POISONINGS FROM FLESH OF THE GREENLAND SHARK SOMNIOSUS MICROCEPHALUS MAY BE DUE TO TRIMETHYLAMINE

Poisonings from flesh of the Greenland shark Somniosus microcephalus may be due to trimethylamine. Toxicon 29 , 1205-1212, 1991 .-The flesh of the Greenland shark, S omniosus microcephalus , especially in fresh condition, is toxic to both dog and man. Analysis of the toxic fractions indicates the pr...

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Main Authors: Anthoni, Uffe, Christophersen, Carsten, Gram, Lone, Nielsen, Niels H., Nielsen, Per
Format: Article in Journal/Newspaper
Language:English
Published: 1991
Subjects:
Greenland
Somniosus microcephalus
Online Access:https://orbit.dtu.dk/en/publications/97c56b7d-7f46-4188-800a-d85ccf6b8ac1
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spelling ftdtupubl:oai:pure.atira.dk:publications/97c56b7d-7f46-4188-800a-d85ccf6b8ac1 2024-05-19T07:41:03+00:00 POISONINGS FROM FLESH OF THE GREENLAND SHARK SOMNIOSUS MICROCEPHALUS MAY BE DUE TO TRIMETHYLAMINE Anthoni, Uffe Christophersen, Carsten Gram, Lone Nielsen, Niels H. Nielsen, Per 1991 https://orbit.dtu.dk/en/publications/97c56b7d-7f46-4188-800a-d85ccf6b8ac1 eng eng https://orbit.dtu.dk/en/publications/97c56b7d-7f46-4188-800a-d85ccf6b8ac1 info:eu-repo/semantics/closedAccess Anthoni , U , Christophersen , C , Gram , L , Nielsen , N H & Nielsen , P 1991 , ' POISONINGS FROM FLESH OF THE GREENLAND SHARK SOMNIOSUS MICROCEPHALUS MAY BE DUE TO TRIMETHYLAMINE ' , Toxicon , vol. 29 , no. 10 , pp. 1205-1212 . article 1991 ftdtupubl 2024-05-01T00:35:54Z Poisonings from flesh of the Greenland shark Somniosus microcephalus may be due to trimethylamine. Toxicon 29 , 1205-1212, 1991 .-The flesh of the Greenland shark, S omniosus microcephalus , especially in fresh condition, is toxic to both dog and man. Analysis of the toxic fractions indicates the presence of large amounts of trimethylamine oxide (TMAO) but no other substances that could be directly responsible for the poisoning. The symptoms appear to be due to an acute trimethylamine (TMA) poisoning arising from intestinal reduction of TMAO to TMA. TMA stimulates contraction of the guinea-pig ileum (antagonized by atropine but not hexamethonium). Low concentrations of TMA increase contraction of the rat phrenic nerve-diaphragm preparation, whereas higher concentrations cause blockade Article in Journal/Newspaper Greenland Somniosus microcephalus Technical University of Denmark: DTU Orbit
institution Open Polar
collection Technical University of Denmark: DTU Orbit
op_collection_id ftdtupubl
language English
description Poisonings from flesh of the Greenland shark Somniosus microcephalus may be due to trimethylamine. Toxicon 29 , 1205-1212, 1991 .-The flesh of the Greenland shark, S omniosus microcephalus , especially in fresh condition, is toxic to both dog and man. Analysis of the toxic fractions indicates the presence of large amounts of trimethylamine oxide (TMAO) but no other substances that could be directly responsible for the poisoning. The symptoms appear to be due to an acute trimethylamine (TMA) poisoning arising from intestinal reduction of TMAO to TMA. TMA stimulates contraction of the guinea-pig ileum (antagonized by atropine but not hexamethonium). Low concentrations of TMA increase contraction of the rat phrenic nerve-diaphragm preparation, whereas higher concentrations cause blockade
format Article in Journal/Newspaper
author Anthoni, Uffe
Christophersen, Carsten
Gram, Lone
Nielsen, Niels H.
Nielsen, Per
spellingShingle Anthoni, Uffe
Christophersen, Carsten
Gram, Lone
Nielsen, Niels H.
Nielsen, Per
POISONINGS FROM FLESH OF THE GREENLAND SHARK SOMNIOSUS MICROCEPHALUS MAY BE DUE TO TRIMETHYLAMINE
author_facet Anthoni, Uffe
Christophersen, Carsten
Gram, Lone
Nielsen, Niels H.
Nielsen, Per
author_sort Anthoni, Uffe
title POISONINGS FROM FLESH OF THE GREENLAND SHARK SOMNIOSUS MICROCEPHALUS MAY BE DUE TO TRIMETHYLAMINE
title_short POISONINGS FROM FLESH OF THE GREENLAND SHARK SOMNIOSUS MICROCEPHALUS MAY BE DUE TO TRIMETHYLAMINE
title_full POISONINGS FROM FLESH OF THE GREENLAND SHARK SOMNIOSUS MICROCEPHALUS MAY BE DUE TO TRIMETHYLAMINE
title_fullStr POISONINGS FROM FLESH OF THE GREENLAND SHARK SOMNIOSUS MICROCEPHALUS MAY BE DUE TO TRIMETHYLAMINE
title_full_unstemmed POISONINGS FROM FLESH OF THE GREENLAND SHARK SOMNIOSUS MICROCEPHALUS MAY BE DUE TO TRIMETHYLAMINE
title_sort poisonings from flesh of the greenland shark somniosus microcephalus may be due to trimethylamine
publishDate 1991
url https://orbit.dtu.dk/en/publications/97c56b7d-7f46-4188-800a-d85ccf6b8ac1
genre Greenland
Somniosus microcephalus
genre_facet Greenland
Somniosus microcephalus
op_source Anthoni , U , Christophersen , C , Gram , L , Nielsen , N H & Nielsen , P 1991 , ' POISONINGS FROM FLESH OF THE GREENLAND SHARK SOMNIOSUS MICROCEPHALUS MAY BE DUE TO TRIMETHYLAMINE ' , Toxicon , vol. 29 , no. 10 , pp. 1205-1212 .
op_relation https://orbit.dtu.dk/en/publications/97c56b7d-7f46-4188-800a-d85ccf6b8ac1
op_rights info:eu-repo/semantics/closedAccess
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