AN EPIDEMIC OF ECHOVIRUS TYPE 30 MENINGITIS IN AN ARCTIC COMMUNITY
In June of 1969, an epidemic of aseptic meningitis occurred in Bethel, Alaska. A total of 97 cases were identified; 40 were classified as aseptic meningitis and 57 as minor febrile illness. A random sample survey of 277 persons in a population of 2000 revealed an illness rate of 8.7%. The highest at...
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fthighwire:oai:open-archive.highwire.org:amjepid:99/5/368 2023-05-15T15:05:38+02:00 AN EPIDEMIC OF ECHOVIRUS TYPE 30 MENINGITIS IN AN ARCTIC COMMUNITY GRAVELLE, CLIFTON R. NOBLE, GARY R. FELTZ, ELMER T. SASLOW, ARNOLD R. CLARK, PAUL S. CHIN, TOM D. Y. 1974-05-01 00:00:00.0 text/html http://aje.oxfordjournals.org/cgi/content/short/99/5/368 en eng Oxford University Press http://aje.oxfordjournals.org/cgi/content/short/99/5/368 Copyright (C) 1974, Oxford University Press ORIGINAL CONTRIBUTIONS TEXT 1974 fthighwire 2016-11-16T18:22:16Z In June of 1969, an epidemic of aseptic meningitis occurred in Bethel, Alaska. A total of 97 cases were identified; 40 were classified as aseptic meningitis and 57 as minor febrile illness. A random sample survey of 277 persons in a population of 2000 revealed an illness rate of 8.7%. The highest attack rates were in children under 10 years of age. Evidence of infection with echovirus 30 was found by virus isolation or antibody rise in 69 of 78 (88%) ill persons and 83 of 112 (74%) well persons. Echovirus 30 was recovered from 2 of 18 spinal fluids with fewer than 50 leucocytes/cu mm and from 5 of 10 spinal fluids with more than 50 leucocytes. Pleocytosis was found in 11 of 16 persons who were not diagnosed as having aseptic meningitis. Pre-epidemic serum samples had been collected from 143 persons as part of a prospective family study of respiratory disease. Fourfold antibody rises between these and post-epidemic sera were considered evidence of infection in ill and well people; the ratio of clinical to subclinical infection thus calculated was 1: 2. Text Arctic Alaska HighWire Press (Stanford University) Arctic |
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HighWire Press (Stanford University) |
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English |
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ORIGINAL CONTRIBUTIONS |
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ORIGINAL CONTRIBUTIONS GRAVELLE, CLIFTON R. NOBLE, GARY R. FELTZ, ELMER T. SASLOW, ARNOLD R. CLARK, PAUL S. CHIN, TOM D. Y. AN EPIDEMIC OF ECHOVIRUS TYPE 30 MENINGITIS IN AN ARCTIC COMMUNITY |
topic_facet |
ORIGINAL CONTRIBUTIONS |
description |
In June of 1969, an epidemic of aseptic meningitis occurred in Bethel, Alaska. A total of 97 cases were identified; 40 were classified as aseptic meningitis and 57 as minor febrile illness. A random sample survey of 277 persons in a population of 2000 revealed an illness rate of 8.7%. The highest attack rates were in children under 10 years of age. Evidence of infection with echovirus 30 was found by virus isolation or antibody rise in 69 of 78 (88%) ill persons and 83 of 112 (74%) well persons. Echovirus 30 was recovered from 2 of 18 spinal fluids with fewer than 50 leucocytes/cu mm and from 5 of 10 spinal fluids with more than 50 leucocytes. Pleocytosis was found in 11 of 16 persons who were not diagnosed as having aseptic meningitis. Pre-epidemic serum samples had been collected from 143 persons as part of a prospective family study of respiratory disease. Fourfold antibody rises between these and post-epidemic sera were considered evidence of infection in ill and well people; the ratio of clinical to subclinical infection thus calculated was 1: 2. |
format |
Text |
author |
GRAVELLE, CLIFTON R. NOBLE, GARY R. FELTZ, ELMER T. SASLOW, ARNOLD R. CLARK, PAUL S. CHIN, TOM D. Y. |
author_facet |
GRAVELLE, CLIFTON R. NOBLE, GARY R. FELTZ, ELMER T. SASLOW, ARNOLD R. CLARK, PAUL S. CHIN, TOM D. Y. |
author_sort |
GRAVELLE, CLIFTON R. |
title |
AN EPIDEMIC OF ECHOVIRUS TYPE 30 MENINGITIS IN AN ARCTIC COMMUNITY |
title_short |
AN EPIDEMIC OF ECHOVIRUS TYPE 30 MENINGITIS IN AN ARCTIC COMMUNITY |
title_full |
AN EPIDEMIC OF ECHOVIRUS TYPE 30 MENINGITIS IN AN ARCTIC COMMUNITY |
title_fullStr |
AN EPIDEMIC OF ECHOVIRUS TYPE 30 MENINGITIS IN AN ARCTIC COMMUNITY |
title_full_unstemmed |
AN EPIDEMIC OF ECHOVIRUS TYPE 30 MENINGITIS IN AN ARCTIC COMMUNITY |
title_sort |
epidemic of echovirus type 30 meningitis in an arctic community |
publisher |
Oxford University Press |
publishDate |
1974 |
url |
http://aje.oxfordjournals.org/cgi/content/short/99/5/368 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic Alaska |
genre_facet |
Arctic Alaska |
op_relation |
http://aje.oxfordjournals.org/cgi/content/short/99/5/368 |
op_rights |
Copyright (C) 1974, Oxford University Press |
_version_ |
1766337294661320704 |