Genetic population structure of marine viral haemorrhagic septicaemia virus (VHSV)
The nucleotide sequences of a specific region of the nucleoprotein gene were compared in order to investigate the genetic population structure of marine viral haemorrhagic septicaemia virus (VHSV). Analysis of the sequence from 128 isolates of diverse geographic and host origin renders this the most...
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ftdtupubl:oai:pure.atira.dk:publications/0d2cbf07-9321-431f-a6df-683e825f2fce 2024-09-09T20:12:33+00:00 Genetic population structure of marine viral haemorrhagic septicaemia virus (VHSV) Snow, M. Bain, N. Black, J. Taupin, V. Cunningham, C.O. King, J.A. Skall, Helle Frank Raynard, R.S. 2004 https://orbit.dtu.dk/en/publications/0d2cbf07-9321-431f-a6df-683e825f2fce eng eng https://orbit.dtu.dk/en/publications/0d2cbf07-9321-431f-a6df-683e825f2fce info:eu-repo/semantics/restrictedAccess Snow , M , Bain , N , Black , J , Taupin , V , Cunningham , C O , King , J A , Skall , H F & Raynard , R S 2004 , ' Genetic population structure of marine viral haemorrhagic septicaemia virus (VHSV) ' , Diseases of Aquatic Organisms , vol. 61 , no. 1-2 , pp. 11-21 . viral haemorrhagic septicaemia virus VHSV nucleoprotein phylogenetics VHS /dk/atira/pure/sustainabledevelopmentgoals/life_below_water name=SDG 14 - Life Below Water article 2004 ftdtupubl 2024-06-18T14:27:34Z The nucleotide sequences of a specific region of the nucleoprotein gene were compared in order to investigate the genetic population structure of marine viral haemorrhagic septicaemia virus (VHSV). Analysis of the sequence from 128 isolates of diverse geographic and host origin renders this the most comprehensive molecular epidemiological study of marine VHSV conducted to date. Phylogenetic analysis of nucleoprotein gene sequences confirmed the existence of the 4 major genotypes previously identified based on N- and subsequent G-gene based analyses. The range of Genotype I included subgroups of isolates associated with rainbow trout aquaculture (Genotype la) and those from the Baltic marine environment (Genotype Ib) to emphasise the relatively close genetic relationship between these isolates. The existence of an additional genotype circulating within the Baltic Sea (Genotype II) was also confirmed. Genotype III included marine isolates from around the British Isles in addition to those associated with turbot mariculture, highlighting a continued risk to the development of this industry. Genotype IV consisted of isolates from the marine environment in North America. Taken together, these findings suggest a marine origin of VHSV in rainbow trout aquaculture. The implications of these findings with respect to the future control of VHSV are discussed. The capacity for molecular phylogenetic analysis to resolve complex epidemiological problems is also demonstrated and its likely future importance to disease management issues highlighted. Article in Journal/Newspaper Turbot Technical University of Denmark: DTU Orbit |
institution |
Open Polar |
collection |
Technical University of Denmark: DTU Orbit |
op_collection_id |
ftdtupubl |
language |
English |
topic |
viral haemorrhagic septicaemia virus VHSV nucleoprotein phylogenetics VHS /dk/atira/pure/sustainabledevelopmentgoals/life_below_water name=SDG 14 - Life Below Water |
spellingShingle |
viral haemorrhagic septicaemia virus VHSV nucleoprotein phylogenetics VHS /dk/atira/pure/sustainabledevelopmentgoals/life_below_water name=SDG 14 - Life Below Water Snow, M. Bain, N. Black, J. Taupin, V. Cunningham, C.O. King, J.A. Skall, Helle Frank Raynard, R.S. Genetic population structure of marine viral haemorrhagic septicaemia virus (VHSV) |
topic_facet |
viral haemorrhagic septicaemia virus VHSV nucleoprotein phylogenetics VHS /dk/atira/pure/sustainabledevelopmentgoals/life_below_water name=SDG 14 - Life Below Water |
description |
The nucleotide sequences of a specific region of the nucleoprotein gene were compared in order to investigate the genetic population structure of marine viral haemorrhagic septicaemia virus (VHSV). Analysis of the sequence from 128 isolates of diverse geographic and host origin renders this the most comprehensive molecular epidemiological study of marine VHSV conducted to date. Phylogenetic analysis of nucleoprotein gene sequences confirmed the existence of the 4 major genotypes previously identified based on N- and subsequent G-gene based analyses. The range of Genotype I included subgroups of isolates associated with rainbow trout aquaculture (Genotype la) and those from the Baltic marine environment (Genotype Ib) to emphasise the relatively close genetic relationship between these isolates. The existence of an additional genotype circulating within the Baltic Sea (Genotype II) was also confirmed. Genotype III included marine isolates from around the British Isles in addition to those associated with turbot mariculture, highlighting a continued risk to the development of this industry. Genotype IV consisted of isolates from the marine environment in North America. Taken together, these findings suggest a marine origin of VHSV in rainbow trout aquaculture. The implications of these findings with respect to the future control of VHSV are discussed. The capacity for molecular phylogenetic analysis to resolve complex epidemiological problems is also demonstrated and its likely future importance to disease management issues highlighted. |
format |
Article in Journal/Newspaper |
author |
Snow, M. Bain, N. Black, J. Taupin, V. Cunningham, C.O. King, J.A. Skall, Helle Frank Raynard, R.S. |
author_facet |
Snow, M. Bain, N. Black, J. Taupin, V. Cunningham, C.O. King, J.A. Skall, Helle Frank Raynard, R.S. |
author_sort |
Snow, M. |
title |
Genetic population structure of marine viral haemorrhagic septicaemia virus (VHSV) |
title_short |
Genetic population structure of marine viral haemorrhagic septicaemia virus (VHSV) |
title_full |
Genetic population structure of marine viral haemorrhagic septicaemia virus (VHSV) |
title_fullStr |
Genetic population structure of marine viral haemorrhagic septicaemia virus (VHSV) |
title_full_unstemmed |
Genetic population structure of marine viral haemorrhagic septicaemia virus (VHSV) |
title_sort |
genetic population structure of marine viral haemorrhagic septicaemia virus (vhsv) |
publishDate |
2004 |
url |
https://orbit.dtu.dk/en/publications/0d2cbf07-9321-431f-a6df-683e825f2fce |
genre |
Turbot |
genre_facet |
Turbot |
op_source |
Snow , M , Bain , N , Black , J , Taupin , V , Cunningham , C O , King , J A , Skall , H F & Raynard , R S 2004 , ' Genetic population structure of marine viral haemorrhagic septicaemia virus (VHSV) ' , Diseases of Aquatic Organisms , vol. 61 , no. 1-2 , pp. 11-21 . |
op_relation |
https://orbit.dtu.dk/en/publications/0d2cbf07-9321-431f-a6df-683e825f2fce |
op_rights |
info:eu-repo/semantics/restrictedAccess |
_version_ |
1809947136055312384 |