Inter-Species Transmission of Viral Haemorrhagic Septicaemia Virus Between Turbot (Scophthalmus Maximus) and Rainbow Trout (Onchorhynchus Mykiss)
Viral haemorrhagic septicaemia is a serious viral disease of teleost fish with high economic impact on the aquaculture industry. The disease is caused by the viral haemorrhagic septicaemia virus (VHSV), an RNA virus belonging to the family Rhabdoviridae. Compared to other rhabdoviruses infecting fis...
Main Authors: | , , |
---|---|
Format: | Conference Object |
Language: | English |
Published: |
University of Copenhagen
2012
|
Subjects: | |
Online Access: | https://orbit.dtu.dk/en/publications/e15b51a5-df97-42e4-a296-fb6339008288 http://www.dafinet.dk/DAFINET/Home_files/DAFINET%20November%206-7%202012%20Abstractbook.pdf |
id |
ftdtupubl:oai:pure.atira.dk:publications/e15b51a5-df97-42e4-a296-fb6339008288 |
---|---|
record_format |
openpolar |
spelling |
ftdtupubl:oai:pure.atira.dk:publications/e15b51a5-df97-42e4-a296-fb6339008288 2023-05-15T18:15:52+02:00 Inter-Species Transmission of Viral Haemorrhagic Septicaemia Virus Between Turbot (Scophthalmus Maximus) and Rainbow Trout (Onchorhynchus Mykiss) Schönherz, A. A. Lorenzen, Niels Einer-Jensen, Katja 2012 https://orbit.dtu.dk/en/publications/e15b51a5-df97-42e4-a296-fb6339008288 http://www.dafinet.dk/DAFINET/Home_files/DAFINET%20November%206-7%202012%20Abstractbook.pdf eng eng University of Copenhagen info:eu-repo/semantics/restrictedAccess Schönherz , A A , Lorenzen , N & Einer-Jensen , K 2012 , Inter-Species Transmission of Viral Haemorrhagic Septicaemia Virus Between Turbot (Scophthalmus Maximus) and Rainbow Trout (Onchorhynchus Mykiss) . in DAFINET Workshop : Immune Responses in Fish : Book of abstracts . University of Copenhagen , pp. 24 , DAFINET Workshop : Immune Responses in Fish , Copenhagen , Denmark , 06/11/2012 . < http://www.dafinet.dk/DAFINET/Home_files/DAFINET%20November%206-7%202012%20Abstractbook.pdf > /dk/atira/pure/sustainabledevelopmentgoals/life_below_water SDG 14 - Life Below Water conferenceObject 2012 ftdtupubl 2022-08-14T08:13:27Z Viral haemorrhagic septicaemia is a serious viral disease of teleost fish with high economic impact on the aquaculture industry. The disease is caused by the viral haemorrhagic septicaemia virus (VHSV), an RNA virus belonging to the family Rhabdoviridae. Compared to other rhabdoviruses infecting fish, VHSV has an exceptional wide host range of more than 70 species across marine and aquatic environments. To establish such a wide host range host-specific adaptation would be disadvantageous, nevertheless, host-specific differences in pathogenicity have been observed for VHSV. The divergence in pathogenicity, however, is not fully resembled in the phylogeny, which indicates a correlation between geographic regions rather than host species. The objective of this study was to identify whether VHSV has the ability to transmit between different host species or whether viral transmission is restricedt to one host species through host-specific adaptation. To investigate the existence of inter-species transmission and host-specificity a cohabitation challenge between turbot and rainbow trout was conducted with turbot as donor- and rainbow trout as recipient host species. Turbot were ip challenged with a turbot- or a rainbow trout adapted VHSV isolate and subsequently grouped with naïve rainbow trout. Mortality and viral shed was monitored daily. Both virus isolates showed signs of host-specific adaptation based on differences in replication dynamics, viral production, and virulence. Host-specific adaptation, however, did not result in total restriction of inter-species transmission. Despite of host-specific adaptation, the rainbow trout adapted VHSV isolate was able to cause disease in turbot resulting in subsequent infection of cohabiting rainbow trout, thus indicating the existence of inter-species transmission of VHSV between turbot and rainbow trout. Conference Object Scophthalmus maximus Turbot Technical University of Denmark: DTU Orbit |
institution |
Open Polar |
collection |
Technical University of Denmark: DTU Orbit |
op_collection_id |
ftdtupubl |
language |
English |
topic |
/dk/atira/pure/sustainabledevelopmentgoals/life_below_water SDG 14 - Life Below Water |
spellingShingle |
