Little evidence of human infection with equine influenza during the 2007 epizootic, Queensland, Australia
Background Equine influenza virus (EIV) is considered enzootic in Europe (except Iceland), Asia, North Africa, and North and South America. When EIV outbreaks occur they may severely impact the equine and tourist industries. Australia faced its first EIV outbreak beginning in August of 2007. The out...
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Online Access: | http://hdl.handle.net/10072/64957 https://doi.org/10.1016/j.jcv.2013.11.011 |
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ftgriffithuniv:oai:research-repository.griffith.edu.au:10072/64957 2023-05-15T16:51:23+02:00 Little evidence of human infection with equine influenza during the 2007 epizootic, Queensland, Australia J. Burnell, Fiona A. Holmes, Mark H. Roiko, Anne B. Lowe, John L. Heil, Gary K. White, Sarah C. Gray, Gregory 2014 http://hdl.handle.net/10072/64957 https://doi.org/10.1016/j.jcv.2013.11.011 English eng Elsevier BV Journal of Clinical Virology Biological Sciences not elsewhere classified Journal article 2014 ftgriffithuniv https://doi.org/10.1016/j.jcv.2013.11.011 2018-07-30T10:47:19Z Background Equine influenza virus (EIV) is considered enzootic in Europe (except Iceland), Asia, North Africa, and North and South America. When EIV outbreaks occur they may severely impact the equine and tourist industries. Australia faced its first EIV outbreak beginning in August of 2007. The outbreak was concentrated in New South Wales and Queensland, with more than 1400 confirmed EIV infections in horses during the first month. Rapid response from the equine industry and the federal government was successful and Australia was declared free from EIV by the end of 2007. Objectives This cross-sectional study was designed to examine associations between exposure to EIV-infected horses and evidence of EIV infection in humans. Study design Employing informed consent, between October 2007 and April 2008, 100 subjects (89 with horse exposures and 11 non-exposed) were enrolled during equine events and at the University of the Sunshine Coast. All subjects provided a blood sample and were asked to complete an online questionnaire including health history, animal exposure and demographic information. Sera samples were tested for the presence of antibodies against two H3N8 EIV strains using microneutralization, hemagglutination inhibition, and enzyme-linked lectin assays. Results Evidence for H3N8 infection was sparse, with only 9 study participants having any indication of H3N8 infection and the seroreactivity seen was low and easily explained by cross-reactions against human influenza strains or vaccines. Conclusions These data provide little evidence to support the premise that EIV infections occurred among humans exposed to EIV-infected horses during the 2007 Australian epizootic. No Full Text Article in Journal/Newspaper Iceland Griffith University: Griffith Research Online Queensland Journal of Clinical Virology 59 2 100 103 |
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Griffith University: Griffith Research Online |
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ftgriffithuniv |
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English |
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Biological Sciences not elsewhere classified |
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Biological Sciences not elsewhere classified J. Burnell, Fiona A. Holmes, Mark H. Roiko, Anne B. Lowe, John L. Heil, Gary K. White, Sarah C. Gray, Gregory Little evidence of human infection with equine influenza during the 2007 epizootic, Queensland, Australia |
topic_facet |
Biological Sciences not elsewhere classified |
description |
Background Equine influenza virus (EIV) is considered enzootic in Europe (except Iceland), Asia, North Africa, and North and South America. When EIV outbreaks occur they may severely impact the equine and tourist industries. Australia faced its first EIV outbreak beginning in August of 2007. The outbreak was concentrated in New South Wales and Queensland, with more than 1400 confirmed EIV infections in horses during the first month. Rapid response from the equine industry and the federal government was successful and Australia was declared free from EIV by the end of 2007. Objectives This cross-sectional study was designed to examine associations between exposure to EIV-infected horses and evidence of EIV infection in humans. Study design Employing informed consent, between October 2007 and April 2008, 100 subjects (89 with horse exposures and 11 non-exposed) were enrolled during equine events and at the University of the Sunshine Coast. All subjects provided a blood sample and were asked to complete an online questionnaire including health history, animal exposure and demographic information. Sera samples were tested for the presence of antibodies against two H3N8 EIV strains using microneutralization, hemagglutination inhibition, and enzyme-linked lectin assays. Results Evidence for H3N8 infection was sparse, with only 9 study participants having any indication of H3N8 infection and the seroreactivity seen was low and easily explained by cross-reactions against human influenza strains or vaccines. Conclusions These data provide little evidence to support the premise that EIV infections occurred among humans exposed to EIV-infected horses during the 2007 Australian epizootic. No Full Text |
format |
Article in Journal/Newspaper |
author |
J. Burnell, Fiona A. Holmes, Mark H. Roiko, Anne B. Lowe, John L. Heil, Gary K. White, Sarah C. Gray, Gregory |
author_facet |
J. Burnell, Fiona A. Holmes, Mark H. Roiko, Anne B. Lowe, John L. Heil, Gary K. White, Sarah C. Gray, Gregory |
author_sort |
J. Burnell, Fiona |
title |
Little evidence of human infection with equine influenza during the 2007 epizootic, Queensland, Australia |
title_short |
Little evidence of human infection with equine influenza during the 2007 epizootic, Queensland, Australia |
title_full |
Little evidence of human infection with equine influenza during the 2007 epizootic, Queensland, Australia |
title_fullStr |
Little evidence of human infection with equine influenza during the 2007 epizootic, Queensland, Australia |
title_full_unstemmed |
Little evidence of human infection with equine influenza during the 2007 epizootic, Queensland, Australia |
title_sort |
little evidence of human infection with equine influenza during the 2007 epizootic, queensland, australia |
publisher |
Elsevier BV |
publishDate |
2014 |
url |
http://hdl.handle.net/10072/64957 https://doi.org/10.1016/j.jcv.2013.11.011 |
geographic |
Queensland |
geographic_facet |
Queensland |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
Journal of Clinical Virology |
op_doi |
https://doi.org/10.1016/j.jcv.2013.11.011 |
container_title |
Journal of Clinical Virology |
container_volume |
59 |
container_issue |
2 |
container_start_page |
100 |
op_container_end_page |
103 |
_version_ |
1766041496416419840 |