Data from: Telomere elongation during early development is independent of environmental temperatures in Atlantic salmon
There is increasing evidence from endothermic vertebrates that telomeres, which cap the ends of chromosomes and play an important role in chromosome protection, decline in length during postnatal life and are a useful indicator of physiological state and expected lifespan. However, much less is curr...
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ftdryad:oai:v1.datadryad.org:10255/dryad.175559 2023-05-15T15:31:23+02:00 Data from: Telomere elongation during early development is independent of environmental temperatures in Atlantic salmon McLennan, Darryl Armstrong, John D. Stewart, David C. Mckelvey, Simon Boner, Winnie Monaghan, Pat Metcalfe, Neil B. 2018-03-30T13:17:53Z http://hdl.handle.net/10255/dryad.175559 https://doi.org/10.5061/dryad.ct7h4ds unknown doi:10.5061/dryad.ct7h4ds/1 doi:10.1242/jeb.178616 doi:10.5061/dryad.ct7h4ds McLennan D, Armstrong JD, Stewart DC, Mckelvey S, Boner W, Monaghan P, Metcalfe NB (2018) Telomere elongation during early development is independent of environmental temperatures in Atlantic salmon. Journal of Experimental Biology 221(11): jeb178616. http://hdl.handle.net/10255/dryad.175559 cell proliferation environmental effect fish oxidative stress physiology Article 2018 ftdryad https://doi.org/10.5061/dryad.ct7h4ds https://doi.org/10.5061/dryad.ct7h4ds/1 https://doi.org/10.1242/jeb.178616 2020-01-01T16:06:54Z There is increasing evidence from endothermic vertebrates that telomeres, which cap the ends of chromosomes and play an important role in chromosome protection, decline in length during postnatal life and are a useful indicator of physiological state and expected lifespan. However, much less is currently known about telomere dynamics in ectothermic vertebrates, which are likely to differ from that of endotherms, at least in part due to the sensitivity of ectotherm physiology to environmental temperature. We report here on an experiment in which Atlantic salmon were reared through the embryonic and larval stages of development, and under differing temperatures, in order to examine the effects of environmental temperature during early life on telomere dynamics, oxidative DNA damage and cellular proliferation. Telomere length significantly increased between the embryonic and larval stages of development. Contrary to our expectations, variation in telomere length at the end of the larval stage was unrelated to either cell proliferation rate or the relative level of oxidative DNA damage, and did not vary between the temperature treatments. This study suggests that salmon are able to restore the length of their telomeres during early development, which may possibly help to buffer potentially harmful environmental effects experienced in early life. Article in Journal/Newspaper Atlantic salmon Dryad Digital Repository (Duke University) |
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Dryad Digital Repository (Duke University) |
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topic |
cell proliferation environmental effect fish oxidative stress physiology |
spellingShingle |
cell proliferation environmental effect fish oxidative stress physiology McLennan, Darryl Armstrong, John D. Stewart, David C. Mckelvey, Simon Boner, Winnie Monaghan, Pat Metcalfe, Neil B. Data from: Telomere elongation during early development is independent of environmental temperatures in Atlantic salmon |
topic_facet |
cell proliferation environmental effect fish oxidative stress physiology |
description |
There is increasing evidence from endothermic vertebrates that telomeres, which cap the ends of chromosomes and play an important role in chromosome protection, decline in length during postnatal life and are a useful indicator of physiological state and expected lifespan. However, much less is currently known about telomere dynamics in ectothermic vertebrates, which are likely to differ from that of endotherms, at least in part due to the sensitivity of ectotherm physiology to environmental temperature. We report here on an experiment in which Atlantic salmon were reared through the embryonic and larval stages of development, and under differing temperatures, in order to examine the effects of environmental temperature during early life on telomere dynamics, oxidative DNA damage and cellular proliferation. Telomere length significantly increased between the embryonic and larval stages of development. Contrary to our expectations, variation in telomere length at the end of the larval stage was unrelated to either cell proliferation rate or the relative level of oxidative DNA damage, and did not vary between the temperature treatments. This study suggests that salmon are able to restore the length of their telomeres during early development, which may possibly help to buffer potentially harmful environmental effects experienced in early life. |
format |
Article in Journal/Newspaper |
author |
McLennan, Darryl Armstrong, John D. Stewart, David C. Mckelvey, Simon Boner, Winnie Monaghan, Pat Metcalfe, Neil B. |
author_facet |
McLennan, Darryl Armstrong, John D. Stewart, David C. Mckelvey, Simon Boner, Winnie Monaghan, Pat Metcalfe, Neil B. |
author_sort |
McLennan, Darryl |
title |
Data from: Telomere elongation during early development is independent of environmental temperatures in Atlantic salmon |
title_short |
Data from: Telomere elongation during early development is independent of environmental temperatures in Atlantic salmon |
title_full |
Data from: Telomere elongation during early development is independent of environmental temperatures in Atlantic salmon |
title_fullStr |
Data from: Telomere elongation during early development is independent of environmental temperatures in Atlantic salmon |
title_full_unstemmed |
Data from: Telomere elongation during early development is independent of environmental temperatures in Atlantic salmon |
title_sort |
data from: telomere elongation during early development is independent of environmental temperatures in atlantic salmon |
publishDate |
2018 |
url |
http://hdl.handle.net/10255/dryad.175559 https://doi.org/10.5061/dryad.ct7h4ds |
genre |
Atlantic salmon |
genre_facet |
Atlantic salmon |
op_relation |
doi:10.5061/dryad.ct7h4ds/1 doi:10.1242/jeb.178616 doi:10.5061/dryad.ct7h4ds McLennan D, Armstrong JD, Stewart DC, Mckelvey S, Boner W, Monaghan P, Metcalfe NB (2018) Telomere elongation during early development is independent of environmental temperatures in Atlantic salmon. Journal of Experimental Biology 221(11): jeb178616. http://hdl.handle.net/10255/dryad.175559 |
op_doi |
https://doi.org/10.5061/dryad.ct7h4ds https://doi.org/10.5061/dryad.ct7h4ds/1 https://doi.org/10.1242/jeb.178616 |
_version_ |
1766361887163809792 |