Image_3_Lipidomics Reveals Seasonal Shifts in a Large-Bodied Hibernator, the Brown Bear.TIFF
Prior to winter, heterotherms retain polyunsaturated fatty acids (“PUFA”), resulting in enhanced energy savings during hibernation, through deeper and longer torpor bouts. Hibernating bears exhibit a less dramatic reduction (2–5°C) in body temperature, but lower their metabolism to a degree close to...
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ftfrontimediafig:oai:figshare.com:article/7988564 2023-05-15T18:42:06+02:00 Image_3_Lipidomics Reveals Seasonal Shifts in a Large-Bodied Hibernator, the Brown Bear.TIFF Sylvain Giroud Isabelle Chery Fabrice Bertile Justine Bertrand-Michel Georg Tascher Guillemette Gauquelin-Koch Jon M. Arnemo Jon E. Swenson Navinder J. Singh Etienne Lefai Alina L. Evans Chantal Simon Stéphane Blanc 2019-04-12T16:09:31Z https://doi.org/10.3389/fphys.2019.00389.s003 https://figshare.com/articles/Image_3_Lipidomics_Reveals_Seasonal_Shifts_in_a_Large-Bodied_Hibernator_the_Brown_Bear_TIFF/7988564 unknown doi:10.3389/fphys.2019.00389.s003 https://figshare.com/articles/Image_3_Lipidomics_Reveals_Seasonal_Shifts_in_a_Large-Bodied_Hibernator_the_Brown_Bear_TIFF/7988564 CC BY 4.0 CC-BY Physiology Exercise Physiology Nutritional Physiology Reproduction Cell Physiology Systems Physiology Animal Physiology - Biophysics Animal Physiology - Cell Animal Physiology - Systems Comparative Physiology Physiology not elsewhere classified hibernation body temperature metabolism fatty acids glycerophospholipids sphingomyelin ceramide Image Figure 2019 ftfrontimediafig https://doi.org/10.3389/fphys.2019.00389.s003 2019-04-17T22:59:18Z Prior to winter, heterotherms retain polyunsaturated fatty acids (“PUFA”), resulting in enhanced energy savings during hibernation, through deeper and longer torpor bouts. Hibernating bears exhibit a less dramatic reduction (2–5°C) in body temperature, but lower their metabolism to a degree close to that of small hibernators. We determined the lipid composition, via lipidomics, in skeletal muscle and white adipose tissues (“WAT”), to assess lipid retention, and in blood plasma, to reflect lipid trafficking, of winter hibernating and summer active wild Scandinavian brown bears (Ursus arctos). We found that the proportion of monounsaturated fatty acids in muscle of bears was significantly higher during winter. During hibernation, omega-3 PUFAs were retained in WAT and short-length fatty acids were released into the plasma. The analysis of individual lipid moieties indicated significant changes of specific fatty acids, which are in line with the observed seasonal shift in the major lipid categories and can be involved in specific regulations of metabolisms. These results strongly suggest that the shift in lipid composition is well conserved among hibernators, independent of body mass and of the animals’ body temperature. Still Image Ursus arctos Frontiers: Figshare |
institution |
Open Polar |
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Frontiers: Figshare |
op_collection_id |
ftfrontimediafig |
language |
unknown |
topic |
Physiology Exercise Physiology Nutritional Physiology Reproduction Cell Physiology Systems Physiology Animal Physiology - Biophysics Animal Physiology - Cell Animal Physiology - Systems Comparative Physiology Physiology not elsewhere classified hibernation body temperature metabolism fatty acids glycerophospholipids sphingomyelin ceramide |
spellingShingle |
