Mixed function oxidase dependent biotransformation of polychlorinated biphenyls by different species of fish from the North Sea
Mixed function oxidase (MFO) dependent biotransformation of polychlorinated biphenyls (PCBs) was measured in three different fish species from the North Sea. Liver microsomes of plaice (Pleuronectes platessa), dab (Limanda limanda) and cod (Gadus morhua) were isolated and incubated with different PC...
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Language: | English |
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ftdtupubl:oai:pure.atira.dk:publications/69b3f6a2-0b1f-4fee-b3fd-7a53c61a582c 2023-05-15T16:19:03+02:00 Mixed function oxidase dependent biotransformation of polychlorinated biphenyls by different species of fish from the North Sea Mehrtens, G. Laturnus, F. 1999 https://orbit.dtu.dk/en/publications/69b3f6a2-0b1f-4fee-b3fd-7a53c61a582c https://doi.org/10.1016/S0045-6535(98)00501-3 eng eng info:eu-repo/semantics/restrictedAccess Mehrtens , G & Laturnus , F 1999 , ' Mixed function oxidase dependent biotransformation of polychlorinated biphenyls by different species of fish from the North Sea ' , Chemosphere , vol. 38 , no. 13 , pp. 2995-3002 . https://doi.org/10.1016/S0045-6535(98)00501-3 Planteproduktion og stofomsætning article 1999 ftdtupubl https://doi.org/10.1016/S0045-6535(98)00501-3 2023-01-12T00:02:55Z Mixed function oxidase (MFO) dependent biotransformation of polychlorinated biphenyls (PCBs) was measured in three different fish species from the North Sea. Liver microsomes of plaice (Pleuronectes platessa), dab (Limanda limanda) and cod (Gadus morhua) were isolated and incubated with different PCB congeners. Metabolites of PCBs were identified as monohydroxylated PCBs. Hydroxylation took place in meta- or para-position of the PCB molecules, preferential in para-position. Metabolization and metabolic rates depended on the substitution pattern of PCBs and the degree of chlorination. Biotransformations were also species dependent. The flatfish dab and plaice exhibited higher metabolic rates than cod (C) 1999 Elsevier Science Ltd. All rights reserved. Article in Journal/Newspaper Gadus morhua Technical University of Denmark: DTU Orbit Chemosphere 38 13 2995 3002 |
institution |
Open Polar |
collection |
Technical University of Denmark: DTU Orbit |
op_collection_id |
ftdtupubl |
language |
English |
topic |
Planteproduktion og stofomsætning |
spellingShingle |
Planteproduktion og stofomsætning Mehrtens, G. Laturnus, F. Mixed function oxidase dependent biotransformation of polychlorinated biphenyls by different species of fish from the North Sea |
topic_facet |
Planteproduktion og stofomsætning |
description |
Mixed function oxidase (MFO) dependent biotransformation of polychlorinated biphenyls (PCBs) was measured in three different fish species from the North Sea. Liver microsomes of plaice (Pleuronectes platessa), dab (Limanda limanda) and cod (Gadus morhua) were isolated and incubated with different PCB congeners. Metabolites of PCBs were identified as monohydroxylated PCBs. Hydroxylation took place in meta- or para-position of the PCB molecules, preferential in para-position. Metabolization and metabolic rates depended on the substitution pattern of PCBs and the degree of chlorination. Biotransformations were also species dependent. The flatfish dab and plaice exhibited higher metabolic rates than cod (C) 1999 Elsevier Science Ltd. All rights reserved. |
format |
Article in Journal/Newspaper |
author |
Mehrtens, G. Laturnus, F. |
author_facet |
Mehrtens, G. Laturnus, F. |
author_sort |
Mehrtens, G. |
title |
Mixed function oxidase dependent biotransformation of polychlorinated biphenyls by different species of fish from the North Sea |
title_short |
Mixed function oxidase dependent biotransformation of polychlorinated biphenyls by different species of fish from the North Sea |
title_full |
Mixed function oxidase dependent biotransformation of polychlorinated biphenyls by different species of fish from the North Sea |
title_fullStr |
Mixed function oxidase dependent biotransformation of polychlorinated biphenyls by different species of fish from the North Sea |
title_full_unstemmed |
Mixed function oxidase dependent biotransformation of polychlorinated biphenyls by different species of fish from the North Sea |
title_sort |
mixed function oxidase dependent biotransformation of polychlorinated biphenyls by different species of fish from the north sea |
publishDate |
1999 |
url |
https://orbit.dtu.dk/en/publications/69b3f6a2-0b1f-4fee-b3fd-7a53c61a582c https://doi.org/10.1016/S0045-6535(98)00501-3 |
genre |
Gadus morhua |
genre_facet |
Gadus morhua |
op_source |
Mehrtens , G & Laturnus , F 1999 , ' Mixed function oxidase dependent biotransformation of polychlorinated biphenyls by different species of fish from the North Sea ' , Chemosphere , vol. 38 , no. 13 , pp. 2995-3002 . https://doi.org/10.1016/S0045-6535(98)00501-3 |
op_rights |
info:eu-repo/semantics/restrictedAccess |
op_doi |
https://doi.org/10.1016/S0045-6535(98)00501-3 |
container_title |
Chemosphere |
container_volume |
38 |
container_issue |
13 |
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2995 |
op_container_end_page |
3002 |
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1766005366917693440 |