Antioxidant and Anticholinesterase Assets and Liquid Chromatography-Mass Spectrometry Preface of Various Fresh-Water and Marine Macroalgae

• Published in: Pharmacognosy Magazine
• Main Authors: Tahir, Atici, Murat, Kartal, Ilkay, Orhan, Bilge, Sener, Mahmud, Abu-Asaker, Senol, FATMA SEZER
• Format: Article in Journal/Newspaper
• Language: English
• Published: 2009
• Subjects: Chara hispida
• Online Access: https://doi.org/10.4103/0973-1296.58147; https://avesis.gazi.edu.tr/publication/details/b6b26be1-db20-4b1d-aa23-2885bd73775a/oai

The ethanol extracts from the fresh-water algae; Chara hispida L., Cladophora glomerata (Dilw.) Kutz, C. fracta (Dilw.) Kutz, Spirogyra gratiana Transeau, Mougeotia sp. (C.A. Agardh), Vaucheria sessilis (Vauch.) De Candolle, Geminella mutabilis (Breb.) Wille, the fresh-water plants; Ranunculus rionii Lagger and Ceratophyllum demersum L., as well as the marine algae; Sciniaia furcellata (Turn.) J. Agardh, Dictyota dichotoma (Huds.) Lam., Padina vickersiae Hoyt, Halopteris scoparia (L.) Sauvagau, and the sea grass; Posidonia oceanica (L.) Dell. were assessed in vitro for their antioxidant and anti-acetylcholinesterase (AChE) activities. Antioxidant activity was evaluated by 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity test at 0.125, 0.25, 0.5, 1.0, and 2.0 mg ml(-1) and ferric-reducing antioxidant power assay (FRAP) at 0.5, 1.0, and 2.0 mg ml(-1) concentrations. Total phenolic contents of the extracts were determined using Folin-Ciocalteau's reagent. The extracts were further analyzed qualitatively by LC-DAD-MS. S. gratiana had the best antioxidant activity, followed by R. rionii. LC-DAD-MS showed rich gallic acid and its ethyl ester contents in S. gratiana, while prosperous vitamin C content has been detected in P. oceanica for the first time in this study. S. gratiana possessed the highest inhibition (42.5 +/- 2.28%) at 2.0 mg ml-1 against AChE.