Physiology Exercise Physiology Nutritional Physiology Reproduction Cell Physiology Systems Physiology Animal Physiology - Biophysics Animal Physiology - Cell Animal Physiology - Systems Comparative Physiology Physiology not elsewhere classified hibernation body temperature metabolism fatty acids glycerophospholipids sphingomyelin ceramide Sylvain Giroud Isabelle Chery Fabrice Bertile Justine Bertrand-Michel Georg Tascher Guillemette Gauquelin-Koch Jon M. Arnemo Jon E. Swenson Navinder J. Singh Etienne Lefai Alina L. Evans Chantal Simon Stéphane Blanc Image_3_Lipidomics Reveals Seasonal Shifts in a Large-Bodied Hibernator, the Brown Bear.TIFF |
topic_facet |
Physiology Exercise Physiology Nutritional Physiology Reproduction Cell Physiology Systems Physiology Animal Physiology - Biophysics Animal Physiology - Cell Animal Physiology - Systems Comparative Physiology Physiology not elsewhere classified hibernation body temperature metabolism fatty acids glycerophospholipids sphingomyelin ceramide |
description |
Prior to winter, heterotherms retain polyunsaturated fatty acids (“PUFA”), resulting in enhanced energy savings during hibernation, through deeper and longer torpor bouts. Hibernating bears exhibit a less dramatic reduction (2–5°C) in body temperature, but lower their metabolism to a degree close to that of small hibernators. We determined the lipid composition, via lipidomics, in skeletal muscle and white adipose tissues (“WAT”), to assess lipid retention, and in blood plasma, to reflect lipid trafficking, of winter hibernating and summer active wild Scandinavian brown bears (Ursus arctos). We found that the proportion of monounsaturated fatty acids in muscle of bears was significantly higher during winter. During hibernation, omega-3 PUFAs were retained in WAT and short-length fatty acids were released into the plasma. The analysis of individual lipid moieties indicated significant changes of specific fatty acids, which are in line with the observed seasonal shift in the major lipid categories and can be involved in specific regulations of metabolisms. These results strongly suggest that the shift in lipid composition is well conserved among hibernators, independent of body mass and of the animals’ body temperature. |
format |
Still Image |
author |
Sylvain Giroud Isabelle Chery Fabrice Bertile Justine Bertrand-Michel Georg Tascher Guillemette Gauquelin-Koch Jon M. Arnemo Jon E. Swenson Navinder J. Singh Etienne Lefai Alina L. Evans Chantal Simon Stéphane Blanc |
author_facet |
Sylvain Giroud Isabelle Chery Fabrice Bertile Justine Bertrand-Michel Georg Tascher Guillemette Gauquelin-Koch Jon M. Arnemo Jon E. Swenson Navinder J. Singh Etienne Lefai Alina L. Evans Chantal Simon Stéphane Blanc |
author_sort |
Sylvain Giroud |
title |
Image_3_Lipidomics Reveals Seasonal Shifts in a Large-Bodied Hibernator, the Brown Bear.TIFF |
title_short |
Image_3_Lipidomics Reveals Seasonal Shifts in a Large-Bodied Hibernator, the Brown Bear.TIFF |
title_full |
Image_3_Lipidomics Reveals Seasonal Shifts in a Large-Bodied Hibernator, the Brown Bear.TIFF |
title_fullStr |
Image_3_Lipidomics Reveals Seasonal Shifts in a Large-Bodied Hibernator, the Brown Bear.TIFF |
title_full_unstemmed |
Image_3_Lipidomics Reveals Seasonal Shifts in a Large-Bodied Hibernator, the Brown Bear.TIFF |
title_sort |
image_3_lipidomics reveals seasonal shifts in a large-bodied hibernator, the brown bear.tiff |
publishDate |
2019 |
url |
https://doi.org/10.3389/fphys.2019.00389.s003 https://figshare.com/articles/Image_3_Lipidomics_Reveals_Seasonal_Shifts_in_a_Large-Bodied_Hibernator_the_Brown_Bear_TIFF/7988564 |
genre |
Ursus arctos |
genre_facet |
Ursus arctos |
op_relation |
doi:10.3389/fphys.2019.00389.s003 https://figshare.com/articles/Image_3_Lipidomics_Reveals_Seasonal_Shifts_in_a_Large-Bodied_Hibernator_the_Brown_Bear_TIFF/7988564 |
op_rights |
CC BY 4.0 |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.3389/fphys.2019.00389.s003 |
_version_ |
1766231717707776000 |