HEALTH ASSESSMENT DOCUMENT FOR PHOSGENE. EXTERNAL REVIEW DRAFT
Phosgene is primarily manufactured for the synthesis of isocyanate-based polymers, carbonic acid esters, and acid chlorides. Ambient and indoor air concentrations of phosgene are produced by direct emissions during its manufacture, handling, and use; thermal decomposition of chlorinated hydrocarbons...
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ftepa:oai:epaEIMS:41270 2023-05-15T15:52:35+02:00 HEALTH ASSESSMENT DOCUMENT FOR PHOSGENE. EXTERNAL REVIEW DRAFT N.P. Hajjar C.E. Rothwell L. Borghi B. Shacter C. Alexander 2006-09-05T17:43:16Z http://oaspub.epa.gov/eims/eimsapi.dispdetail?deid=41270 unknown NATIONAL CENTER FOR ENVIRONMENTAL ASSESSMENT Text 2006 ftepa 2007-11-21T13:49:24Z Phosgene is primarily manufactured for the synthesis of isocyanate-based polymers, carbonic acid esters, and acid chlorides. Ambient and indoor air concentrations of phosgene are produced by direct emissions during its manufacture, handling, and use; thermal decomposition of chlorinated hydrocarbons; and photochemical oxidation of chloroethylenes in the air. The effects of acute inhalation exposure are primarily respiratory, causing pulmonary emphysema, pulmonary edema, and possibly death due to paralysis of the respiratory center as a result of anoxia. Limited epidemiology studies indicate no increase in the incidence of cancers among workers chronically exposed to phosgene. No definitive conclusions can be drawn regarding possible teratogenic, reproductive, carcinogenic, or mutagenic effects of phosgene exposure because adequate studies have not been performed. Text Carbonic acid Environmental Protection Agency (EPA): Science Inventory |
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Environmental Protection Agency (EPA): Science Inventory |
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Phosgene is primarily manufactured for the synthesis of isocyanate-based polymers, carbonic acid esters, and acid chlorides. Ambient and indoor air concentrations of phosgene are produced by direct emissions during its manufacture, handling, and use; thermal decomposition of chlorinated hydrocarbons; and photochemical oxidation of chloroethylenes in the air. The effects of acute inhalation exposure are primarily respiratory, causing pulmonary emphysema, pulmonary edema, and possibly death due to paralysis of the respiratory center as a result of anoxia. Limited epidemiology studies indicate no increase in the incidence of cancers among workers chronically exposed to phosgene. No definitive conclusions can be drawn regarding possible teratogenic, reproductive, carcinogenic, or mutagenic effects of phosgene exposure because adequate studies have not been performed. |
format |
Text |
author |
N.P. Hajjar C.E. Rothwell L. Borghi B. Shacter C. Alexander |
spellingShingle |
N.P. Hajjar C.E. Rothwell L. Borghi B. Shacter C. Alexander HEALTH ASSESSMENT DOCUMENT FOR PHOSGENE. EXTERNAL REVIEW DRAFT |
author_facet |
N.P. Hajjar C.E. Rothwell L. Borghi B. Shacter C. Alexander |
author_sort |
N.P. Hajjar |
title |
HEALTH ASSESSMENT DOCUMENT FOR PHOSGENE. EXTERNAL REVIEW DRAFT |
title_short |
HEALTH ASSESSMENT DOCUMENT FOR PHOSGENE. EXTERNAL REVIEW DRAFT |
title_full |
HEALTH ASSESSMENT DOCUMENT FOR PHOSGENE. EXTERNAL REVIEW DRAFT |
title_fullStr |
HEALTH ASSESSMENT DOCUMENT FOR PHOSGENE. EXTERNAL REVIEW DRAFT |
title_full_unstemmed |
HEALTH ASSESSMENT DOCUMENT FOR PHOSGENE. EXTERNAL REVIEW DRAFT |
title_sort |
health assessment document for phosgene. external review draft |
publishDate |
2006 |
url |
http://oaspub.epa.gov/eims/eimsapi.dispdetail?deid=41270 |
genre |
Carbonic acid |
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Carbonic acid |
op_source |
NATIONAL CENTER FOR ENVIRONMENTAL ASSESSMENT |
_version_ |
1766387716220518400 |