Data_Sheet_1_Mitochondrial Traits Previously Associated With Species Maximum Lifespan Do Not Correlate With Longevity Across Populations of the Bivalve Arctica islandica.docx
The mitochondrial oxidative stress theory of aging posits that membrane susceptibility to peroxidation and the organization of the electron transport system (ETS) linked with reactive oxygen species (ROS) generation are two main drivers of lifespan. While a clear correlation has been established fro...
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ftfrontimediafig:oai:figshare.com:article/9115727 2023-05-15T15:22:30+02:00 Data_Sheet_1_Mitochondrial Traits Previously Associated With Species Maximum Lifespan Do Not Correlate With Longevity Across Populations of the Bivalve Arctica islandica.docx Enrique Rodríguez Cyril Dégletagne Tory M. Hagen Doris Abele Pierre U. Blier 2019-07-26T12:41:24Z https://doi.org/10.3389/fphys.2019.00946.s001 https://figshare.com/articles/Data_Sheet_1_Mitochondrial_Traits_Previously_Associated_With_Species_Maximum_Lifespan_Do_Not_Correlate_With_Longevity_Across_Populations_of_the_Bivalve_Arctica_islandica_docx/9115727 unknown doi:10.3389/fphys.2019.00946.s001 https://figshare.com/articles/Data_Sheet_1_Mitochondrial_Traits_Previously_Associated_With_Species_Maximum_Lifespan_Do_Not_Correlate_With_Longevity_Across_Populations_of_the_Bivalve_Arctica_islandica_docx/9115727 CC BY 4.0 CC-BY Physiology Exercise Physiology Nutritional Physiology Reproduction Cell Physiology Systems Physiology Animal Physiology - Biophysics Animal Physiology - Cell Animal Physiology - Systems Comparative Physiology Physiology not elsewhere classified Arctica islandica bivalve aging model electron transport system mitochondria peroxidation index reactive oxygen species Dataset 2019 ftfrontimediafig https://doi.org/10.3389/fphys.2019.00946.s001 2019-08-07T23:01:53Z The mitochondrial oxidative stress theory of aging posits that membrane susceptibility to peroxidation and the organization of the electron transport system (ETS) linked with reactive oxygen species (ROS) generation are two main drivers of lifespan. While a clear correlation has been established from species comparative studies, the significance of these characteristics as potential modulators of lifespan divergences among populations of individual species is still to be tested. The bivalve Arctica islandica, the longest-lived non-colonial animal with a record lifespan of 507 years, possesses a lower mitochondrial peroxidation index (PI) and reduced H 2 O 2 efflux linked to complexes I and III activities than related species. Taking advantage of the wide variation in maximum reported longevities (MRL) among 6 European populations (36–507 years), we examined whether these two mitochondrial properties could explain differences in longevity. We report no relationship between membrane PI and MRL in populations of A. islandica, as well as a lack of intraspecific relationship between ETS complex activities and MRL. Individuals from brackish sites characterized by wide temperature and salinity windows had, however, markedly lower ETS enzyme activities relative to citrate synthase activity. Our results highlight environment-dependent remodeling of mitochondrial phenotypes. Dataset Arctica islandica Frontiers: Figshare |
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Frontiers: Figshare |
op_collection_id |
ftfrontimediafig |
language |
unknown |
topic |
Physiology Exercise Physiology Nutritional Physiology Reproduction Cell Physiology Systems Physiology Animal Physiology - Biophysics Animal Physiology - Cell Animal Physiology - Systems Comparative Physiology Physiology not elsewhere classified Arctica islandica bivalve aging model electron transport system mitochondria peroxidation index reactive oxygen species |
spellingShingle |
Physiology Exercise Physiology Nutritional Physiology Reproduction Cell Physiology Systems Physiology Animal Physiology - Biophysics Animal Physiology - Cell Animal Physiology - Systems Comparative Physiology Physiology not elsewhere classified Arctica islandica bivalve aging model electron transport system mitochondria peroxidation index reactive oxygen species Enrique Rodríguez Cyril Dégletagne Tory M. Hagen Doris Abele Pierre U. Blier Data_Sheet_1_Mitochondrial Traits Previously Associated With Species Maximum Lifespan Do Not Correlate With Longevity Across Populations of the Bivalve Arctica islandica.docx |
