Data_Sheet_1_IMGT® Biocuration and Comparative Study of the T Cell Receptor Beta Locus of Veterinary Species Based on Homo sapiens TRB.pdf
IMGT®, the international ImMunoGeneTics information system® is the global reference in immunogenetics and immunoinformatics. By its creation in 1989 by Marie-Paule Lefranc (Université de Montpellier and CNRS), IMGT® marked the advent of immunoinformatics, which emerged at the interface between immun...
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ftfrontimediafig:oai:figshare.com:article/12249179 2023-05-15T15:50:43+02:00 Data_Sheet_1_IMGT® Biocuration and Comparative Study of the T Cell Receptor Beta Locus of Veterinary Species Based on Homo sapiens TRB.pdf Perrine Pégorier Morgane Bertignac Imène Chentli Viviane Nguefack Ngoune Géraldine Folch Joumana Jabado-Michaloud Saida Hadi-Saljoqi Véronique Giudicelli Patrice Duroux Marie-Paule Lefranc Sofia Kossida 2020-05-05T12:40:51Z https://doi.org/10.3389/fimmu.2020.00821.s001 https://figshare.com/articles/Data_Sheet_1_IMGT_Biocuration_and_Comparative_Study_of_the_T_Cell_Receptor_Beta_Locus_of_Veterinary_Species_Based_on_Homo_sapiens_TRB_pdf/12249179 unknown doi:10.3389/fimmu.2020.00821.s001 https://figshare.com/articles/Data_Sheet_1_IMGT_Biocuration_and_Comparative_Study_of_the_T_Cell_Receptor_Beta_Locus_of_Veterinary_Species_Based_on_Homo_sapiens_TRB_pdf/12249179 CC BY 4.0 CC-BY Immunology Applied Immunology (incl. Antibody Engineering Xenotransplantation and T-cell Therapies) Autoimmunity Cellular Immunology Humoural Immunology and Immunochemistry Immunogenetics (incl. Genetic Immunology) Innate Immunity Transplantation Immunology Tumour Immunology Immunology not elsewhere classified Genetic Immunology Animal Immunology Veterinary Immunology IMGT immunoinformatics immunogenetics T cell receptor TRB locus Dataset 2020 ftfrontimediafig https://doi.org/10.3389/fimmu.2020.00821.s001 2020-05-06T22:53:28Z IMGT®, the international ImMunoGeneTics information system® is the global reference in immunogenetics and immunoinformatics. By its creation in 1989 by Marie-Paule Lefranc (Université de Montpellier and CNRS), IMGT® marked the advent of immunoinformatics, which emerged at the interface between immunogenetics and bioinformatics. IMGT® is specialized in the immunoglobulins (IG) or antibodies, T cell receptors (TR), major histocompatibility (MH), and proteins of the IgSF and MhSF superfamilies. T cell receptors are divided into two groups, αβ and γδ TR, which express distinct TR containing either α and β, or γ and δ chains, respectively. The TRβ locus (TRB) was recently described and annotated by IMGT® biocurators for several veterinary species, i.e., cat (Felis catus), dog (Canis lupus familiaris), ferret (Mustela putorius furo), pig (Sus scrofa), rabbit (Oryctolagus cuniculus), rhesus monkey (Macaca mulatta), and sheep (Ovis aries). The aim of the present study is to compare the genes of the TRB locus among these different veterinary species based on Homo sapiens. The results reveal that there are similarities but also differences including the number of genes by subgroup which may demonstrate duplications and/or deletions during evolution. Dataset Canis lupus Frontiers: Figshare |
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Frontiers: Figshare |
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ftfrontimediafig |
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unknown |
topic |
Immunology Applied Immunology (incl. Antibody Engineering Xenotransplantation and T-cell Therapies) Autoimmunity Cellular Immunology Humoural Immunology and Immunochemistry Immunogenetics (incl. Genetic Immunology) Innate Immunity Transplantation Immunology Tumour Immunology Immunology not elsewhere classified Genetic Immunology Animal Immunology Veterinary Immunology IMGT immunoinformatics immunogenetics T cell receptor TRB locus |
spellingShingle |
