1766040378481311744 |