Data from: Partial genomic survival of cave bears in living brown bears
Although many large mammal species went extinct at the end of the Pleistocene epoch, their DNA may persist due to past episodes of interspecies admixture. However, direct empirical evidence of the persistence of ancient alleles remains scarce. Here, we present multifold coverage genomic data from fo...
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ftdryad:oai:v1.datadryad.org:10255/dryad.186280 2023-05-15T18:42:03+02:00 Data from: Partial genomic survival of cave bears in living brown bears Barlow, Axel Cahill, James A. Hartmann, Stefanie Theunert, Christoph Xenikoudakis, Georgios Fortes, Gloria G. Paijmans, Johanna L. A. Rabeder, Gernot Frischauf, Christine Grandal-d'Anglade, Aurora García-Vázquez, Ana Murtskhvaladze, Marine Saarma, Urmas Anijalg, Peeter Skrbinšek, Tomaž Bertorelle, Giorgio Gasparian, Boris Bar-Oz, Guy Pinhasi, Ron Slatkin, Montgomery Dalén, Love Shapiro, Beth Hofreiter, Michael Late Pleistocene Holocene 2018-09-26T17:36:45Z http://hdl.handle.net/10255/dryad.186280 https://doi.org/10.5061/dryad.cr1496b unknown doi:10.5061/dryad.cr1496b/1 doi:10.5061/dryad.cr1496b/2 doi:10.5061/dryad.cr1496b/3 doi:10.5061/dryad.cr1496b/4 doi:10.5061/dryad.cr1496b/5 doi:10.5061/dryad.cr1496b/6 doi:10.5061/dryad.cr1496b/7 doi:10.5061/dryad.cr1496b/8 doi:10.5061/dryad.cr1496b/9 doi:10.5061/dryad.cr1496b/10 doi:10.5061/dryad.cr1496b/11 doi:10.5061/dryad.cr1496b/12 doi:10.5061/dryad.cr1496b/13 doi:10.5061/dryad.cr1496b/14 doi:10.5061/dryad.cr1496b/15 doi:10.5061/dryad.cr1496b/16 doi:10.5061/dryad.cr1496b/17 doi:10.5061/dryad.cr1496b/18 doi:10.1038/s41559-018-0654-8 doi:10.5061/dryad.cr1496b Barlow A, Cahill JA, Hartmann S, Theunert C, Xenikoudakis G, Fortes GG, Paijmans JLA, Rabeder G, Frischauf C, Grandal-d'Anglade A, García-Vázquez A, Murtskhvaladze M, Saarma U, Anijalg P, Skrbinšek T, Bertorelle G, Gasparian B, Bar-Oz G, Pinhasi R, Slatkin M, Dalén L, Shapiro B, Hofreiter M (2018) Partial genomic survival of cave bears in living brown bears. Nature Ecology & Evolution 2: 1563–1570. http://hdl.handle.net/10255/dryad.186280 haploidised fasta sequences Article 2018 ftdryad https://doi.org/10.5061/dryad.cr1496b https://doi.org/10.5061/dryad.cr1496b/1 https://doi.org/10.5061/dryad.cr1496b/2 https://doi.org/10.5061/dryad.cr1496b/3 https://doi.org/10.5061/dryad.cr1496b/4 https://doi.org/10.5061/dryad.cr1496b/5 https 2020-01-01T16:12:35Z Although many large mammal species went extinct at the end of the Pleistocene epoch, their DNA may persist due to past episodes of interspecies admixture. However, direct empirical evidence of the persistence of ancient alleles remains scarce. Here, we present multifold coverage genomic data from four Late Pleistocene cave bears (Ursus spelaeus complex) and show that cave bears hybridized with brown bears (Ursus arctos) during the Pleistocene. We develop an approach to assess both the directionality and relative timing of gene flow. We find that segments of cave bear DNA still persist in the genomes of living brown bears, with cave bears contributing 0.9 to 2.4% of the genomes of all brown bears investigated. Our results show that even though extinction is typically considered as absolute, following admixture, fragments of the gene pool of extinct species can survive for tens of thousands of years in the genomes of extant recipient species. Article in Journal/Newspaper Ursus arctos Dryad Digital Repository (Duke University) |
institution |
Open Polar |
collection |
Dryad Digital Repository (Duke University) |
op_collection_id |
ftdryad |
language |
unknown |
topic |
haploidised fasta sequences |
spellingShingle |
haploidised fasta sequences Barlow, Axel Cahill, James A. Hartmann, Stefanie Theunert, Christoph Xenikoudakis, Georgios Fortes, Gloria G. Paijmans, Johanna L. A. Rabeder, Gernot Frischauf, Christine Grandal-d'Anglade, Aurora García-Vázquez, Ana Murtskhvaladze, Marine Saarma, Urmas Anijalg, Peeter Skrbinšek, Tomaž Bertorelle, Giorgio Gasparian, Boris Bar-Oz, Guy Pinhasi, Ron Slatkin, Montgomery Dalén, Love Shapiro, Beth Hofreiter, Michael Data from: Partial genomic survival of cave bears in living brown bears |
