Human Infection with Rickettsia honei, Thailand
The original Thai tick typhus isolate, TT-118, was obtained from a mixed pool of Ixodes sp. and Rhipicephalus sp. larval ticks from Rattus rattus trapped in Chiangmai Province, Thailand, in 1962 (1) and has recently been determined to be a strain of Rickettsia honei, the etiologic agent of Flinders...
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ftdtic:ADA469012 2023-05-15T18:05:31+02:00 Human Infection with Rickettsia honei, Thailand Jiang, Ju Sangkasuwan, Vichai Lerdthusnee, Kriangkrai Sukwit, Suchitra Chuenchitra, Tippawan Rozmajzl, Patrick J. Eamsila, Chirapa Jones, James W. Richards, Allen L. NAVAL MEDICAL RESEARCH CENTER SILVER SPRING MD 2005-09 text/html http://www.dtic.mil/docs/citations/ADA469012 http://oai.dtic.mil/oai/oai?&verb=getRecord&metadataPrefix=html&identifier=ADA469012 en eng http://www.dtic.mil/docs/citations/ADA469012 Approved for public release; distribution is unlimited. DTIC Medicine and Medical Research Microbiology *INFECTIOUS DISEASES *RICKETTSIA REPRINTS SIGNS AND SYMPTOMS ANTIGENS TYPHUS THAILAND ISLANDS TICKS ETIOLOGY TT-118 SFG(SPOTTED FEVER GROUP) RICKETTSIA HONEI Text 2005 ftdtic 2016-02-22T10:09:40Z The original Thai tick typhus isolate, TT-118, was obtained from a mixed pool of Ixodes sp. and Rhipicephalus sp. larval ticks from Rattus rattus trapped in Chiangmai Province, Thailand, in 1962 (1) and has recently been determined to be a strain of Rickettsia honei, the etiologic agent of Flinders Island spotted fever (2). No isolate has been associated with Thai tick typhus in humans, and TT-118 was found only to be moderately pathogenic for guinea pigs and gerbils (1). However, evidence of spotted fever rickettsiosis has been seen in Thailand; this evidence comes from 2 reports of a total of 11 cases, 3 cases from Chiangmai and 8 cases from the Thailand-Burma border. All 11 patients had signs and symptoms characteristic of spotted fever rickettsiosis, and their sera were reactive to spotted fever group (SFG) rickettsial antigens, including those derived from TT-118 (3,4). Additional proof of the presence of spotted fever rickettsiae in Thailand derives from rodent (5) and human (6,7) serosurveys. In addition, spotted fever agents have been demonstrated in Thai ticks by using molecular biology techniques to detect rickettsiae (8 10). Collectively, these reports indicate that SFG rickettsiae and rickettsioses exist within Thailand. However, at the time of this writing, detection of an SFG rickettsia from a human source had not been reported in Thailand. Pub. in Jnl. of Emerging Infrectious Diseases, v11 n9 p1473-1475, September 2005. Text Rattus rattus Defense Technical Information Center: DTIC Technical Reports database Flinders ENVELOPE(-66.667,-66.667,-69.267,-69.267) |
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Defense Technical Information Center: DTIC Technical Reports database |
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ftdtic |
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English |
topic |
Medicine and Medical Research Microbiology *INFECTIOUS DISEASES *RICKETTSIA REPRINTS SIGNS AND SYMPTOMS ANTIGENS TYPHUS THAILAND ISLANDS TICKS ETIOLOGY TT-118 SFG(SPOTTED FEVER GROUP) RICKETTSIA HONEI |
spellingShingle |
Medicine and Medical Research Microbiology *INFECTIOUS DISEASES *RICKETTSIA REPRINTS SIGNS AND SYMPTOMS ANTIGENS TYPHUS THAILAND ISLANDS TICKS ETIOLOGY TT-118 SFG(SPOTTED FEVER GROUP) RICKETTSIA HONEI Jiang, Ju Sangkasuwan, Vichai Lerdthusnee, Kriangkrai Sukwit, Suchitra Chuenchitra, Tippawan Rozmajzl, Patrick J. Eamsila, Chirapa Jones, James W. Richards, Allen L. Human Infection with Rickettsia honei, Thailand |
topic_facet |
Medicine and Medical Research Microbiology *INFECTIOUS DISEASES *RICKETTSIA REPRINTS SIGNS AND SYMPTOMS ANTIGENS TYPHUS THAILAND ISLANDS TICKS ETIOLOGY TT-118 SFG(SPOTTED FEVER GROUP) RICKETTSIA HONEI |
description |
The original Thai tick typhus isolate, TT-118, was obtained from a mixed pool of Ixodes sp. and Rhipicephalus sp. larval ticks from Rattus rattus trapped in Chiangmai Province, Thailand, in 1962 (1) and has recently been determined to be a strain of Rickettsia honei, the etiologic agent of Flinders Island spotted fever (2). No isolate has been associated with Thai tick typhus in humans, and TT-118 was found only to be moderately pathogenic for guinea pigs and gerbils (1). However, evidence of spotted fever rickettsiosis has been seen in Thailand; this evidence comes from 2 reports of a total of 11 cases, 3 cases from Chiangmai and 8 cases from the Thailand-Burma border. All 11 patients had signs and symptoms characteristic of spotted fever rickettsiosis, and their sera were reactive to spotted fever group (SFG) rickettsial antigens, including those derived from TT-118 (3,4). Additional proof of the presence of spotted fever rickettsiae in Thailand derives from rodent (5) and human (6,7) serosurveys. In addition, spotted fever agents have been demonstrated in Thai ticks by using molecular biology techniques to detect rickettsiae (8 10). Collectively, these reports indicate that SFG rickettsiae and rickettsioses exist within Thailand. However, at the time of this writing, detection of an SFG rickettsia from a human source had not been reported in Thailand. Pub. in Jnl. of Emerging Infrectious Diseases, v11 n9 p1473-1475, September 2005. |
author2 |
NAVAL MEDICAL RESEARCH CENTER SILVER SPRING MD |
format |
Text |
author |
Jiang, Ju Sangkasuwan, Vichai Lerdthusnee, Kriangkrai Sukwit, Suchitra Chuenchitra, Tippawan Rozmajzl, Patrick J. Eamsila, Chirapa Jones, James W. Richards, Allen L. |
author_facet |
Jiang, Ju Sangkasuwan, Vichai Lerdthusnee, Kriangkrai Sukwit, Suchitra Chuenchitra, Tippawan Rozmajzl, Patrick J. Eamsila, Chirapa Jones, James W. Richards, Allen L. |
author_sort |
Jiang, Ju |
title |
Human Infection with Rickettsia honei, Thailand |
title_short |
Human Infection with Rickettsia honei, Thailand |
title_full |
Human Infection with Rickettsia honei, Thailand |
title_fullStr |
Human Infection with Rickettsia honei, Thailand |
title_full_unstemmed |
Human Infection with Rickettsia honei, Thailand |
title_sort |
human infection with rickettsia honei, thailand |
publishDate |
2005 |
url |
http://www.dtic.mil/docs/citations/ADA469012 http://oai.dtic.mil/oai/oai?&verb=getRecord&metadataPrefix=html&identifier=ADA469012 |
long_lat |
ENVELOPE(-66.667,-66.667,-69.267,-69.267) |
geographic |
Flinders |
geographic_facet |
Flinders |
genre |
Rattus rattus |
genre_facet |
Rattus rattus |
op_source |
DTIC |
op_relation |
http://www.dtic.mil/docs/citations/ADA469012 |
op_rights |
Approved for public release; distribution is unlimited. |
_version_ |
1766176993281310720 |