topic_facet |
Physiology Exercise Physiology Nutritional Physiology Reproduction Cell Physiology Systems Physiology Animal Physiology - Biophysics Animal Physiology - Cell Animal Physiology - Systems Comparative Physiology Physiology not elsewhere classified Arctica islandica bivalve aging model electron transport system mitochondria peroxidation index reactive oxygen species |
description |
The mitochondrial oxidative stress theory of aging posits that membrane susceptibility to peroxidation and the organization of the electron transport system (ETS) linked with reactive oxygen species (ROS) generation are two main drivers of lifespan. While a clear correlation has been established from species comparative studies, the significance of these characteristics as potential modulators of lifespan divergences among populations of individual species is still to be tested. The bivalve Arctica islandica, the longest-lived non-colonial animal with a record lifespan of 507 years, possesses a lower mitochondrial peroxidation index (PI) and reduced H 2 O 2 efflux linked to complexes I and III activities than related species. Taking advantage of the wide variation in maximum reported longevities (MRL) among 6 European populations (36–507 years), we examined whether these two mitochondrial properties could explain differences in longevity. We report no relationship between membrane PI and MRL in populations of A. islandica, as well as a lack of intraspecific relationship between ETS complex activities and MRL. Individuals from brackish sites characterized by wide temperature and salinity windows had, however, markedly lower ETS enzyme activities relative to citrate synthase activity. Our results highlight environment-dependent remodeling of mitochondrial phenotypes. |
format |
Dataset |
author |
Enrique Rodríguez Cyril Dégletagne Tory M. Hagen Doris Abele Pierre U. Blier |
author_facet |
Enrique Rodríguez Cyril Dégletagne Tory M. Hagen Doris Abele Pierre U. Blier |
author_sort |
Enrique Rodríguez |
title |
Data_Sheet_1_Mitochondrial Traits Previously Associated With Species Maximum Lifespan Do Not Correlate With Longevity Across Populations of the Bivalve Arctica islandica.docx |
title_short |
Data_Sheet_1_Mitochondrial Traits Previously Associated With Species Maximum Lifespan Do Not Correlate With Longevity Across Populations of the Bivalve Arctica islandica.docx |
title_full |
Data_Sheet_1_Mitochondrial Traits Previously Associated With Species Maximum Lifespan Do Not Correlate With Longevity Across Populations of the Bivalve Arctica islandica.docx |
title_fullStr |
Data_Sheet_1_Mitochondrial Traits Previously Associated With Species Maximum Lifespan Do Not Correlate With Longevity Across Populations of the Bivalve Arctica islandica.docx |
title_full_unstemmed |
Data_Sheet_1_Mitochondrial Traits Previously Associated With Species Maximum Lifespan Do Not Correlate With Longevity Across Populations of the Bivalve Arctica islandica.docx |
title_sort |
data_sheet_1_mitochondrial traits previously associated with species maximum lifespan do not correlate with longevity across populations of the bivalve arctica islandica.docx |
publishDate |
2019 |
url |
https://doi.org/10.3389/fphys.2019.00946.s001 https://figshare.com/articles/Data_Sheet_1_Mitochondrial_Traits_Previously_Associated_With_Species_Maximum_Lifespan_Do_Not_Correlate_With_Longevity_Across_Populations_of_the_Bivalve_Arctica_islandica_docx/9115727 |
genre |
Arctica islandica |
genre_facet |
Arctica islandica |
op_relation |
doi:10.3389/fphys.2019.00946.s001 https://figshare.com/articles/Data_Sheet_1_Mitochondrial_Traits_Previously_Associated_With_Species_Maximum_Lifespan_Do_Not_Correlate_With_Longevity_Across_Populations_of_the_Bivalve_Arctica_islandica_docx/9115727 |
op_rights |
CC BY 4.0 |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.3389/fphys.2019.00946.s001 |
_version_ |
1766353152095813632 |