Immunology Applied Immunology (incl. Antibody Engineering Xenotransplantation and T-cell Therapies) Autoimmunity Cellular Immunology Humoural Immunology and Immunochemistry Immunogenetics (incl. Genetic Immunology) Innate Immunity Transplantation Immunology Tumour Immunology Immunology not elsewhere classified Genetic Immunology Animal Immunology Veterinary Immunology IMGT immunoinformatics immunogenetics T cell receptor TRB locus Perrine Pégorier Morgane Bertignac Imène Chentli Viviane Nguefack Ngoune Géraldine Folch Joumana Jabado-Michaloud Saida Hadi-Saljoqi Véronique Giudicelli Patrice Duroux Marie-Paule Lefranc Sofia Kossida Data_Sheet_1_IMGT® Biocuration and Comparative Study of the T Cell Receptor Beta Locus of Veterinary Species Based on Homo sapiens TRB.pdf |
topic_facet |
Immunology Applied Immunology (incl. Antibody Engineering Xenotransplantation and T-cell Therapies) Autoimmunity Cellular Immunology Humoural Immunology and Immunochemistry Immunogenetics (incl. Genetic Immunology) Innate Immunity Transplantation Immunology Tumour Immunology Immunology not elsewhere classified Genetic Immunology Animal Immunology Veterinary Immunology IMGT immunoinformatics immunogenetics T cell receptor TRB locus |
description |
IMGT®, the international ImMunoGeneTics information system® is the global reference in immunogenetics and immunoinformatics. By its creation in 1989 by Marie-Paule Lefranc (Université de Montpellier and CNRS), IMGT® marked the advent of immunoinformatics, which emerged at the interface between immunogenetics and bioinformatics. IMGT® is specialized in the immunoglobulins (IG) or antibodies, T cell receptors (TR), major histocompatibility (MH), and proteins of the IgSF and MhSF superfamilies. T cell receptors are divided into two groups, αβ and γδ TR, which express distinct TR containing either α and β, or γ and δ chains, respectively. The TRβ locus (TRB) was recently described and annotated by IMGT® biocurators for several veterinary species, i.e., cat (Felis catus), dog (Canis lupus familiaris), ferret (Mustela putorius furo), pig (Sus scrofa), rabbit (Oryctolagus cuniculus), rhesus monkey (Macaca mulatta), and sheep (Ovis aries). The aim of the present study is to compare the genes of the TRB locus among these different veterinary species based on Homo sapiens. The results reveal that there are similarities but also differences including the number of genes by subgroup which may demonstrate duplications and/or deletions during evolution. |
format |
Dataset |
author |
Perrine Pégorier Morgane Bertignac Imène Chentli Viviane Nguefack Ngoune Géraldine Folch Joumana Jabado-Michaloud Saida Hadi-Saljoqi Véronique Giudicelli Patrice Duroux Marie-Paule Lefranc Sofia Kossida |
author_facet |
Perrine Pégorier Morgane Bertignac Imène Chentli Viviane Nguefack Ngoune Géraldine Folch Joumana Jabado-Michaloud Saida Hadi-Saljoqi Véronique Giudicelli Patrice Duroux Marie-Paule Lefranc Sofia Kossida |
author_sort |
Perrine Pégorier |
title |
Data_Sheet_1_IMGT® Biocuration and Comparative Study of the T Cell Receptor Beta Locus of Veterinary Species Based on Homo sapiens TRB.pdf |
title_short |
Data_Sheet_1_IMGT® Biocuration and Comparative Study of the T Cell Receptor Beta Locus of Veterinary Species Based on Homo sapiens TRB.pdf |
title_full |
Data_Sheet_1_IMGT® Biocuration and Comparative Study of the T Cell Receptor Beta Locus of Veterinary Species Based on Homo sapiens TRB.pdf |
title_fullStr |
Data_Sheet_1_IMGT® Biocuration and Comparative Study of the T Cell Receptor Beta Locus of Veterinary Species Based on Homo sapiens TRB.pdf |
title_full_unstemmed |
Data_Sheet_1_IMGT® Biocuration and Comparative Study of the T Cell Receptor Beta Locus of Veterinary Species Based on Homo sapiens TRB.pdf |
title_sort |
data_sheet_1_imgt® biocuration and comparative study of the t cell receptor beta locus of veterinary species based on homo sapiens trb.pdf |
publishDate |
2020 |
url |
https://doi.org/10.3389/fimmu.2020.00821.s001 https://figshare.com/articles/Data_Sheet_1_IMGT_Biocuration_and_Comparative_Study_of_the_T_Cell_Receptor_Beta_Locus_of_Veterinary_Species_Based_on_Homo_sapiens_TRB_pdf/12249179 |
genre |
Canis lupus |
genre_facet |
Canis lupus |
op_relation |
doi:10.3389/fimmu.2020.00821.s001 https://figshare.com/articles/Data_Sheet_1_IMGT_Biocuration_and_Comparative_Study_of_the_T_Cell_Receptor_Beta_Locus_of_Veterinary_Species_Based_on_Homo_sapiens_TRB_pdf/12249179 |
op_rights |
CC BY 4.0 |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.3389/fimmu.2020.00821.s001 |
_version_ |
1766385716053409792 |