Glutathione S-Transferase M1 Genetic Polymorphism Is Associated With Salivary 17-βestradiol Levels: A Study Based On Hormonal Profiles From Entire Menstrual Cycles

• Published in: European Journal of Cancer Supplements
• Main Authors: Furberg, Anne-Sofie, McTiernan, Anne, Ellison, Peter, Makar, Karen W., Iversen, Amy, Emaus, Aina, Thune, Inger
• Language: English
• Published: Elsevier 2008
• Subjects: Norway; Tromsø; Ebba; North Norway
• Online Access: http://nrs.harvard.edu/urn-3:HUL.InstRepos:3008264; https://doi.org/10.1016/S1359-6349(08)71910-4

Introduction: Studies suggest that enzymes involved in the estrogen metabolic pathway are susceptibility factors for breast cancer; however, there is limited direct evidence in relation to estradiol levels. The glutathione-S-transferase M1 enzyme (GSTM1) enzyme is involved in estrogen peroxidation,...