/dk/atira/pure/sustainabledevelopmentgoals/life_below_water SDG 14 - Life Below Water Schönherz, A. A. Lorenzen, Niels Einer-Jensen, Katja Inter-Species Transmission of Viral Haemorrhagic Septicaemia Virus Between Turbot (Scophthalmus Maximus) and Rainbow Trout (Onchorhynchus Mykiss) |
topic_facet |
/dk/atira/pure/sustainabledevelopmentgoals/life_below_water SDG 14 - Life Below Water |
description |
Viral haemorrhagic septicaemia is a serious viral disease of teleost fish with high economic impact on the aquaculture industry. The disease is caused by the viral haemorrhagic septicaemia virus (VHSV), an RNA virus belonging to the family Rhabdoviridae. Compared to other rhabdoviruses infecting fish, VHSV has an exceptional wide host range of more than 70 species across marine and aquatic environments. To establish such a wide host range host-specific adaptation would be disadvantageous, nevertheless, host-specific differences in pathogenicity have been observed for VHSV. The divergence in pathogenicity, however, is not fully resembled in the phylogeny, which indicates a correlation between geographic regions rather than host species. The objective of this study was to identify whether VHSV has the ability to transmit between different host species or whether viral transmission is restricedt to one host species through host-specific adaptation. To investigate the existence of inter-species transmission and host-specificity a cohabitation challenge between turbot and rainbow trout was conducted with turbot as donor- and rainbow trout as recipient host species. Turbot were ip challenged with a turbot- or a rainbow trout adapted VHSV isolate and subsequently grouped with naïve rainbow trout. Mortality and viral shed was monitored daily. Both virus isolates showed signs of host-specific adaptation based on differences in replication dynamics, viral production, and virulence. Host-specific adaptation, however, did not result in total restriction of inter-species transmission. Despite of host-specific adaptation, the rainbow trout adapted VHSV isolate was able to cause disease in turbot resulting in subsequent infection of cohabiting rainbow trout, thus indicating the existence of inter-species transmission of VHSV between turbot and rainbow trout. |
format |
Conference Object |
author |
Schönherz, A. A. Lorenzen, Niels Einer-Jensen, Katja |
author_facet |
Schönherz, A. A. Lorenzen, Niels Einer-Jensen, Katja |
author_sort |
Schönherz, A. A. |
title |
Inter-Species Transmission of Viral Haemorrhagic Septicaemia Virus Between Turbot (Scophthalmus Maximus) and Rainbow Trout (Onchorhynchus Mykiss) |
title_short |
Inter-Species Transmission of Viral Haemorrhagic Septicaemia Virus Between Turbot (Scophthalmus Maximus) and Rainbow Trout (Onchorhynchus Mykiss) |
title_full |
Inter-Species Transmission of Viral Haemorrhagic Septicaemia Virus Between Turbot (Scophthalmus Maximus) and Rainbow Trout (Onchorhynchus Mykiss) |
title_fullStr |
Inter-Species Transmission of Viral Haemorrhagic Septicaemia Virus Between Turbot (Scophthalmus Maximus) and Rainbow Trout (Onchorhynchus Mykiss) |
title_full_unstemmed |
Inter-Species Transmission of Viral Haemorrhagic Septicaemia Virus Between Turbot (Scophthalmus Maximus) and Rainbow Trout (Onchorhynchus Mykiss) |
title_sort |
inter-species transmission of viral haemorrhagic septicaemia virus between turbot (scophthalmus maximus) and rainbow trout (onchorhynchus mykiss) |
publisher |
University of Copenhagen |
publishDate |
2012 |
url |
https://orbit.dtu.dk/en/publications/e15b51a5-df97-42e4-a296-fb6339008288 http://www.dafinet.dk/DAFINET/Home_files/DAFINET%20November%206-7%202012%20Abstractbook.pdf |
genre |
Scophthalmus maximus Turbot |
genre_facet |
Scophthalmus maximus Turbot |
op_source |
Schönherz , A A , Lorenzen , N & Einer-Jensen , K 2012 , Inter-Species Transmission of Viral Haemorrhagic Septicaemia Virus Between Turbot (Scophthalmus Maximus) and Rainbow Trout (Onchorhynchus Mykiss) . in DAFINET Workshop : Immune Responses in Fish : Book of abstracts . University of Copenhagen , pp. 24 , DAFINET Workshop : Immune Responses in Fish , Copenhagen , Denmark , 06/11/2012 . < http://www.dafinet.dk/DAFINET/Home_files/DAFINET%20November%206-7%202012%20Abstractbook.pdf > |
op_rights |
info:eu-repo/semantics/restrictedAccess |
_version_ |
1766189106689212416 |