Comparative Genomics of Tenacibaculum dicentrarchi and “Tenacibaculum finnmarkense” Highlights Intricate Evolution of Fish-Pathogenic Species

• Published in: Genome Biology and Evolution
• Main Authors: Bridel, Sébastien, Olsen, Anne-Berit, Nilsen, Hanne, Bernardet, Jean-François, Achaz, Guillaume, Avendaño-Herrera, Ruben, Duchaud, Éric
• Other Authors: Unité de recherche Virologie et Immunologie Moléculaires (VIM (UR 0892)), Institut National de la Recherche Agronomique (INRA), FINALAB, Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Norwegian Veterinary Institute Oslo ( NVI), Institut de Systématique, Evolution, Biodiversité (ISYEB ), Muséum national d'Histoire naturelle (MNHN)-Université Pierre et Marie Curie - Paris 6 (UPMC)-École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Centre National de la Recherche Scientifique (CNRS), Centre interdisciplinaire de recherche en biologie (CIRB), Labex MemoLife, École normale supérieure - Paris (ENS-PSL), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Collège de France (CdF (institution))-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris Sciences et Lettres (PSL)-École normale supérieure - Paris (ENS-PSL), Université Paris Sciences et Lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Universidad Andrés Bello Santiago (UNAB), Universidad de Concepción - University of Concepcion Chile, EU EMIDA ERA-NET project "Control Flavobacteriaceae Infections in European Fish farms", Agence Nationale pour la Recherche ANR-14-CE19-0020, National Infrastructure "France Genomique" funded as part of the Investissement d'avenir program managed by Agence Nationale pour la Recherche ANR-10-INBS-09, Comision Nacional de Investigacion Cientifica y Tecnologica (CONICYT, Chile) FONDECYT 1150695, CONICYT/FONDAP/15110027
• Format: Article in Journal/Newspaper
• Language: English
• Published: HAL CCSD 2018
• Subjects: Tenacibaculum; tenacibaculosis; genomes; fish pathogens; virulence; evolution; [SDV]Life Sciences [q-bio]; Norway; Atlantic salmon
• Online Access: https://hal.sorbonne-universite.fr/hal-01744087; https://hal.sorbonne-universite.fr/hal-01744087/document; https://hal.sorbonne-universite.fr/hal-01744087/file/evy020.pdf; https://doi.org/10.1093/gbe/evy020

Data deposition: All genome sequencing data have been deposited at the European Nucleotide Archive under the accessions GCA_900239455, GCA_900239305, GCA_900239485, GCA_900239185, GCA_900239505, GCA_900239345, and GCA_900239495. International audience The genus Tenacibaculum encompasses several species pathogenic for marine fish. Tenacibaculum dicentrarchi and " Tenacibaculum finnmarkense " (Quotation marks denote species that have not been validly named.) were retrieved from skin lesions of farmed fish such as European sea bass or Atlantic salmon. They cause a condition referred to as tenacibaculosis and severe outbreaks and important fish losses have been reported in Spanish, Norwegian, and Chilean marine farms. We report here the draft genomes of the T. dicentrarchi and " T. finnmarkense " type strains. These genomes were compared with draft genomes from field isolates retrieved from Chile and Norway and with previously published Tenacibaculum genomes. We used Average Nucleotide Identity and core genome-based phylogeny as a proxy index for species boundary delineation. This work highlights evolution of closely related fish-pathogenic species and suggests that homologous recombination likely contributes to genome evolution.