The immune response of bats differs between pre-migration and migration seasons
Maintaining a competent immune system is energetically costly and thus immunity may be traded against other costly traits such as seasonal migration. Here, we tested in long-distance migratory Nathusius' pipistrelles (Pipistrellus nathusii), if selected branches of immunity are expressed differ...
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ftfuberlin:oai:refubium.fu-berlin.de:fub188/29296 2023-05-15T17:59:46+02:00 The immune response of bats differs between pre-migration and migration seasons Voigt, Christian C. Fritze, Marcus Lindecke, Oliver Costantini, David Petersons, Gunars Czirják, Gábor Á. 2020 11 Seiten application/pdf https://refubium.fu-berlin.de/handle/fub188/29296 https://doi.org/10.17169/refubium-29043 https://doi.org/10.1038/s41598-020-74473-3 eng eng https://refubium.fu-berlin.de/handle/fub188/29296 http://dx.doi.org/10.17169/refubium-29043 doi:10.1038/s41598-020-74473-3 https://creativecommons.org/licenses/by/4.0/ CC-BY oxidative stress costs immunology longevity defenses thrushes diseases flight ddc:570 doc-type:article 2020 ftfuberlin https://doi.org/10.17169/refubium-29043 https://doi.org/10.1038/s41598-020-74473-3 2022-05-15T20:48:29Z Maintaining a competent immune system is energetically costly and thus immunity may be traded against other costly traits such as seasonal migration. Here, we tested in long-distance migratory Nathusius' pipistrelles (Pipistrellus nathusii), if selected branches of immunity are expressed differently in response to the energy demands and oxidative stress of aerial migration. During the migration period, we observed higher baseline lymphocyte and lower neutrophil levels than during the pre-migration period, but no stronger response of cellular effectors to an antigen challenge. Baseline plasma haptoglobin, as a component of the humoral innate immunity, remained similar during both seasons, yet baseline plasma haptoglobin levels increased by a factor of 7.8 in migratory bats during an immune challenge, whereas they did not change during the pre-migration period. Oxidative stress was higher during migration than during pre-migration, yet there was no association between blood oxidative status and immune parameters, and immune challenge did not trigger any changes in oxidative stress, irrespective of season. Our findings suggest that humoral effectors of the acute phase response may play a stronger role in the first-line defense against infections for migrating bats compared to non-migrating bats. We conclude that Nathusius' pipistrelles allocate resources differently into the branches of their immune system, most likely following current demands resulting from tight energy budgets during migration. Article in Journal/Newspaper Pipistrellus nathusii Freie Universität Berlin: Refubium (FU Berlin) |
institution |
Open Polar |
collection |
Freie Universität Berlin: Refubium (FU Berlin) |
op_collection_id |
ftfuberlin |
language |
English |
topic |
oxidative stress costs immunology longevity defenses thrushes diseases flight ddc:570 |
spellingShingle |
oxidative stress costs immunology longevity defenses thrushes diseases flight ddc:570 Voigt, Christian C. Fritze, Marcus Lindecke, Oliver Costantini, David Petersons, Gunars Czirják, Gábor Á. The immune response of bats differs between pre-migration and migration seasons |
topic_facet |
oxidative stress costs immunology longevity defenses thrushes diseases flight ddc:570 |
description |
Maintaining a competent immune system is energetically costly and thus immunity may be traded against other costly traits such as seasonal migration. Here, we tested in long-distance migratory Nathusius' pipistrelles (Pipistrellus nathusii), if selected branches of immunity are expressed differently in response to the energy demands and oxidative stress of aerial migration. During the migration period, we observed higher baseline lymphocyte and lower neutrophil levels than during the pre-migration period, but no stronger response of cellular effectors to an antigen challenge. Baseline plasma haptoglobin, as a component of the humoral innate immunity, remained similar during both seasons, yet baseline plasma haptoglobin levels increased by a factor of 7.8 in migratory bats during an immune challenge, whereas they did not change during the pre-migration period. Oxidative stress was higher during migration than during pre-migration, yet there was no association between blood oxidative status and immune parameters, and immune challenge did not trigger any changes in oxidative stress, irrespective of season. Our findings suggest that humoral effectors of the acute phase response may play a stronger role in the first-line defense against infections for migrating bats compared to non-migrating bats. We conclude that Nathusius' pipistrelles allocate resources differently into the branches of their immune system, most likely following current demands resulting from tight energy budgets during migration. |
format |
Article in Journal/Newspaper |
author |
Voigt, Christian C. Fritze, Marcus Lindecke, Oliver Costantini, David Petersons, Gunars Czirják, Gábor Á. |
author_facet |
Voigt, Christian C. Fritze, Marcus Lindecke, Oliver Costantini, David Petersons, Gunars Czirják, Gábor Á. |
author_sort |
Voigt, Christian C. |
title |
The immune response of bats differs between pre-migration and migration seasons |
title_short |
The immune response of bats differs between pre-migration and migration seasons |
title_full |
The immune response of bats differs between pre-migration and migration seasons |
title_fullStr |
The immune response of bats differs between pre-migration and migration seasons |
title_full_unstemmed |
The immune response of bats differs between pre-migration and migration seasons |
title_sort |
immune response of bats differs between pre-migration and migration seasons |
publishDate |
2020 |
url |
https://refubium.fu-berlin.de/handle/fub188/29296 https://doi.org/10.17169/refubium-29043 https://doi.org/10.1038/s41598-020-74473-3 |
genre |
Pipistrellus nathusii |
genre_facet |
Pipistrellus nathusii |
op_relation |
https://refubium.fu-berlin.de/handle/fub188/29296 http://dx.doi.org/10.17169/refubium-29043 doi:10.1038/s41598-020-74473-3 |
op_rights |
https://creativecommons.org/licenses/by/4.0/ |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.17169/refubium-29043 https://doi.org/10.1038/s41598-020-74473-3 |
_version_ |
1766168640182288384 |