Genomic islands and the evolution of catabolic pathways in bacteria
Genes for the degradation of organic pollutants have usually been allocated to plasmid DNAs in bacteria or considered non-mobile when detected in the chromosome. New discoveries have shown that catabolic genes can also be part of so-called integrative and conjugative elements (ICElands), a group of...
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Online Access: | https://doi.org/10.1016/S0958-1669(03)00058-2 |
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fteawag:oai:dora:eawag_4543 2023-05-15T16:49:14+02:00 Genomic islands and the evolution of catabolic pathways in bacteria van der Meer, Jan Roelof Sentchilo, Vladimir 2003 https://doi.org/10.1016/S0958-1669(03)00058-2 eng eng Elsevier Current Opinion in Biotechnology--Curr. Opin. Biotechnol.--journals:660--0958-1669 eawag:4543 journal id: journals:660 issn: 0958-1669 ut: 000184225800002 local: 9120 scopus: 2-s2.0-0038504021 doi:10.1016/S0958-1669(03)00058-2 Text Journal Article 2003 fteawag https://doi.org/10.1016/S0958-1669(03)00058-2 2023-04-09T04:48:09Z Genes for the degradation of organic pollutants have usually been allocated to plasmid DNAs in bacteria or considered non-mobile when detected in the chromosome. New discoveries have shown that catabolic genes can also be part of so-called integrative and conjugative elements (ICElands), a group of mobile DNA elements also known as genomic islands and conjugative transposons. One such ICEland is the clc element for chlorobenzoate and chlorocatechol degradation in Pseudomonas sp. strain B13. Genome comparisons and genetic data on integrase functioning reveal that the clc element and several other unclassified ICElands belong to a group of elements with conserved features. The clc element is unique among them in carrying the genetic information for several degradation pathways, whereas the others give evidence for pathogenicity functions. Many more such elements may exist, bridging the gap between pathogenicity and degradation functions. Article in Journal/Newspaper Iceland DORA Eawag Current Opinion in Biotechnology 14 3 248 254 |
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English |
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Genes for the degradation of organic pollutants have usually been allocated to plasmid DNAs in bacteria or considered non-mobile when detected in the chromosome. New discoveries have shown that catabolic genes can also be part of so-called integrative and conjugative elements (ICElands), a group of mobile DNA elements also known as genomic islands and conjugative transposons. One such ICEland is the clc element for chlorobenzoate and chlorocatechol degradation in Pseudomonas sp. strain B13. Genome comparisons and genetic data on integrase functioning reveal that the clc element and several other unclassified ICElands belong to a group of elements with conserved features. The clc element is unique among them in carrying the genetic information for several degradation pathways, whereas the others give evidence for pathogenicity functions. Many more such elements may exist, bridging the gap between pathogenicity and degradation functions. |
format |
Article in Journal/Newspaper |
author |
van der Meer, Jan Roelof Sentchilo, Vladimir |
spellingShingle |
van der Meer, Jan Roelof Sentchilo, Vladimir Genomic islands and the evolution of catabolic pathways in bacteria |
author_facet |
van der Meer, Jan Roelof Sentchilo, Vladimir |
author_sort |
van der Meer, Jan Roelof |
title |
Genomic islands and the evolution of catabolic pathways in bacteria |
title_short |
Genomic islands and the evolution of catabolic pathways in bacteria |
title_full |
Genomic islands and the evolution of catabolic pathways in bacteria |
title_fullStr |
Genomic islands and the evolution of catabolic pathways in bacteria |
title_full_unstemmed |
Genomic islands and the evolution of catabolic pathways in bacteria |
title_sort |
genomic islands and the evolution of catabolic pathways in bacteria |
publisher |
Elsevier |
publishDate |
2003 |
url |
https://doi.org/10.1016/S0958-1669(03)00058-2 |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
Current Opinion in Biotechnology--Curr. Opin. Biotechnol.--journals:660--0958-1669 eawag:4543 journal id: journals:660 issn: 0958-1669 ut: 000184225800002 local: 9120 scopus: 2-s2.0-0038504021 doi:10.1016/S0958-1669(03)00058-2 |
op_doi |
https://doi.org/10.1016/S0958-1669(03)00058-2 |
container_title |
Current Opinion in Biotechnology |
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14 |
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3 |
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248 |
op_container_end_page |
254 |
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1766039395680387072 |