topic_facet |
haploidised fasta sequences |
description |
Although many large mammal species went extinct at the end of the Pleistocene epoch, their DNA may persist due to past episodes of interspecies admixture. However, direct empirical evidence of the persistence of ancient alleles remains scarce. Here, we present multifold coverage genomic data from four Late Pleistocene cave bears (Ursus spelaeus complex) and show that cave bears hybridized with brown bears (Ursus arctos) during the Pleistocene. We develop an approach to assess both the directionality and relative timing of gene flow. We find that segments of cave bear DNA still persist in the genomes of living brown bears, with cave bears contributing 0.9 to 2.4% of the genomes of all brown bears investigated. Our results show that even though extinction is typically considered as absolute, following admixture, fragments of the gene pool of extinct species can survive for tens of thousands of years in the genomes of extant recipient species. |
format |
Article in Journal/Newspaper |
author |
Barlow, Axel Cahill, James A. Hartmann, Stefanie Theunert, Christoph Xenikoudakis, Georgios Fortes, Gloria G. Paijmans, Johanna L. A. Rabeder, Gernot Frischauf, Christine Grandal-d'Anglade, Aurora García-Vázquez, Ana Murtskhvaladze, Marine Saarma, Urmas Anijalg, Peeter Skrbinšek, Tomaž Bertorelle, Giorgio Gasparian, Boris Bar-Oz, Guy Pinhasi, Ron Slatkin, Montgomery Dalén, Love Shapiro, Beth Hofreiter, Michael |
author_facet |
Barlow, Axel Cahill, James A. Hartmann, Stefanie Theunert, Christoph Xenikoudakis, Georgios Fortes, Gloria G. Paijmans, Johanna L. A. Rabeder, Gernot Frischauf, Christine Grandal-d'Anglade, Aurora García-Vázquez, Ana Murtskhvaladze, Marine Saarma, Urmas Anijalg, Peeter Skrbinšek, Tomaž Bertorelle, Giorgio Gasparian, Boris Bar-Oz, Guy Pinhasi, Ron Slatkin, Montgomery Dalén, Love Shapiro, Beth Hofreiter, Michael |
author_sort |
Barlow, Axel |
title |
Data from: Partial genomic survival of cave bears in living brown bears |
title_short |
Data from: Partial genomic survival of cave bears in living brown bears |
title_full |
Data from: Partial genomic survival of cave bears in living brown bears |
title_fullStr |
Data from: Partial genomic survival of cave bears in living brown bears |
title_full_unstemmed |
Data from: Partial genomic survival of cave bears in living brown bears |
title_sort |
data from: partial genomic survival of cave bears in living brown bears |
publishDate |
2018 |
url |
http://hdl.handle.net/10255/dryad.186280 https://doi.org/10.5061/dryad.cr1496b |
op_coverage |
Late Pleistocene Holocene |
genre |
Ursus arctos |
genre_facet |
Ursus arctos |
op_relation |
doi:10.5061/dryad.cr1496b/1 doi:10.5061/dryad.cr1496b/2 doi:10.5061/dryad.cr1496b/3 doi:10.5061/dryad.cr1496b/4 doi:10.5061/dryad.cr1496b/5 doi:10.5061/dryad.cr1496b/6 doi:10.5061/dryad.cr1496b/7 doi:10.5061/dryad.cr1496b/8 doi:10.5061/dryad.cr1496b/9 doi:10.5061/dryad.cr1496b/10 doi:10.5061/dryad.cr1496b/11 doi:10.5061/dryad.cr1496b/12 doi:10.5061/dryad.cr1496b/13 doi:10.5061/dryad.cr1496b/14 doi:10.5061/dryad.cr1496b/15 doi:10.5061/dryad.cr1496b/16 doi:10.5061/dryad.cr1496b/17 doi:10.5061/dryad.cr1496b/18 doi:10.1038/s41559-018-0654-8 doi:10.5061/dryad.cr1496b Barlow A, Cahill JA, Hartmann S, Theunert C, Xenikoudakis G, Fortes GG, Paijmans JLA, Rabeder G, Frischauf C, Grandal-d'Anglade A, García-Vázquez A, Murtskhvaladze M, Saarma U, Anijalg P, Skrbinšek T, Bertorelle G, Gasparian B, Bar-Oz G, Pinhasi R, Slatkin M, Dalén L, Shapiro B, Hofreiter M (2018) Partial genomic survival of cave bears in living brown bears. Nature Ecology & Evolution 2: 1563–1570. http://hdl.handle.net/10255/dryad.186280 |
op_doi |
https://doi.org/10.5061/dryad.cr1496b https://doi.org/10.5061/dryad.cr1496b/1 https://doi.org/10.5061/dryad.cr1496b/2 https://doi.org/10.5061/dryad.cr1496b/3 https://doi.org/10.5061/dryad.cr1496b/4 https://doi.org/10.5061/dryad.cr1496b/5 https |
_version_ |
1766231654146244608 |