Data from: Fine-scale spatial covariation between infection prevalence and susceptibility in a natural population
The prevalence of infection varies dramatically on a fine spatial scale. Many evolutionary hypotheses are founded on the assumption that this variation is due to host genetics, such that sites with a high frequency of alleles conferring susceptibility are associated with higher infection prevalence....
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ftdryad:oai:v1.datadryad.org:10255/dryad.109463 2023-05-15T17:09:26+02:00 Data from: Fine-scale spatial covariation between infection prevalence and susceptibility in a natural population Gibson, Amanda Kyle Jokela, Jukka Lively, Curtis M. Lake Alexandrina in the Mackenzie basin of New Zealand 2016-02-22T15:12:52Z http://hdl.handle.net/10255/dryad.109463 https://doi.org/10.5061/dryad.t89hc unknown doi:10.5061/dryad.t89hc/1 doi:10.5061/dryad.t89hc/2 doi:10.5061/dryad.t89hc/3 doi:10.5061/dryad.t89hc/4 doi:10.5061/dryad.t89hc/5 doi:10.1086/686767 PMID:27322117 doi:10.5061/dryad.t89hc Gibson AK, Jokela J, Lively CM (2016) Fine-scale spatial covariation between infection prevalence and susceptibility in a natural population. The American Naturalist 188(1): 1-14. http://hdl.handle.net/10255/dryad.109463 Coevolution Ecology: evolutionary Ecology: spatial Evolution: host/parasite Article 2016 ftdryad https://doi.org/10.5061/dryad.t89hc https://doi.org/10.5061/dryad.t89hc/1 https://doi.org/10.5061/dryad.t89hc/2 https://doi.org/10.5061/dryad.t89hc/3 https://doi.org/10.5061/dryad.t89hc/4 https://doi.org/10.5061/dryad.t89hc/5 https://doi.org/1 2020-01-01T15:31:22Z The prevalence of infection varies dramatically on a fine spatial scale. Many evolutionary hypotheses are founded on the assumption that this variation is due to host genetics, such that sites with a high frequency of alleles conferring susceptibility are associated with higher infection prevalence. This assumption is largely untested and may be compromised at finer spatial scales where gene flow between sites is high. We put this assumption to the test in a natural snail-trematode interaction in which host susceptibility is known to have a strong genetic basis. A decade of field sampling revealed substantial spatial variation in infection prevalence between 13 sites around a small lake. Laboratory assays replicated over 3 years demonstrate striking variation in host susceptibility among sites in spite of high levels of gene flow between sites. We find that mean susceptibility can explain more than one-third of the observed variation in mean infection prevalence among sites. We estimate that variation in susceptibility and exposure together can explain the majority of variation in prevalence. Overall, our findings in this natural host-parasite system argue that spatial variation in infection prevalence covaries strongly with variation in the distribution of genetically based susceptibility, even at a fine spatial scale. Article in Journal/Newspaper Mackenzie Basin Dryad Digital Repository (Duke University) New Zealand |
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Open Polar |
collection |
Dryad Digital Repository (Duke University) |
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ftdryad |
language |
unknown |
topic |
Coevolution Ecology: evolutionary Ecology: spatial Evolution: host/parasite |
spellingShingle |
Coevolution Ecology: evolutionary Ecology: spatial Evolution: host/parasite Gibson, Amanda Kyle Jokela, Jukka Lively, Curtis M. Data from: Fine-scale spatial covariation between infection prevalence and susceptibility in a natural population |
topic_facet |
Coevolution Ecology: evolutionary Ecology: spatial Evolution: host/parasite |
description |
The prevalence of infection varies dramatically on a fine spatial scale. Many evolutionary hypotheses are founded on the assumption that this variation is due to host genetics, such that sites with a high frequency of alleles conferring susceptibility are associated with higher infection prevalence. This assumption is largely untested and may be compromised at finer spatial scales where gene flow between sites is high. We put this assumption to the test in a natural snail-trematode interaction in which host susceptibility is known to have a strong genetic basis. A decade of field sampling revealed substantial spatial variation in infection prevalence between 13 sites around a small lake. Laboratory assays replicated over 3 years demonstrate striking variation in host susceptibility among sites in spite of high levels of gene flow between sites. We find that mean susceptibility can explain more than one-third of the observed variation in mean infection prevalence among sites. We estimate that variation in susceptibility and exposure together can explain the majority of variation in prevalence. Overall, our findings in this natural host-parasite system argue that spatial variation in infection prevalence covaries strongly with variation in the distribution of genetically based susceptibility, even at a fine spatial scale. |
format |
Article in Journal/Newspaper |
author |
Gibson, Amanda Kyle Jokela, Jukka Lively, Curtis M. |
author_facet |
Gibson, Amanda Kyle Jokela, Jukka Lively, Curtis M. |
author_sort |
Gibson, Amanda Kyle |
title |
Data from: Fine-scale spatial covariation between infection prevalence and susceptibility in a natural population |
title_short |
Data from: Fine-scale spatial covariation between infection prevalence and susceptibility in a natural population |
title_full |
Data from: Fine-scale spatial covariation between infection prevalence and susceptibility in a natural population |
title_fullStr |
Data from: Fine-scale spatial covariation between infection prevalence and susceptibility in a natural population |
title_full_unstemmed |
Data from: Fine-scale spatial covariation between infection prevalence and susceptibility in a natural population |
title_sort |
data from: fine-scale spatial covariation between infection prevalence and susceptibility in a natural population |
publishDate |
2016 |
url |
http://hdl.handle.net/10255/dryad.109463 https://doi.org/10.5061/dryad.t89hc |
op_coverage |
Lake Alexandrina in the Mackenzie basin of New Zealand |
geographic |
New Zealand |
geographic_facet |
New Zealand |
genre |
Mackenzie Basin |
genre_facet |
Mackenzie Basin |
op_relation |
doi:10.5061/dryad.t89hc/1 doi:10.5061/dryad.t89hc/2 doi:10.5061/dryad.t89hc/3 doi:10.5061/dryad.t89hc/4 doi:10.5061/dryad.t89hc/5 doi:10.1086/686767 PMID:27322117 doi:10.5061/dryad.t89hc Gibson AK, Jokela J, Lively CM (2016) Fine-scale spatial covariation between infection prevalence and susceptibility in a natural population. The American Naturalist 188(1): 1-14. http://hdl.handle.net/10255/dryad.109463 |
op_doi |
https://doi.org/10.5061/dryad.t89hc https://doi.org/10.5061/dryad.t89hc/1 https://doi.org/10.5061/dryad.t89hc/2 https://doi.org/10.5061/dryad.t89hc/3 https://doi.org/10.5061/dryad.t89hc/4 https://doi.org/10.5061/dryad.t89hc/5 https://doi.org/1 |
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1766065527391780864 |